Patents by Inventor Rhodes Technologies

Rhodes Technologies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130102784
    Abstract: The present disclosure provides improved methods for N-dealkylation of tertiary amines, including methods for N-demethylation of alkaloids and opioids, in which the dealkylation reaction is carried out in a solvent comprising a tertiary alcohol. The present disclosure also provides improved processes for preparing semi-synthetic opioids that incorporate the disclosed methods for N-dealkylation of tertiary amines.
    Type: Application
    Filed: December 11, 2012
    Publication date: April 25, 2013
    Applicant: Rhodes Technologies
    Inventor: Rhodes Technologies
  • Publication number: 20130102780
    Abstract: The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.
    Type: Application
    Filed: December 11, 2012
    Publication date: April 25, 2013
    Applicant: Rhodes Technologies
    Inventor: Rhodes Technologies