Abstract: Disclosed herein is a shielded chamber system for diagnostic evaluation of a condition of an individual. The shielded chamber system comprises an enclosure comprising a plurality of walls, a wall comprising a plurality of layers of magnetic shielding material. The shielded chamber system also comprises one or more application-specific modular components configured to be inserted within the enclosure, wherein an application-specific modular component comprises an array of biomagnetic field sensors configured to sense an electromagnetic field associated with the individual and generate electromagnetic field data therefrom. Finally, the shielded chamber system comprises one or more holes or passthroughs inserted into at least one wall of the plurality of walls, wherein a hole or passthrough is configured for passing electrical or data cabling into and out of the enclosure.

Abstract: The present disclosure provides a biomagnetic field sensor system for diagnostic evaluation of a cardiac condition of an individual. The biomagnetic field sensor system may comprise an array of biomagnetic field sensors configured to sense an electromagnetic field associated with a heart of the individual and generate electromagnetic field data therefrom; a computer processor coupled to the array of biomagnetic field sensors; a memory configured to store the electromagnetic field data generated by the array of biomagnetic field sensors; and a non-transitory computer-readable medium encoded with a computer program including instructions that, when executed by the computer processor, cause the computer processor to receive the electromagnetic field data, and generate a diagnostic evaluation of a cardiac condition of the individual based at least in part on an analysis of the electromagnetic field data.

Abstract: In an aspect, the present disclosure provides a method comprising: (a) identifying a first negative and positive electromagnetic dipoles in a first electromagnetic field map associated with a heart of the individual at a first time; (b) identifying a second negative and positive electromagnetic dipoles in a second electromagnetic field map associated with the heart of the individual at a second time; (c) determining a first angle based on the first negative and positive electromagnetic dipoles; (d) determining a second angle based on the second negative and positive electromagnetic dipoles; and (e) determining a presence, an absence, or a likelihood of coronary artery disease in the individual, based at least in part on (i) whether the first angle differs from the second angle by at least 100 degrees, or (ii) whether there is a presence of a third electromagnetic dipole in the first or the second electromagnetic field map.

Abstract: The present disclosure provides a biomagnetic field sensor system for diagnostic evaluation of a cardiac condition of an individual. The biomagnetic field sensor system may comprise an array of biomagnetic field sensors configured to sense an electromagnetic field associated with a heart of the individual and generate electromagnetic field data therefrom; a computer processor coupled to the array of biomagnetic field sensors; a memory configured to store the electromagnetic field data generated by the array of biomagnetic field sensors; and a non-transitory computer-readable medium encoded with a computer program including instructions that, when executed by the computer processor, cause the computer processor to receive the electromagnetic field data, and generate a diagnostic evaluation of a cardiac condition of the individual based at least in part on an analysis of the electromagnetic field data.

Abstract: The present disclosure provides a biomagnetic field sensor system for diagnostic evaluation of a cardiac condition of an individual. The biomagnetic field sensor system may comprise an array of biomagnetic field sensors configured to sense an electromagnetic field associated with a heart of the individual and generate electromagnetic field data therefrom; a computer processor coupled to the array of biomagnetic field sensors; a memory configured to store the electromagnetic field data generated by the array of biomagnetic field sensors; and a non-transitory computer-readable medium encoded with a computer program including instructions that, when executed by the computer processor, cause the computer processor to receive the electromagnetic field data, and generate a diagnostic evaluation of a cardiac condition of the individual based at least in part on an analysis of the electromagnetic field data.

Abstract: Described herein are methods, software, systems and devices that include a set of hardware and software tools employed to rapidly rule-out patients that present to, for example, the emergency room and observation clinical decision units with chest pain, for coronary artery disease.