Patents by Inventor Reza Izadpanah

Reza Izadpanah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and composition for early detection of malignancies
    Publication number: 20230250428
    Abstract: A method and composition for treating a subject having a difficult to treat tumor is described. A TRAF3IP2 silencer is administered to the subject, preferably together with other synergistic medication such as chemotherapy, immunotherapies or other anticancer medication, that given alone are less or not successful for treating this special tumor, to increase relapse free survival. The TRAF3IP2 silencer in conjunction with other synergistic medication can additionally be used to effectively treat or prevent metastasis in a subject having an otherwise difficult to treat tumor.
    Type: Application
    Filed: February 7, 2023
    Publication date: August 10, 2023
    Inventors: Eckhard U. ALT, Reza IZADPANAH, Amin IZADPANAH
  • Small tissue CCR5MSCs for treatment of HIV
    Patent number: 10918672
    Abstract: A method of curing (or at least treating) HIV, by obtaining small tissue mesenchymal stem cells (stMSC) from adipose tissue of a patient with HIV or from a syngeneic donor or an immuno-compatible donor, wherein said stMSC are i) 4-6 ?m in diameter, ii) pluripotent, and iii) have CD11b?, CD34?, CD45?, CD 29, CD 49, Oct 4 and SSEA 4 surface markers when harvested. Preferred sources are autologous adipose tissue. Next those stMSCs are gene edited to provide CCR5? stMSCs and optionally amplified by growth in culture and/or by cell selection for gene edited stMSCs and then re-introducing into the patient. Preferably, the CCR5? stMSCs will re-populate the patient with stem cells that can no longer act as latent HIV reservoirs and can differentiate into immune cells that are HIV resistant. If desired, the patient can be first treated, e.g., by radiation, to destroy the bone marrow cells before the re-introduction.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: February 16, 2021
    Assignee: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
    Inventors: Stephen E. Braun, Reza Izadpanah, Eckhard Alt
  • Preventing tumor development and metastasis
    Patent number: 10538767
    Abstract: Treatment of tumors, especially breast cancer or glioblastoma tumors, by silencing RAB27A and/or TRAF3IP2, compositions and methods for same.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: January 21, 2020
    Assignee: The Administrators of the Tulane Educational Fund
    Inventors: Eckhard Alt, Reza Izadpanah
  • PREVENTING TUMOR DEVELOPMENT AND METASTASIS
    Publication number: 20190078092
    Abstract: Treatment of tumors, especially breast cancer or glioblastoma tumors, by silencing RAB27A and/or TRAF3IP2, compositions and methods for same.
    Type: Application
    Filed: November 26, 2018
    Publication date: March 14, 2019
    Inventors: Eckhard Alt, Reza Izadpanah
  • Preventing tumor development and metastasis
    Patent number: 10137143
    Abstract: Treatment of tumors, especially breast cancer or glioblastoma tumors, by silencing RAB27A and/or TRAF3IP2, compositions and methods for same.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: November 27, 2018
    Assignee: The Administrators of the Tulane Educational Fund
    Inventors: Eckhard Alt, Reza Izadpanah
  • Derivation of hematopoietic cells from adult mesenchymal stem cells
    Patent number: 9447379
    Abstract: Methods and compositions for differentiating tissue resident multipotent mesenchmal stromal cells (MSCs) such as adipose tissue resident MSCs into a hematopoietic lineage are described.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: September 20, 2016
    Inventors: Reza Izadpanah, Eckhard Alt
  • DERIVATION OF HEMATOPOIETIC CELLS FROM ADULT MESENCHYMAL STEM CELLS
    Publication number: 20130190729
    Abstract: Methods and compositions for differentiating tissue resident multipotent mesenchmal stromal cells (MSCs) such as adipose tissue resident MSCs into a hematopoietic lineage are described.
    Type: Application
    Filed: February 28, 2011
    Publication date: July 25, 2013
    Inventors: Reza Izadpanah, Eckhard Alt