Patents by Inventor Renukaradhya J. Gourapura

Renukaradhya J. Gourapura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11524061
    Abstract: The present disclosure relates to nanoparticle compositions for use as vaccines against Clostridium perfringens in poultry which causes necrotic enteritis in poultry. Such compositions include one or more Clostridium perfringens extracellular proteins entrapped in a polyanhydride or chitosan nanoparticle. The one or more Clostridium perfringens extracellular proteins may include one or more Clostridium perfringens toxins, such as, for example, alpha toxin (CPA), beta toxin (CPB), epsilon toxin (ETX), iota toxin (ITX), perfringolysin O (PFO), enterotoxin (CPE), beta2 toxin (CPB2), or NetB toxin. In some aspects, the composition further includes a Salmonella enteritidis flagellar protein. The present invention also includes methods for the oral delivery of one or more Clostridium perfringens extracellular proteins to the mucosal membrane of the intestinal tract of a bird of the order Galliformes.
    Type: Grant
    Filed: February 4, 2021
    Date of Patent: December 13, 2022
    Assignees: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC, THE OHIO STATE UNIVERSITY
    Inventors: Ramesh Kumar Selvaraj, Gabriel Akerele, Sankar Renu, Renukaradhya J. Gourapura
  • Publication number: 20210236617
    Abstract: The present disclosure relates to nanoparticle compositions for use as vaccines against Clostridium perfringens in poultry which causes necrotic enteritis in poultry. Such compositions include one or more Clostridium perfringens extracellular proteins entrapped in a polyanhydride or chitosan nanoparticle. The one or more Clostridium perfringens extracellular proteins may include one or more Clostridium perfringens toxins, such as, for example, alpha toxin (CPA), beta toxin (CPB), epsilon toxin (ETX), iota toxin (ITX), perfringolysin O (PFO), enterotoxin (CPE), beta2 toxin (CPB2), or NetB toxin. In some aspects, the composition further includes a Salmonella enteritidis flagellar protein. The present invention also includes methods for the oral delivery of one or more Clostridium perfringens extracellular proteins to the mucosal membrane of the intestinal tract of a bird of the order Galliformes.
    Type: Application
    Filed: February 4, 2021
    Publication date: August 5, 2021
    Inventors: Ramesh Kumar Selvaraj, Gabriel Akerele, Sankar Renu, Renukaradhya J. Gourapura
  • Patent number: 10478488
    Abstract: The present invention relates to the field of pharmaceutical and vaccine formulations. More specifically, formulations which comprise an antigen comprising a mixture of oligopeptides loaded into liposome nanoparticles, optionally including an adjuvant, to provide an improved immune response.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: November 19, 2019
    Assignee: Southwest Research Institute
    Inventors: Xingguo Cheng, Kenneth H. Carson, Joseph A. McDonough, Renukaradhya J. Gourapura, Chang Won Lee, Santosh Dhakal
  • Patent number: 10279028
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: May 7, 2019
    Assignee: Ohio State Innovation Foundation
    Inventors: Renukaradhya J. Gourapura, Varun Dwivedi, Basavaraj S. Binjawadagi, Jordi Torrelles
  • Publication number: 20190099482
    Abstract: The present invention relates to the field of pharmaceutical and vaccine formulations. More specifically, formulations which comprise an antigen comprising a mixture of oligopeptides loaded into liposome nanoparticles, optionally including an adjuvant, to provide an improved immune response.
    Type: Application
    Filed: October 3, 2017
    Publication date: April 4, 2019
    Inventors: Xingguo CHENG, Kenneth H. CARSON, Joseph A. McDONOUGH, Renukaradhya J. GOURAPURA, Chang Won LEE, Santosh DHAKAL
  • Publication number: 20180185469
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Application
    Filed: December 14, 2017
    Publication date: July 5, 2018
    Inventors: Renukaradhya J. Gourapura, Varun Dwivedi, Basavaraj S. Binjawadagi, Jordi Torrelles
  • Patent number: 9872898
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: January 23, 2018
    Assignee: Ohio State Innovation Founation
    Inventors: Renukaradhya J. Gourapura, Varun Dwivedi, Basavaraj S. Binjawadagi, Jordi Torrelles
  • Publication number: 20170080078
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Application
    Filed: October 3, 2016
    Publication date: March 23, 2017
    Inventors: Renukaradhya J. Gourapura, Varun Dwivedi, Basavaraj S. Binjawadagi, Jordi Torrelles
  • Patent number: 9457074
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: October 4, 2016
    Assignee: Ohio State Innovation Foundation
    Inventors: Renukaradhya J. Gourapura, Varun Dwivedi, Basavaraj S. Binjawadagi, Jordi Torrelles
  • Publication number: 20150265696
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Application
    Filed: February 23, 2015
    Publication date: September 24, 2015
    Inventors: Renukaradhya J. Gourapura, Varun Dwivedi, Basavaraj S. Binjawadagi, Jordi Torrelles