Patents by Inventor Rente Lattmann

Rente Lattmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of hydroxy acids
    Patent number: 5098841
    Abstract: The invention relates to a preferably continuous process for the preparation of R- or S-2-hydroxy-4-phenylbutyric acid in very high enantiomeric purity, which comprises reducing 2-oxo-4-phenylbutyric acid with the enzyme D-lactate dehydrogenase from Staphylococcus epidermidis or with the enzyme L-lactate dehydrogenase from bovine heart, respectively, in the presence of NAD(H) and formate or ethanol and formate dehydrogenase or alcohol dehydrogenase, respectively. R-2-hydroxy-4-phenylbutyric acid is a valuable intermediate in the preparation of ACE inhibitors or their precursors.
    Type: Grant
    Filed: June 2, 1989
    Date of Patent: March 24, 1992
    Assignee: CIBA-GEIGY Corporation
    Inventors: Oreste Ghisalba, Daniel Gygax, Rente Lattmann, Hans-Peter Schar, Elke Schmidt, Gottfried Sedelmeier