Abstract: An oral appliance for treating sleep apnea in a user includes a mouthpiece configured for being positioned in an oral cavity of the user, a processor, and at least one sensor coupled to the mouthpiece. According to an aspect, the processor may be configured to detect a condition of a user based on data generated by the at least one sensor. Additionally, the sensor may include at least one of a sound measuring device, an inertial measurement unit, a pulse oximeter, or an electroencephalogram.

Abstract: A system for detecting target molecules in a patient's saliva includes an oral appliance and a cassette removably coupled to the oral appliance. According to an aspect, the cassette includes a microtubule including a collection portion. A detector is configured to transmit light through the removable cassette, measure the amount of light transmitted through the microtubule, determine an absorption or scattering amount of the light, and determine whether the target molecules are present in the patient's saliva based on the absorption or scattering amount of the light.

Abstract: An oral appliance for treating sleep apnea in a user includes a mouthpiece configured for being positioned in an oral cavity of the user, and at least one pulse oximeter coupled to the mouthpiece. According to an aspect, the pulse oximeter is configured to monitor actual oxygen saturation of hemoglobin of the user when the oral appliance is positioned in the oral cavity of the user.

Abstract: A reusable needle handling apparatus is described. The needle handling apparatus is configured for receiving at least a portion of a syringe assembly including at least a needle, a needle cap, and a syringe hub. The needle handling apparatus includes a first clamping mechanism having a plurality of pinch rollers. According to an aspect, the pinch rollers are configured to clamp the needle cap, and to automatically unscrew the needle from the syringe hub, so that the needle is safely and automatically removed from the syringe hub.

Abstract: An oral appliance for treating sleep apnea in a user includes a mouthpiece configured for being positioned in an oral cavity of the user, and at least one pulse oximeter attached to the mouthpiece. According to an aspect, the pulse oximeter is configured to monitor actual oxygen saturation levels of hemoglobin of the user when the oral appliance is positioned in the oral cavity of the user. The oral appliance may include an additional sensor attached to the mouthpiece that includes at least one of an airflow sensor, a pressure sensor, a noise detector, and an actigraphy sensor.

Abstract: An oral appliance for treating sleep apnea in a user includes a mouthpiece configured for being positioned in an oral cavity of the user, and at least one pulse oximeter attached to the mouthpiece. According to an aspect, the pulse oximeter is configured to monitor actual oxygen saturation levels of hemoglobin of the user when the oral appliance is positioned in the oral cavity of the user. The oral appliance may include an additional sensor attached to the mouthpiece that includes at least one of an airflow sensor, a pressure sensor, a noise detector, and an actigraphy sensor.

Abstract: A personal protective equipment includes a substrate, and an anti-microbial substance is positioned in the substrate. The anti-microbial substance includes tourmaline. The personal protective equipment may include a face mask or a garment having a nonwoven body. The anti-microbial substance is positioned on or in the nonwoven body.

Abstract: An oral appliance for treating sleep apnea in a user includes a mouthpiece configured for being positioned in an oral cavity of the user, and at least one pulse oximeter attached to the mouthpiece. According to an aspect, the pulse oximeter is configured to monitor actual oxygen saturation levels of hemoglobin of the user when the oral appliance is positioned in the oral cavity of the user. The oral appliance may include an additional sensor attached to the mouthpiece that includes at least one of an airflow sensor, a pressure sensor, a noise detector, and an actigraphy sensor.

Abstract: An oral device for treating obstructive sleep apnea is generally described. In an embodiment, the oral device includes an anchoring member, a lip sealing member and an air transmission member configured to receive and transmit air to a user. The air transmission member may divide and distribute the air to multiple locations within the user's oral cavity. The anchoring member is configured to receive a dentition of the user. According to some embodiments, the lip sealing member may include an inner lip seal and an outer lip seal. The inner and outer lip seals are customized to the user's lips and may be slidably received on the air transmission member. Thus, the lip sealing member is configured to provide a substantially airtight seal for the user's lips, thereby limiting and/or inhibiting air exchange between the user's lips.

Abstract: An orthodontic expansion device includes a pair of opposed lateral portions, each of which includes a molar band shaped to be positioned on molars or other teeth of a patient. A palate frame extends obliquely from the molar band. The device further includes a tensioned tensioning assembly positioned between the pair of opposed lateral portions that applies an outward pressure on the palate of the patient. The tensioning assembly is at least partially detachable for adjusting the tension of the device. As the palate expands, and the tension in the device relaxes, the tensioning assembly can readily be detached, retensioned, and reattached.

