Patents by Inventor Revital Lifshitz-Liron

Revital Lifshitz-Liron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of ramelteon and its intermediates
    Patent number: 8084630
    Abstract: The present invention provides processes and intermediates for the synthesis of ramelteon.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: December 27, 2011
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Dhirenkumar N. Mistry, Sanjay L. Vasoya, Michal Rafilovich, Elena Ben Moha-Lerman, Revital Lifshitz-Liron
  • Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation
    Patent number: 7687636
    Abstract: The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: March 30, 2010
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Judith Aronhime, Revital Lifshitz-Liron
  • Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them
    Patent number: 7687642
    Abstract: Provided are crystalline forms of fluvastatin sodium and processes for their preparation.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: March 30, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Revital Lifshitz-Liron, Tamas Koltai, Judith Aronhime, Nurit Perlman, Sharon Avhar-Maydan
  • NILOTINIB INTERMEDIATES AND PREPARATION THEREOF
    Publication number: 20100016590
    Abstract: Intermediates of Nilotinib were prepared, including, for example, 3-(trifluoromethyl-5-(4-methyl-1H-imidazole-1-yl)-benzeneamine; 3-(4-(pyridin-3-yl)pyrimidin-2-ylamino) -4-methylbenzoyl halogen dihydrochloride; and N-(3-Bromo-5-trifluoromethylphenyl)-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide. Nilotinib.3HCl and its crystalline forms are also described.
    Type: Application
    Filed: July 17, 2009
    Publication date: January 21, 2010
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES LTD.
    Inventors: Yanling WANG, Jie LI, Vinod Kumar KANSAL, Jirang ZHU, Revital LIFSHITZ-LIRON, Dhirenkumar N. MISTRY, Sanjay L. VASOYA, Sundaraselvan ARIYAMUTHU, Gideon PILARSKI, Xungui HE
  • Crystalline forms of quetiapine hemifumarate
    Publication number: 20100016579
    Abstract: The present invention relates to novel crystalline forms of quetiapine hemifumarate, denominated quetiapine hemifumarate form II and quetiapine hemifumarate form III. These novel crystalline forms of quetiapine hemifumarate have been characterized by methods including x-ray powder diffraction (XRD), Fourier transform IR spectroscopy (FTIR), differential scanning calorimetry (DSC), and thermal gravimetric analysis (TGA). Methods for preparation of the novel crystalline quetiapine hemifumarate form II as its chloroform solvate and its dichloromethane solvate, form III as its chloroform solvate, and form I are provided.
    Type: Application
    Filed: June 8, 2009
    Publication date: January 21, 2010
    Inventors: Revital Lifshitz-Liron, Eti Kovalevski-Ishai, Ben-Zion Dolitzky, Shlomit Wizel, Rami Lidor-Hadas
  • PROCESSES FOR PURIFYING VARENICLINE L-TARTRATE SALT AND PREPARING CRYSTALLINE FORMS OF VARENICLINE L-TARTRATE SALT
    Publication number: 20100010221
    Abstract: Processes for purifying Varenicline base or the L-tartrate salt thereof and for preparing Varenicline L-tartrate crystalline forms A and B are provided.
    Type: Application
    Filed: May 28, 2009
    Publication date: January 14, 2010
    Inventors: Revital Lifshitz-Liron, Shalom Shabat, Sharon Tomer, Yuriy Raizi, Eyal Gilboa, Pramod Kumar Pandey
  • Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation
    Patent number: 7589211
    Abstract: The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: September 15, 2009
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Judith Aronhime, Revital Lifshitz-Liron
  • Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation
    Patent number: 7582768
    Abstract: The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: September 1, 2009
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Judith Aronhime, Revital Lifshitz-Liron
  • Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them
    Publication number: 20090209611
    Abstract: Provided are crystalline forms of fluvastatin sodium and processes for their preparation.
    Type: Application
    Filed: March 25, 2009
    Publication date: August 20, 2009
    Inventors: Revital Lifshitz-Liron, Tamas Koltai, Judith Aronhime, Nurit Perlman, Sharon Avhar-Maydan
  • Novel Process For Making Bisphosphonic Acids Using Diluents Other Than Halogenated Hydrocarbons
    Publication number: 20090209763
    Abstract: Provided is a novel method of making bisphosphonic acids, e.g. risedronic acid, including the step of combining a carboxylic acid, phosphorous acid, and a halophosphorous compound in the presence of a diluent that is an aromatic hydrocarbon or a silicone fluid. When the diluent is an aromatic hydrocarbon, an inert support or ortho-phosphoric acid codiluent is advantageously included.
