Patents by Inventor Reuben Shaw

Reuben Shaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KRAS INHIBITOR AND HDAC INHIBITOR COMBINATION FOR THE TREATMENT OF CANCER
    Publication number: 20240398814
    Abstract: Provided herein are pharmaceutical compositions comprising KRAS inhibitors and HDAC inhibitors and methods of administering KRAS inhibitors and HDAC inhibitors for the treatment/prevention of cancer. In particular, an HDAC inhibitor is administered to overcome KRAS inhibitor resistance in KRAS, LKB1 mutant lung cancer.
    Type: Application
    Filed: June 5, 2024
    Publication date: December 5, 2024
    Inventors: Lillian Jennifer EICHNER, Reuben SHAW
  • COMPOUNDS FOR PROTECTION OF NOISE-INDUCED HEARING-LOSS
    Publication number: 20240180882
    Abstract: The present disclosure provides compositions and methods for prevention or treatment of hearing loss. In some examples, a composition for preventing or treating hearing loss comprises at least one compound that activates AMPK in at least one hair cell.
    Type: Application
    Filed: March 4, 2022
    Publication date: June 6, 2024
    Applicants: The Regents of the University of California, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CALIFORNIA INSTITUTE OF TECHNOLOGY, THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
    Inventors: Rick A FRIEDMAN, Ely BOUSSATY, Andre HOELZ, Steven OLSON, Reuben SHAW
  • ULK1 COMPOSITIONS, INHIBITORS, SCREENING AND METHODS OF USE
    Publication number: 20130040310
    Abstract: This disclosure relates to methods and compositions useful for the treatment of cancer and diseases and disorders associated with autophagy.
    Type: Application
    Filed: December 15, 2010
    Publication date: February 14, 2013
    Applicant: Salk Institute for Biological Studies
    Inventors: Reuben Shaw, Daniel F. Egan, Maria Mihavlova, David Shackelford
  • INCREASING LIFESPAN BY MODULATING CRTC EXPRESSION OR LOCALIZATION, AND METHODS OF SCREENING FOR MODULATORS OF SAME
    Publication number: 20120172413
    Abstract: The invention relates to the field of longevity enhancement. More particularly, the invention provides compositions and methods relating to CRTC modulation. In certain embodiments, the invention provides compositions and methods for enhancing longevity in an organism by inhibiting CRTC activity, such as, for example, inhibiting CRTC expression or cellular localization in the organism.
    Type: Application
    Filed: June 28, 2010
    Publication date: July 5, 2012
    Applicant: THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
    Inventors: Andrew Dillin, William Mair, Ianessa Morantte, Reuben Shaw