Patents by Inventor Revati Tatake

Revati Tatake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid constructs useful for glucose regulated production of human insulin in somatic cell lines
    Publication number: 20070009498
    Abstract: Unique multifunctional nucleotide expression cassettes comprising a nucleotide sequence encoding a human protease driven by a glucose-regulatable promoter, a nucleotide sequence encoding human proinsulin having sites at its B-C and C-A junctions altered to permit cleavage by the human protease, and a CMV promoter driving the transcription of the nucleotide sequence encoding the human proinsulin, such cassettes optionally having polyadenylation sequences after each structural gene and the nucleotide sequence encoding human proinsulin optionally carrying an H10D variant, and cells transformed thereby.
    Type: Application
    Filed: January 17, 2006
    Publication date: January 11, 2007
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Revati Tatake, Richard Schneiderman, Randall Barton
  • Methods for improving cell line activity in immunoisolation devices
    Publication number: 20060029584
    Abstract: Methods for maintaining and improving the secretory activity of cells housed in immunoisolation devices.
    Type: Application
    Filed: September 27, 2005
    Publication date: February 9, 2006
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Richard Schneiderman, Revati Tatake, Randall Barton