Abstract: The present invention is in the field of personal care compositions; in particular skin lightening compositions. It is believed that niacinamide reduces the melanosome transfer from melanocytes to keratinocytes thereby bringing about skin lightening. However, niacinamide is known to have little or no effect directly on the melanin content in the melanocytes. Thus a composition with multiple modes of action, that combines the reduction of melanosome transfer and the reduction of melanin content in the melanocytes remains to be desired. It is therefore an object of the present invention to provide a composition with synergistic amounts of picolinamide and niacinamide, providing improved melanosome transfer inhibition. It has been found that a synergistic skin lightening effect is obtained when niacinamide is combined with its isomer, picolinamide.

Abstract: Disclosed is a cosmetic composition comprising: (i) at least one pyridine compound of Formula I or II: where, in said Formula I and in said Formula II, X is S or O; R, R1, R2, R3 are either —H, —SH, —OH or a CMS saturated or unsaturated, =linear, branched or cyclic hydrocarbon group; Y is —H, —SH or CMS saturated or unsaturated, linear, branched or cyclic hydrocarbon group; (ii) an alkyl substituted resorcinol; and, (iii) a dermatologically acceptable base. Also disclosed is use of a pyridine compound of Formula I or II in the preparation of a cosmetic composition which provides enhanced TDD of an alkyl substituted resorcinol.

Abstract: The present invention is in the field of personal care compositions; in particular skin lightening compositions. It is believed that niacinamide reduces the melanosome transfer from melanocytes to keratinocytes thereby bringing about skin lightening. However, niacinamide is known to have little or no effect directly on the melanin content in the melanocytes. Thus a composition with multiple modes of action, that combines the reduction of melanosome transfer and the reduction of melanin content in the melanocytes remains to be desired. It is therefore an object of the present invention to provide a composition with synergistic amounts of picolinamide and niacinamide, providing improved melanosome transfer inhibition. It has been found that a synergistic skin lightening effect is obtained when niacinamide is combined with its isomer, picolinamide.

Abstract: The present invention relates to a personal care composition for topical application having a skin lightening application. It is an object of the present invention to provide for a personal care composition that comprises fractions obtained from natural sources that gives enhanced skin lightening as compared to known fractions from natural sources.

Abstract: The present invention relates to a personal care composition for topical application having a skin lightening application. It is an object of the present invention to provide for a personal care composition that comprises fractions obtained from natural sources that gives enhanced skin lightening as compared to known fractions from natural sources.