Abstract: A method of manufacturing a forming tool. The forming tool may include at least one die having a perimeter wall and a profile panel. At least a portion of the die may be manufactured using an additive manufacturing process. For instance, the profile panel may be manufactured using an additive manufacturing process or the profile panel and additional portions of the die, such as the perimeter wall, may be manufactured using an additive manufacturing process.

Abstract: A method for forming polyurethane foams for vehicle seat components in a molding apparatus is provided. The method includes a step of directing one or more polyol compositions into a mold. Each of the one or more polyol compositions includes a polyol, water, and a catalyst. The method also includes a step of directing an isocyanate composition into the mold, the isocyanate composition including one or more isocyanates. The one or more polyol compositions and the one or more isocyanates are combined into a reaction composition that forms a foamed vehicle seat component. Characteristically, the mold has a shape that defines a foamed vehicle seat component. Characteristically, either the one or more polyol compositions and/or the isocyanate composition includes a liquid antimicrobial agent that is a liquid at temperatures above 10° C.

Abstract: An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an automated actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

Abstract: A catalyst composition for catalyzing a polyurethane forming reaction includes a gelling catalyst and a blowing catalyst selected such that the resulting polyurethane foam has a low level of volatile and/or malodorous material in it. The gelling catalysts are selected from tertiary aminoalkyl substituted primary or secondary amines; and the blowing catalysts are selected from bis(aminoalkyl) ethers comprising alkanol moieties, primary amine moieties, or ureido moieties derived from such primary amine moieties.

Abstract: A catalyst composition for catalyzing a polyurethane forming reaction includes a gelling catalyst and a blowing catalyst selected such that the resulting polyurethane foam has a low level of volatile and/or malodorous material in it. The gelling catalysts are selected from tertiary aminoalkyl substituted primary or secondary amines; and the blowing catalysts are selected from bis(aminoalkyl) ethers comprising alkanol moieties, primary amine moieties, or ureido moieties derived from such primary amine moieties.

Abstract: Novel acid-blocked amine catalysts and their use in the preparation of polyurethanes. The acid-blocked amine catalysts have the general structure shown below: wherein A is the residue of an organic acid anhydride; R1 is H or C1 to C6 alkyl; R2 is H or C1 to C6 alkyl; n is an integer of 0 to 10; and B is a compound containing a protonated amine and one or more primary amine, secondary amine, or tertiary amine groups.

Abstract: Novel acid-blocked amine catalysts and their use in the preparation of polyurethanes.

Abstract: Novel acid-blocked amine catalysts and their use in the preparation of polyurethanes. The acid-blocked amine catalysts have the general structure shown below: wherein A is the residue of an organic acid anhydride; R1 is H or C1 to C6 alkyl; R2 is H or C1 to C6 alkyl; n is an integer of 0 to 10; and B is a compound containing a protonated amine and one or more primary amine, secondary amine, or tertiary amine groups.