Patents by Inventor Rhett Klein

Rhett Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070208020
    Abstract: The invention provides compounds and methods for inhibition of kinases, more specifically p70S6 kinases. The invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration, chemoinvasion and metabolism. Compounds of the invention inhibit, regulate and/or modulate kinase receptor signal transduction pathways related to the changes in cellular activities as mentioned above, and the invention includes compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.
    Type: Application
    Filed: October 22, 2004
    Publication date: September 6, 2007
    Inventors: Wei Cheng, Erick Co, Moon Kim, Rhett Klein, Donna Le, Amy Suhako, John Nuss, Wei Xu
  • Publication number: 20060122171
    Abstract: The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides oxindole derivatives which inhibit, regulate and/or modulate kinase receptor, particularly VEGF receptor 2 (Flk-1/KDR), FGFR1, and PDGFR (alpha and beta), signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.
    Type: Application
    Filed: November 14, 2003
    Publication date: June 8, 2006
    Inventors: Wei Xu, Lynne Canne Bannen, Samuel Brown, Erick Co, John Nuss, Moon Kim, Rhett Klein, Donna Lee, Amy Tsuhako, Morrison Mac, Jason Parks, Zhaoyang Wen, Wei Cheng