    Type: Application
    Filed: February 10, 2009
    Publication date: August 20, 2009
    Inventors: Rami Lidor-Hadas, Zvi Harel, Revital Lifshitz-Liron, Eti Kovalevski-Ishai
  • Crystal forms of Cinacalcet HCI and processes for their preparation
    Patent number: 7563930
    Abstract: Provided are crystalline forms of Cinacalet HCl and processes for their preparation.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: July 21, 2009
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Shlomit Wizel, Revital Lifshitz-Liron, Sharon Avhar-Maydan
  • Solid and crystalline ibandronate sodium and processes for preparation thereof
    Patent number: 7563918
    Abstract: The present invention relates to solid amorphous and crystalline forms of ibandronate sodium.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: July 21, 2009
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Revital Lifshitz-Liron, Thomas Bayer, Judith Aronhime, Michael Pinchasov
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20090143459
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VII, VIII, IX, IXa, X, XI, XII, XIV, XVI and XVII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: September 30, 2008
    Publication date: June 4, 2009
    Inventors: Limor Tessler, Judith Aronhime, Revital Lifshitz-Liron, Dalia Maidan-Hanoch, Nir Hasson
  • Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them
    Publication number: 20090118518
    Abstract: Provided are crystalline forms of fluvastatin sodium and processes for their preparation.
    Type: Application
    Filed: April 30, 2008
    Publication date: May 7, 2009
    Inventors: Revital Lifshitz-Liron, Tamas Koltai, Judith Aronhime, Nurit Perlman, Sharon Avhar-Maydan
  • Polymorphic forms of ramelteon and processes for preparation thereof
    Publication number: 20090105490
    Abstract: An amorphous form of ramelteon is provided, as well as mixtures of amorphous and crystalline ramelteon. Also provided are methods of preparing amorphous ramelteon and mixtures of amorphous and crystalline ramelteon, pharmaceutical compositions comprising amorphous ramelteon and mixtures of amorphous and crystalline ramelteon, and methods of treatment of insomnia using the compositions of the invention.
    Type: Application
    Filed: July 14, 2008
    Publication date: April 23, 2009
    Inventors: Nurit Perlman, Michal Rafilovich, Rinat Moshkovits-Kaptsan, Elena Ben Moha-Lerman, Revital Lifshitz-Liron
  • Solid and crystalline ibandronic acid
    Patent number: 7511174
    Abstract: Provided are novel crystalline and amorphous forms of ibandronic acid, methods for their preparation, and pharmaceutical compositions containing them. Also provided are methods for purifying and assaying ibandronic acid in any crystalline form (or amorphous).
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: March 31, 2009
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Thomas Bayer, Ben-Zion Dolitzky, Revital Lifshitz-Liron, Inna Perutski, Michael Pinchasov
  • Solid and crystalline ibandronic acid
    Publication number: 20090069598
    Abstract: Provided are novel crystalline forms of ibandronic acid, physical data, methods for their preparation, and uses therefor. Also provided are methods for purifying and assaying ibandronic acid in any crystalline form.
    Type: Application
    Filed: October 15, 2008
    Publication date: March 12, 2009
    Inventors: Thomas Bayer, Ben-Zion Dolitzky, Revital Lifshitz-Liron, Inna Perutski, Michael Pinchasov
  • PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES
    Publication number: 20090069581
    Abstract: The present invention provides processes and intermediates for the synthesis of ramelteon.
    Type: Application
    Filed: June 2, 2008
    Publication date: March 12, 2009
    Inventors: Vinod Kumar KANSAL, Dhirenkumar N. MISTRY, Sanjay L. VASOYA, Michal RAFILOVICH, Elena Ben LERMAN-MOHA, Revital LIFSHITZ-LIRON
  • Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Patent number: 7501450
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VII, VIII, IX, IXa, X, XI, XII, XIV, XVI and XVII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: March 10, 2009
    Assignee: Teva Pharaceutical Industries Ltd.
    Inventors: Limor Tessler, Judith Aronhime, Revital Lifshitz-Liron, Dalia Maidan-Hanoch, Nir Hasson
  • Amorphous ibandronic acid
    Publication number: 20090023949
    Abstract: Amorphous ibandronic acid is provided with methods for its preparation. The methods include dissolution of ibandronic acid in a solvent such as acetonitrile, DMSO, methanol, or water, and spray drying.
    Type: Application
    Filed: July 10, 2008
    Publication date: January 22, 2009
    Inventors: Thomas Bayer, Ben-Zion Dolitzky, Revital Lifshitz-Liron, Inna Perutski, Michael Pinchasov