Abstract: A strut assembly for an oral appliance for the treatment of sleep apnea in a user includes a unitary body formed from a polymeric material. The unitary body includes an anterior end and a posterior end. A posterior projection is connected to the posterior end and an anterior projection is connected the anterior end. The unitary body, the posterior ball and the anterior protrusion integrally and monolithically formed.

Abstract: A mouthpiece for being worn on the upper dentition of a user includes electrodes and a microprocessor that operate as an electroencephalograph for detecting electrical activity in the user's brain. The mouthpiece may be useful in a variety of applications, such as athletics, gaming, and personal hobbies.

Abstract: An oral appliance for the treatment of sleep disorders, such as obstructive sleep apnea, in a user is presented. The oral appliance may include a mouthpiece configured to receive a user's dentition. The mouthpiece may include an oxygen sensor, a pressure sensor, an airflow sensor, an actigraphy sensor, a noise detector, and at least one stimulator for providing stimulation to a user's tongue in the event of decreased oxygen saturation levels, increased pressure applied to occlusal surfaces of the user's dentition, decreased actual airflow levels and/or increased noise levels. The mouthpiece or a separate portion of the mouthpiece may be provided with an EEG sensor to determine sleep state based on EEG rhythms. The mouthpiece may be provided with pharmaceutical compound reservoirs that deliver pharmaceutical compounds to the oral mucosa of the user, which compounds treat symptoms of sleep apnea.

Abstract: An oral appliance for the treatment of obstructive sleep apnea includes a mouthpiece configured for being received in an oral cavity of a user. The mouthpiece may include a pulse oximeter, a pressure sensor, an airflow sensor, an actigraphy sensor, a noise detector, and at least one stimulator for providing stimulation to a user's tongue in the event of decreased oxygen saturation levels, increased pressure applied to occlusal surfaces of the user's dentition, decreased actual airflow levels and/or increased noise levels. A microprocessor receives data from the oxygen sensor, pressure sensor, airflow sensor, actigraphy sensor and noise detector, and activates the at least one stimulator.

Abstract: A personal protective equipment includes a substrate, and an anti-microbial substance is positioned in the substrate. The anti-microbial substance includes tourmaline. The personal protective equipment may include a face mask or a garment having a nonwoven body. The anti-microbial substance is positioned on or in the nonwoven body.

Abstract: A jig assembly may include an upper jig including an upper bite block for receiving upper teeth, a lower jig including a lower bite block for receiving lower teeth, and a fastener for securing each of the upper jig and the lower jig in a fixed position relative to one another. A jig assembly may include a first jig and a second jig coupled to the first jig. The first jig and the second jig may be switchable between a first configuration in which the first jig is slidable relative to the second jig in a first direction and a second configuration in which the first jig and the second jig are fixed relative to each other in the first direction.

Abstract: An intraoral device includes a mouthpiece for receiving a dentition of a user. The intraoral appliance further includes an oxygen sensor and an infrared radiation emitter. The oxygen sensor may include a photoplethysmography sensor. The intraoral device may further include a thermoelectric power source to supply power to the infrared radiation emitter and the photoplethysmography sensor.

Abstract: An oral appliance for the treatment of sleep disorders, such as obstructive sleep apnea, in a user is presented. The oral appliance may include a mouthpiece configured to receive a user's dentition. The mouthpiece may include an oxygen sensor, a pressure sensor, an airflow sensor, an actigraphy sensor, a noise detector, and at least one stimulator for providing stimulation to a user's tongue in the event of decreased oxygen saturation levels, increased pressure applied to occlusal surfaces of the user's dentition, decreased actual airflow levels and/or increased noise levels. The mouthpiece may be provided with pharmaceutical compound reservoirs that deliver pharmaceutical compounds to the oral mucosa of the user, which compounds treat symptoms of sleep apnea. The mouthpiece may further include a microprocessor that receives data from the oxygen sensor, pressure sensor, airflow sensor, actigraphy sensor and noise detector, and activates the at least one stimulator and/or pharmaceutical compound reservoirs.

Abstract: A provisional oral appliance for the temporary treatment of sleep apnea includes a pair of trays for receiving the user's upper and lower teeth, and a pair of adjustable, fixed-length strut assemblies pivotably connected to the upper tray and lower tray. An adjustable jig for positioning the upper and lower teeth of the user relative to one another may be used in making the oral appliance.