Patents by Inventor Rheal Towner

Rheal Towner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADJUVANT CHEMOTHERAPY FOR ANAPLASTIC GLIOMAS
    Publication number: 20140200234
    Abstract: The present invention involves the use of 2,4-disulfonyl phenyl tert-butyl nitrone (2,4-ds-PBN) in the treatment and prevention of gliomas. The 2,4-ds-PBN may be used alone or combined with other traditional chemo- and radiotherapies and surgery, to treat or prevent glioma occurrence, recurrence, spread, growth, metastasis, or vascularization.
    Type: Application
    Filed: January 21, 2014
    Publication date: July 17, 2014
    Applicant: OKLAHOMA MEDICAL RESEARCH FOUNDATION
    Inventors: Rheal A. TOWNER, Robert A. FLOYD
  • METHODS FOR TREATING BRAIN INJURY
    Publication number: 20140187631
    Abstract: The treatment options for treating blast-induced and noise-induced traumatic brain injury and tinnitus are limited. Thus, the current invention provides methods for treating traumatic brain injury and tinnitus. The methods involve administering a pharmaceutically effective amount of a composition comprises 2,4-disulfonyl ?-phenyl tertiary butyl nitrone and N-acetylcysteine (NAC).
    Type: Application
    Filed: February 3, 2012
    Publication date: July 3, 2014
    Inventors: Richard D. Kpoke, Robert A. Floyd, Rheal Towner
  • Adjuvant chemotherapy for anaplastic gliomas
    Patent number: 8633249
    Abstract: The present invention involves the use of 2,4-disulfonyl phenyl tert-butyl nitrone (2,4-ds-PBN) in the treatment and prevention of gliomas. The 2,4-ds-PBN may be used alone or combined with other traditional chemo- and radiotherapies and surgery, to treat or prevent glioma occurrence, recurrence, spread, growth, metastasis, or vascularization.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: January 21, 2014
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Rheal A. Towner, Robert A. Floyd
  • Adjuvant Chemotherapy For Anaplastic Gliomas
    Publication number: 20100076009
    Abstract: The present invention involves the use of 2,4-disulfonyl phenyl tert-butyl nitrone (2,4-ds-PBN) in the treatment and prevention of gliomas. The 2,4-ds-PBN may be used alone or combined with other traditional chemo- and radiotherapies and surgery, to treat or prevent glioma occurrence, recurrence, spread, growth, metastasis, or vascularization.
    Type: Application
    Filed: September 2, 2009
    Publication date: March 25, 2010
    Inventors: Rheal A. Towner, Robert A. Floyd
  • Metabolite detection using magnetic resonance
    Publication number: 20080081375
    Abstract: Methods using magnetic resonance, such as nuclear magnetic resonance (NMR) spectroscopy or magnetic resonance imaging (MRI), are provided for detecting metabolites in a sample. The methods are useful for the diagnosis or prognosis of a disease such as cancer and can also be used to determine or monitor a treatment protocol. The methods are useful in characterizing speciation in biological samples where mixtures are often encountered and chemical shifts of the same structural group of similar molecules can produce complicated overlapping resonances.
    Type: Application
    Filed: October 3, 2007
    Publication date: April 3, 2008
    Applicant: Oklahoma Medical Research Foundation
    Inventors: Yasvir A. Tesiram, Rheal A. Towner
  • ADJUVANT CHEMOTHERAPY FOR ANAPLASTIC GLIOMAS
    Publication number: 20070032453
    Abstract: The present invention involves the use of nitrone free radical trapping agents in the treatment and prevention of gliomas. The agents may be used alone or combined with other traditional chemo- and radiotherapies and surgery, to treat or prevent glioma occurrence, recurrence, spread, growth, metastasis, or vascularization.
    Type: Application
    Filed: July 28, 2006
    Publication date: February 8, 2007
    Inventors: Rheal Towner, Yashige Kotake, Robert Floyd