Patents by Inventor Renshan Ge

Renshan Ge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR REPAIRING SERTOLI CELL INJURY IN TESTES
    Publication number: 20240139284
    Abstract: The present disclosure relates to use of a Dvl3-DEP peptide in the preparation of a medicament for repairing Sertoli cell injury in testes, and belongs to the technical field of medicine preparation. The Dvl3-DEP peptide is used in the preparation of a medicament for repairing Sertoli cell injury in testes, and the Dvl3-DEP peptide has an amino acid sequence shown in SEQ ID NO. 1. Tests prove that the overexpression of a Dvl3-DEP-coding gene significantly increases the level of cell resistance, repairs the tight junction function among Sertoli cells destructed by perfluorooctane sulphonate (PFOS) infection and enables a tight junction among Sertoli cells, and repairs the tight junction structure among Sertoli cells.
    Type: Application
    Filed: May 19, 2023
    Publication date: May 2, 2024
    Inventors: Linxi Li, Lixiu Lv, Chuenyan Cheng, Jinjin Chu, Renshan Ge
  • USE OF Dvl3-DEP PEPTIDE IN PREPARATION OF MEDICAMENT FOR REPAIRING SERTOLI CELL INJURY IN TESTES
    Publication number: 20220193189
    Abstract: The present disclosure relates to use of a Dvl3-DEP peptide in the preparation of a medicament for repairing Sertoli cell injury in testes, and belongs to the technical field of medicine preparation. The Dvl3-DEP peptide is used in the preparation of a medicament for repairing Sertoli cell injury in testes, and the Dvl3-DEP peptide has an amino acid sequence shown in SEQ ID NO. 1.
    Type: Application
    Filed: December 2, 2021
    Publication date: June 23, 2022
    Inventors: Linxi LI, Lixiu LV, Chuenyan CHENG, Jinjin CHU, Renshan GE
  • Selective testicular 11beta-HSD inhibitors for the treatment of hypergonadism associated disorders and modulation of fertility
    Publication number: 20070219172
    Abstract: Methods for modulating testosterone levels using selective 11?-HSD1-dehydrogenase, 11?-HSD1-reductase and 11?-HSD2 dehydrogenase modulating compounds are described.
    Type: Application
    Filed: November 10, 2006
    Publication date: September 20, 2007
    Applicants: The Miriam Hospital, The Population Council
    Inventors: David Morris, Syed Latif, Matthew Hardy, Renshan Ge