Patents by Inventor Rhonda L. Ackley

Rhonda L. Ackley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoassay for human restrictin
    Patent number: 5635360
    Abstract: Human restrictin proteins and nucleic acid sequences encoding them are provided. Antibodies which recognize human restrictin in human brain are disclosed. In the human brain, restrictin occurs as two major polypeptides of 180 and 160 kD located in fiber tracts. These polypeptides are similar to those seen in rat brain. Surprisingly, restrictin has also been found in the peripheral nerves of rats and humans The antibodies also detect a 170 kD polypeptide in MATRIGEL, an extracellular matrix product of rat EHS sarcoma cells widely used as a tissue culture substrate. Monoclonal antibodies to human restrictin and assays using the human restrictin protein, antibodies and DNA sequences are also provided.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: June 3, 1997
    Assignee: Becton, Dickinson and Company
    Inventors: Robert A. Reid, Rhonda L. Ackley, John J. Hemperly
  • Human restrictin and nucleic acid sequences
    Patent number: 5591583
    Abstract: Human restrictin proteins and nucleic acid sequences encoding them are provided. Antibodies which recognize human restrictin in human brain are disclosed. In the human brain, restrictin occurs as two major polypeptides of 180 and 160 kD located in fiber tracts. These polypeptides are similar to those seen in rat brain. Surprisingly, restrictin has also been found in the peripheral nerves of rats and humans. The antibodies also detect a 170 kD polypeptide in MATRIGEL, an extracellular matrix product of rat EHS sarcoma cells widely used as a tissue culture substrate. Monoclonal antibodies to human restrictin and assays using the human restrictin protein, antibodies and DNA sequences are also provided.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: January 7, 1997
    Assignee: Becton, Dickinson and Company
    Inventors: Robert A. Reid, Rhonda L. Ackley, John J. Hemperly