Patents by Inventor Rex Parker

Rex Parker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
    Publication number: 20030225091
    Abstract: Compounds that are dual aP2/k-FABP inhibitors are provided having the formula 1
    Type: Application
    Filed: November 15, 2002
    Publication date: December 4, 2003
    Inventors: David R. Magnin, Richard B. Sulsky, Jeffrey A. Robl, Thomas J. Caulfield, Rex A. Parker
  • Method for treating atherosclerosis employing an aP2 inhibitor and combination
    Publication number: 20020035064
    Abstract: A method is provided for treating atherosclerosis and related diseases, employing an aP2 inhibitor or a combination of an aP2 inhibitor and another antiatherosclerotic agent, for example, an HMG CoA reductase inhibitor such as pravastatin.
    Type: Application
    Filed: July 13, 2001
    Publication date: March 21, 2002
    Inventors: Jeffrey A. Robl, Rex A. Parker, Scott A. Biller, Haris Jamil, Bruce L. Jacobson, Krishna Kodukula
  • Aminobiphenyl-4-ol anti-atherosclerotic compounds and method
    Patent number: 5488068
    Abstract: Antiatherosclerotic compounds are provided which have the structure ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen, lower alkyl, or arylalkyl, at least one of R.sup.1 and R.sup.2 being other than hydrogen, and R.sup.3, R.sup.4 and R.sup.5 are independently hydrogen, lower alkyl, lower alkenyl, halo, alkoxy, aryl or arylalkyl. A method for treating atherosclerosis employing the above compounds is also provided.
    Type: Grant
    Filed: August 18, 1994
    Date of Patent: January 30, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Rex A. Parker, Scott A. Biller
  • Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
    Patent number: 5348974
    Abstract: This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. The isolation of these tocotrienols from natural sources and their chemical synthesis is disclosed. The present invention also relates to prodrugs and pharmaceutical compositions of gamma-tocotrienol, delta-tocotrienol and tocotrienol and uses thereof.
    Type: Grant
    Filed: February 10, 1993
    Date of Patent: September 20, 1994
    Assignee: Bristol-Myers Squibb Company
    Inventors: John J. Wright, Bradley C. Pearce, Rex Parker, Asaf A. Qureshi
  • Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
    Patent number: 5217992
    Abstract: This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. [The isolation of these tocotrienols from natural sources and their chemical synthesis is disclosed.] The chemical synthesis of these tocotrienols is disclosed. The present invention also relates to prodrugs and pharmaceutical compositions of gamma-tocotrienol, delta-tocotrienol and tocotrienol and uses thereof.
    Type: Grant
    Filed: September 17, 1990
    Date of Patent: June 8, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: John J. Wright, Bradley C. Pearce, Rex Parker, Asaf A. Qureshi