Patents by Inventor Rhona Sinclair

Rhona Sinclair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process For The Production Of (Alkoxycarbonylamino)alkyl Sulfonates
    Publication number: 20100041911
    Abstract: There is provided a process for the preparation of a compound of formula I, which process comprises: (a) reaction of a compound of formula II, HO-D-NH2 II with a compound of formula III, followed by (b) reaction of the intermediate of formula IV thereby formed, IV with base and a compound of formula V, R2S(O)2L2 V, wherein the intermediate of formula IV is not isolated, and wherein D, R1, R2, L1 and L2 have meanings given in the description.
    Type: Application
    Filed: June 12, 2006
    Publication date: February 18, 2010
    Applicant: ASTRAZENECA AB
    Inventors: David Cladingboel, Adam Herring, Rhona Sinclair
  • Novel Process 1
    Publication number: 20080064884
    Abstract: The present invention relates to a novel process for the preparation of compounds of formula (I) wherein X, Q, R1 and R2 are as defined in the specification, the compounds being useful in the preparation of therapeutic agents. The invention further relates to novel intermediates useful in the preparation of the therapeutic agents.
    Type: Application
    Filed: May 3, 2007
    Publication date: March 13, 2008
    Applicant: AstraZeneca AB
    Inventors: Debra Ainge, Philip Cornwall, Duncan Michael Gill, Vinod Kumar, Luis Manuel Vaz, Philip O'Keefe, Rhona Sinclair, Edward Laurence Way
  • New Process For The Preparation Of Oxabispidines
    Publication number: 20070197519
    Abstract: There is provided a process for the preparation of a compound of formula (I): which process comprises reaction of a compound of formula (TI): with either a compound of formula (ITT): or acrylamide, followed, in the latter case, by reaction of the resulting intermediate of formula (IV): with an alcohol of formula R2?OH and an agent that promotes, or agents that in combination promote, rearrangement and oxidation of the compound of formula IV to an intermediate isocyanate, which may then react with the alcohol of formula R2?OH, and wherein R1, R2 and R16 have meanings given in the description.
    Type: Application
    Filed: December 19, 2006
    Publication date: August 23, 2007
    Applicant: ASTRAZENECA AB
    Inventors: Lal Cheema, David Cladingboel, Rhona Sinclair
  • Process for the preparation of oxabispidines
    Patent number: 7169921
    Abstract: There is provided a process for the preparation of a compound of formula (I): which process comprises reaction of a compound of formula (II): with either a compound of formula (III): or acrylamide, followed, in the latter case, by reaction of the resulting intermediate of formula (IV): with an alcohol of formula R2—OH and an agent that promotes, or agents that in combination promote, rearrangement and oxidation of the compound of formula IV to an intermediate isocyanate, which may then react with the alcohol of formula R2—OH, and wherein R1, R2 and R16 have meanings given in the description
    Type: Grant
    Filed: April 12, 2002
    Date of Patent: January 30, 2007
    Assignee: Astrazeneca AB
    Inventors: Lal Cheema, David Cladingboel, Rhona Sinclair
  • Process for the preparation of oxabispidines
    Publication number: 20040181060
    Abstract: There is provided a process for the preparation of a compound of formula (I): which process comprises reaction of a compound of formula (II): with either a compound of formula (III): or acrylamide, followed, in the latter case, by reaction of the resulting intermediate of formula (IV): with an alcohol of formula R2—OH and an agent that promotes, or agents that in combination promote, rearrangement and oxidation of the compound of formula IV to an intermediate isocyanate, which may then react with the alcohol of formula R2—OH, and wherein R1, R2 and R16 have meanings given in the description.
    Type: Application
    Filed: April 22, 2004
    Publication date: September 16, 2004
    Inventors: Lal Cheema, David Cladingboel, Rhona Sinclair