Patents by Inventor Renukaradhya Gourapura

Renukaradhya Gourapura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MANNOSE CONJUGATED CHITOSAN-BASED INFLUENZA NANOVACCINE FORMULATIONS AND USES THEREOF
    Publication number: 20230293666
    Abstract: Disclosed herein are nanoparticles comprising mannose conjugated chitosan and an inactivated influenza A virus (IAV) antigen, wherein the mannose conjugated chitosan encapsulates the inactivated IAV antigen. In some embodiments, the nanoparticle further comprises tripolyphosphate. Also disclosed are methods of reducing transmission of an influenza A virus, and methods of eliciting an immune response against an influenza A virus, in a subject compared to a control comprising administering to the subject a nanoparticle comprising mannose conjugated chitosan and an inactivated influenza A virus (IAV) antigen, wherein the mannose conjugated chitosan encapsulates the inactivated IAV antigen.
    Type: Application
    Filed: February 9, 2023
    Publication date: September 21, 2023
    Inventors: Renukaradhya Gourapura, Sankar Renu
  • Nanoparticle compositions for vaccines
    Patent number: 11123415
    Abstract: The present disclosure relates to nanoparticle compositions for use as vaccines against Salmonella.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: September 21, 2021
    Assignee: Ohio State Innovation Foundation
    Inventors: Renukaradhya Gourapura, Ramesh Selvaraj, Sankar Renu
  • NANOPARTICLE COMPOSITIONS FOR SALMONELLA VACCINES
    Publication number: 20210093705
    Abstract: The present disclosure relates to nanoparticle compositions for use as vaccines against Salmonella. Disclosed herein is a composition comprising: a Salmonella enteritidis outer membrane protein (OMP) or Salmonella enteritidis killed whole antigenic extracted (KAg) protein; and a polyanhydride or chitosan nanoparticle. In some embodiments, the nanoparticle further comprises flagellar protein. Disclosed herein is a vaccine comprising: a composition comprising a Salmonella enteritidis OMP protein or Salmonella enteritidis killed whole antigenic extracted (KAg) protein; a polyanhydride or chitosan nanoparticle; and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 16, 2018
    Publication date: April 1, 2021
    Inventors: Renukaradhya GOURAPURA, Ramesh SELVARAJ, Sankar RENU
  • MUCOADHESIVE NANOPARTICLE ENTRAPPED INFLUENZA VIRUS VACCINE DELIVERY SYSTEM
    Publication number: 20200306364
    Abstract: Disclosed herein are nanoparticles comprising chitosan and an inactivated influenza A virus (IAV) antigen, wherein the chitosan encapsulates the inactivated IAV antigen. In some embodiments, the nanoparticle further comprises tripolyphosphate. In some embodiments, the nanoparticle reduces nasal shedding of an influenza A virus. In some embodiments, the nanoparticle elicits an increased amount of IgA antibody in a subject. Also disclosed are methods of reducing transmission of an influenza A virus, and methods of eliciting an immune response against an influenza A virus, in a subject compared to a control comprising administering to the subject a nanoparticle comprising chitosan and an inactivated influenza A virus (IAV) antigen, wherein the chitosan encapsulates the inactivated IAV antigen.
    Type: Application
    Filed: November 30, 2018
    Publication date: October 1, 2020
    Inventors: Renukaradhya GOURAPURA, Santosh DHAKAL, Sankar RENU
  • Nanoparticle based vaccine strategy against swine influenza virus
    Patent number: 10682314
    Abstract: Disclosed herein are methods and compositions for treating or preventing swine influenza in a subject.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: June 16, 2020
    Assignee: Ohio State Innovation Foundation
    Inventors: Renukaradhya Gourapura, Santosh Dhakal, Jagadish Hiremath, Chang-Won Lee
  • NANOPARTICLE BASED VACCINE STRATEGY AGAINST SWINE INFLUENZA VIRUS
    Publication number: 20180243228
    Abstract: Disclosed herein are methods and compositions for treating or preventing swine influenza in a subject.
    Type: Application
    Filed: May 26, 2016
    Publication date: August 30, 2018
    Inventors: Renukaradhya GOURAPURA, Santosh DHAKAL, Jagadish HIREMATH, Chang-Won LEE
  • Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome
    Patent number: 9005665
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: April 14, 2015
    Assignee: Ohio State Innovation Foundation
    Inventors: Renukaradhya Gourapura, Varun Dwivedi, Basavaraj Binjawadagi, Jordi Torrelles
  • COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME
    Publication number: 20140004193
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Application
    Filed: April 24, 2013
    Publication date: January 2, 2014
    Inventors: Renukaradhya Gourapura, Varun Dwivedi, Cordelia Manickam, Ruthi Patterson