Patents by Inventor Renukadevi Patil

Renukadevi Patil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES
    Publication number: 20180189460
    Abstract: Disclosed is a five-feature pharmacophore model of LPA2 receptor specific agonists. Compounds may be identified as agonists of the LPA2 receptor using the five-feature pharmacophore model.
    Type: Application
    Filed: November 19, 2017
    Publication date: July 5, 2018
    Inventors: Renukadevi Patil, James Fells, Duane Miller, Gabor Tigyi
  • Compounds with increased specificity for the treatment of glioma
    Patent number: 9187449
    Abstract: Disclosed are compounds for the treatment of cancer. Compounds disclosed herein are particularly effective for the selective inhibition of glioma cells.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: November 17, 2015
    Assignee: The University of Tennessee Research Foundation
    Inventors: Duane D. Miller, Shivaputra Appanna Patil, Renukadevi Patil, Terreia Jones, Amira Ahmed, Likeselam Asres, Charles Ryan Yates, Eldon Geisert
  • LPAreceptor-specific benzoic acid derivatives
    Patent number: 9056835
    Abstract: Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA2 receptor. Compounds of the invention comprise non-lipid benzoic acid derivatives.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: June 16, 2015
    Assignee: The University of Tennessee Research Foundation
    Inventors: Renukadevi Patil, James Fells, Duane D. Miller, Gabor Tigyi
  • COMPOUNDS WITH INCREASED SPECIFICITY FOR THE TREATMENT OF GLIOMA
    Publication number: 20140296286
    Abstract: Disclosed are compounds for the treatment of cancer. Compounds disclosed herein are particularly effective for the selective inhibition of glioma cells.
    Type: Application
    Filed: March 25, 2014
    Publication date: October 2, 2014
    Applicant: University of Tennessee Research Foundation
    Inventors: Duane D. Miller, Shivaputra Appanna Patil, Renukadevi Patil, Terreia Jones, Amira Ahmed, Likeselam Asres, Charles Ryan Yates, Eldon Geisert
  • LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES
    Publication number: 20140206714
    Abstract: Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA2 receptor. Compounds of the invention comprise non-lipid benzoic acid derivatives. Further disclosed is a pharmacophore of LPA2 receptor.
    Type: Application
    Filed: March 21, 2014
    Publication date: July 24, 2014
    Applicant: University of Tennessee Research Foundation
    Inventors: Renukadevi Patil, James Fells, Duane Miller, Gabor Tigyi
  • Inhibitors of autotaxin
    Patent number: 8673882
    Abstract: Stabilized benzyl phosphonic acid and naphthyl phosphonic acid analog compounds are effective in inhibiting the activity of autotaxin.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: March 18, 2014
    Assignee: University of Tennessee Research Foundation
    Inventors: Renuka Gupte, Renukadevi Patil, Gabor Tigyi, Duane D. Miller
  • LPA2 Receptor-Specific Benzoic Acid Derivatives
    Publication number: 20140057936
    Abstract: Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA2 receptor. Compounds of the invention comprise non-lipid benzoic acid derivatives.
    Type: Application
    Filed: August 27, 2013
    Publication date: February 27, 2014
    Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Renukadevi Patil, James Fells, Duane D. Miller, Gabor Tigyi
  • Therapeutic tetrahydroisoquinoline-based compositions for cancer therapy
    Patent number: 8507523
    Abstract: Disclosed are therapeutic tetrahydroisoquinoline compositions for the treatment of cancer, these compositions having selectivity for cancer cells while demonstrating few, if any, deleterious side effects on normal cells.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: August 13, 2013
    Inventors: Renukadevi Patil, Charles Ryan Yates, Duane D. Miller, Eldon E. Geisert
  • Inhibitors of Autotaxin
    Publication number: 20120190650
    Abstract: Stabilized benzyl phosphonic acid and naphthyl phosphonic acid analog compounds are effective in inhibiting the activity of autotaxin.
    Type: Application
    Filed: January 19, 2012
    Publication date: July 26, 2012
    Applicant: University of Tennessee Research Foundation
    Inventors: Renuka Gupte, Renukadevi Patil, Gabor Tigyi, Duane D. Miller
  • 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES EFFECTIVE AS ANTIGLIOMA AGENTS, METHODS OF MAKING, AND THEIR USE
    Publication number: 20120059032
    Abstract: Disclosed are tetrahydroisoquinoline-derivative compounds effective for killing cancer cells, shrinking tumor size, and treating cancer.
    Type: Application
    Filed: March 7, 2011
    Publication date: March 8, 2012
    Applicant: University of Tennessee Research Foundation
    Inventors: Renukadevi Patil, Shivaputra A. Patil, Duane D. Miller, Charles Ryan Yates, Eldon E. Geisert
  • Therapeutic Tetrahydroisoquinoline-Based Compositions for Cancer Therapy
    Publication number: 20080146597
    Abstract: Disclosed are therapeutic tetrahydroisoquinoline compositions for the treatment of cancer, these compositions having selectivity for cancer cells while demonstrating few, if any, deleterious side effects on normal cells.
    Type: Application
    Filed: November 21, 2007
    Publication date: June 19, 2008
    Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Renukadevi Patil, Charles Ryan Yates, Duane D. Miller, Eldon E. Geisert
  • Substituted Tetrahydroisoquinoline Compounds for Cancer Therapy
    Publication number: 20080033007
    Abstract: Disclosed are compounds that are effective for selectively killing cancer cells. Compounds have been demonstrated to be especially effective for killing glioma cells, while exhibiting low toxicity to normal cells.
    Type: Application
    Filed: April 18, 2007
    Publication date: February 7, 2008
    Inventors: Duane Miller, Eldon Geisert, Charles Yates, Renukadevi Patil, William Orr, XiangDi Wang, Fei Ma, Oleg Kirichenko