Patents by Inventor Reut YOSEF

Reut YOSEF has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
    Patent number: 12083111
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: September 10, 2024
    Assignee: Vidac Pharma Ltd ..
    Inventors: Vered Behar, Oren Menahem Becker, Reut Yosef Hamo, Eyal Dor-On
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR TREATING HEXOKINASE-2 (HK2)-EXPRESSING CANCERS
    Publication number: 20220143004
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for treating, inhibiting, or suppressing a hexokinase-2 (HK2)-expressing cancer.
    Type: Application
    Filed: January 25, 2022
    Publication date: May 12, 2022
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Hadas Tamar PAHIMA, Reut YOSEF HAMO
  • Use of hexokinase 2/mitochondria-detaching compounds for treating hexokinase-2 (HK2)-expressing cancers
    Patent number: 11266639
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for treating, inhibiting, or suppressing a hexokinase-2 (HK2)-expressing cancer.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: March 8, 2022
    Assignee: VIDAC PHARMA LTD.
    Inventors: Vered Behar, Oren Menahem Becker, Hadas Tamar Pahima, Reut Yosef Hamo
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR ACTIVATING IMMUNE RESPONSES
    Publication number: 20210369697
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Application
    Filed: August 17, 2021
    Publication date: December 2, 2021
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Reut YOSEF HAMO, Eyal DOR-ON
  • Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
    Patent number: 11096935
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: August 24, 2021
    Assignee: VIDAC PHARMA LTD
    Inventors: Vered Behar, Oren Menahem Becker, Reut Yosef Hamo, Eyal Dor-On
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR ACTIVATING IMMUNE RESPONSES
    Publication number: 20200188381
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Application
    Filed: January 29, 2020
    Publication date: June 18, 2020
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Reut YOSEF HAMO, Eyal DOR-ON
  • Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
    Patent number: 10682346
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: June 16, 2020
    Assignee: VIDAC PHARMA LTD.
    Inventors: Vered Behar, Oren Menahem Becker, Reut Yosef Hamo, Eyal Dor-On
  • METHOD OF PROMOTING HAIR GROWTH
    Publication number: 20180345047
    Abstract: A method of promoting hair growth or reducing hair loss in a subject is disclosed. The method comprises contacting the scalp and skin region in which there is desire for hair growth of the subject with an effective amount of at least one agent which down-regulates an activity and/or an amount of a protein selected from the group consisting of p21, Bcl-xL and Bcl-w. Compositions capable of same are also disclosed.
    Type: Application
    Filed: February 25, 2016
    Publication date: December 6, 2018
    Inventors: Valery KRIZHANOVSKY, Reut YOSEF, Noam PILPEL, Ittai BEN-PORATH, Liat DASSA, Ronit AMIEL-TOKARSKY
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR TREATING HEXOKINASE-2 (HK2)-EXPRESSING CANCERS
    Publication number: 20180303820
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for treating, inhibiting, or suppressing a hexokinase-2 (HK2)-expressing cancer.
    Type: Application
    Filed: November 7, 2017
    Publication date: October 25, 2018
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Hadas Tamar PAHIMA, Reut YOSEF HAMO
  • USE OF HEXOKINASE 2/MITOCHONDRIA-DETACHING COMPOUNDS FOR ACTIVATING IMMUNE RESPONSES
    Publication number: 20180303819
    Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.
    Type: Application
    Filed: November 7, 2017
    Publication date: October 25, 2018
    Applicant: Vidac Pharma Ltd.
    Inventors: Vered BEHAR, Oren Menahem BECKER, Reut YOSEF HAMO, Eyal DOR-ON
  • AGENTS FOR DOWNREGULATION OF THE ACTIVITY AND/OR AMOUNT OF BCL-XL AND/OR BCL-W
    Publication number: 20160122758
    Abstract: A method of treating an inflammatory or fibrotic disease in a subject is disclosed. The method comprises administering to the subject a therapeutically effective amount of an agent which down-regulates an activity and/or an amount of Bcl-xL and/or Bcl-w and/or p21, with the proviso that the inflammatory disease is not cancer.
    Type: Application
    Filed: April 13, 2014
    Publication date: May 5, 2016
    Inventors: Valery KRIZHANOVSKY, Noam PILPEL, Reut YOSEF