Patents by Inventor Rex A. Jennings

Rex A. Jennings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperidine Derivatives
    Publication number: 20100120858
    Abstract: The invention relates to compounds of Formula (I) and pharmaceutically acceptable acid addition salts thereof, wherein *, X1, X2, R5A, R5B, R6, R7, and R8 are as defined in the specification; pharmaceutical compositions; therapeutic combinations; and methods of treating diseases and disorders.
    Type: Application
    Filed: August 13, 2007
    Publication date: May 13, 2010
    Inventors: Bradley W. Caprathe, Rocco D. Gogliotti, Rex A. Jennings, Lloyd J. Simons
  • CYCLOALKYLAMINO ACID DERIVATIVES
    Publication number: 20090227641
    Abstract: The invention relates to compounds of formula I and to pharmaceutically acceptable salts, prodrugs, solvates or hydrates thereof. This invention also relates to a method of using such compounds in the treatment of hyperproliferative diseases and autoimmune diseases in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: November 7, 2008
    Publication date: September 10, 2009
    Inventors: Samit K. Bhattacharya, Matthew F. Brown, Peter H. Dorff, Susan D. LaGreca, John W. Mickelson, Joseph A. Cornicelli, David L. Brown, Rex Jennings, John K. Walker, Rita Huff, Joseph W. Strohbach, Robert J. Maguire
  • PIPERIDINE DERIVATIVES
    Publication number: 20070142389
    Abstract: The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein R6 and R10 have any of the values defined therefor in the specification; pharmaceutical compositions; methods of treating conditions, diseases, and disorders; and therapeutic combinations.
    Type: Application
    Filed: December 14, 2006
    Publication date: June 21, 2007
    Applicant: PFIZER INC.
    Inventors: Michelle Bruendl, Keri Greene, Rex Jennings, Scott Lazerwith, Joe Nahra, Patrick O'Brien, Kimberly Para, Susan Sheehan
  • Crystalline [R- (R*,R*)]-2-(4-Dfluorophenyl)-.beta.,.delta.-dihydroxy-5-(1-methylethyl)- 3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin)
    Patent number: 5969156
    Abstract: Crystalline forms of atorvastatin and hydrates thereof are useful hypolipidemic and hypocholesterolemic agents.
    Type: Grant
    Filed: September 29, 1997
    Date of Patent: October 19, 1999
    Assignee: Warner-Lambert Company
    Inventors: Christopher A. Briggs, Rex A. Jennings, Robert Wade, Kikuko Harasawa, Shigeru Ichikawa, Kazuo Minohara, Shinsuke Nakagawa
  • Process for cyclic amino acid anticonvulsant compounds
    Patent number: 5362883
    Abstract: An improved process for the preparation of cyclic amino acids by a novel synthesis is described where a dinitrile derivative is converted in two steps to the desired products, as well as valuable intermediates used in the process.
    Type: Grant
    Filed: March 8, 1994
    Date of Patent: November 8, 1994
    Assignee: Warner-Lambert Company
    Inventors: Rex A. Jennings, Don R. Johnson, Ronald E. Seamans, James R. Zeller
  • Process for cyclic amino acid anticonvulsant compounds
    Patent number: 5319135
    Abstract: An improved process for the preparation of cyclic amino acids by a novel synthesis is described where a dinitrile derivative is converted in two steps to the desired products, as well as valuable intermediates used in the process.
    Type: Grant
    Filed: June 4, 1993
    Date of Patent: June 7, 1994
    Assignee: Warner-Lambert Company
    Inventors: Rex A. Jennings, Don R. Johnson, Ronald E. Seamans, James R. Zeller
  • Process for the synthesis of 2,6-dichloro-5-fluoronicotinic acid and 2,6-dichloro-5-fluoronicotinoyl chloride
    Patent number: 5204478
    Abstract: An improved process for the preparation of 2,6-dichloro-5-fluoronicotinoyl chloride is described where a 2,6-dihydroxy-5-fluoronicotinic acid ester is converted in one step using phosphorus oxychloride and a lithium reagent to 2,6-dichloro-5-fluoronicotinoyl chloride and subsequent basic hydrolysis affords 2,6-dichloro-5-fluoronicotinic acid.
    Type: Grant
    Filed: August 20, 1992
    Date of Patent: April 20, 1993
    Assignee: Warner-Lambert Company
    Inventor: Rex A. Jennings
  • Process for cyclic amino acid anticonvulsant compounds
    Patent number: 5132451
    Abstract: An improved process for the preparation of cyclic amino acids by a novel synthesis is described where a dinitrile derivative is converted in two steps to the desired products, as well as valuable intermediates used in the process.
    Type: Grant
    Filed: August 10, 1990
    Date of Patent: July 21, 1992
    Assignee: Warner-Lambert Company
    Inventors: Rex A. Jennings, Don R. Johnson, Ronald E. Seamans, James R. Zeller
  • Podophyllotoxin purification process
    Patent number: 5057616
    Abstract: Podophyllotoxin is recovered from podophyllum resin with improved efficiency by adsorbing impurities out of a solution using a solid adsorbent, preferably alumina. This improvement finds application in an overall process for purifying podophyllotoxin from podophyllum resin in which the podophyllotoxin is first crystallized from the podophyllum resin, the crystals so formed are dissolved and subjected to the solid adsorbent treatment, crystals are then recovered and optionally recrystallized and dried to give the desired product.
    Type: Grant
    Filed: September 29, 1989
    Date of Patent: October 15, 1991
    Assignee: Oclassen Pharmaceuticals, Inc.
    Inventors: Rex A. Jennings, Jay F. Stearns