Abstract: The present invention provides a pharmaceutical composition for prevention or treatment of a stress disease and depression, the pharmaceutical composition be safely useable without toxicity and side effects by using an extract of leaves of Vaccinium bracteatum Thunb., which is natural resource of Korea, so that the reduction of manufacturing and production costs and the import substitution and export effects can be expected through the replacement of a raw material for preparation with a plant inhabiting in nature.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery using a positive electrode containing the positive electrode active material. More particularly, the present invention relates to a positive electrode active material that is able to solve a problem of increased resistance according to an increase in Ni content by forming a charge transport channel in a lithium composite oxide and a lithium secondary battery using a positive electrode containing the positive electrode active material.

Abstract: The present invention relates to a method for predicting the reactivity of a cancer-targeted therapeutic agent, in which various types of target proteins targeted by a cancer-targeted therapeutic agent are simultaneously quantified through triple quadrupole mass spectrometry. The inventors of the present invention carefully selected peptide sequences with high selectivity in nanoflow liquid chromatography-triple quadrupole mass spectrometry, in response to clinical needs, and optimized peptide combinations and experimental conditions to enable multiple peptide quantification.

Abstract: A prelithiated negative electrode, and a secondary battery including a prelithiated electrode, including a negative electrode current collector; and a negative electrode active material layer present on at least one surface of the negative electrode current collector. The negative electrode active material layer includes high-capacity artificial graphite having no carbon coating. The negative electrode active material layer is prelithiated, and the content of lithium intercalated to the prelithiated negative electrode active material layer is 3% to 5% based on the lithium content intercalated when the negative electrode is charged to 100%.

Abstract: A semiconductor device comprises a substrate including first and second regions; a plurality of conductive line structures disposed over the substrate; a plurality of conductive contact plugs formed between the conductive line structures disposed over the first region of the substrate; and a plurality of dummy dielectric plugs disposed over the second region of the substrate.

Abstract: A display apparatus including a display panel, a light source configured to emit light, and a light guide disposed on the light source and covering a side of the light source, the light source including a substrate, a light emitter including a light emitting stacked layer and disposed on the substrate, a light blocking layer disposed on a side surface of the light emitting stacked layer, and a reflector disposed between the substrate and the light guide, in which the light emitter has a first length direction and a second length direction, wherein orientation angles of the light emitter in the first and second length directions are different from each other, the substrate includes a first pad electrode and second pad electrode electrically connected to the light emitter, and the first and second pad electrodes are spaced apart from each other by at least 50 ?m.

Abstract: A battery mounting structure for a vehicle is provided to include a case having a first internal member that is disposed to be spaced parallel to an upper side of a lower panel of the case and a second internal member that is disposed perpendicular to the first internal member, and configured to accommodate a plurality of battery modules therein using the first internal member and the second internal member. An outer side member is provided in a shape protruding toward the outside on an outer side of the case. The battery modules are disposed in a stacking direction of battery cells that is parallel to a longitudinal direction of the first internal member.

Abstract: A dynamic hashing apparatus includes a processor configured to obtain a target segment based on at least a part of a key value of an insertion request, compute a hash value by applying a remapping function corresponding to the obtained target segment to an input value based on the key value, and update the remapping function by adjusting a slope of the remapping function in response to the key value not being insertable into a target bucket selected based on at least a part of the computed hash value from among buckets included by the target segment.

Abstract: A semiconductor device includes: a semiconductor substrate; a plurality of bit line structures spaced apart from each other over the semiconductor substrate and each including a stacked structure of a bit line and a bit line hard mask; a contact pad positioned over the semiconductor substrate between the neighboring bit line structures; a contact structure including a stacked structure of a first contact formed over the contact pad and a second contact having a greater line width than the first contact; a first spacer structure interposed between the first contact and each of the bit line structures; and a second spacer structure interposed between the second contact and each of the bit line structures and having a smaller dielectric constant than the first spacer structure.

Abstract: The present disclosure provides a compound having a specific chemical structure or a pharmaceutically acceptable salt thereof having activity of degrading androgen receptor (AR). The present disclosure also provides a composition comprising such a compound or a pharmaceutically acceptable salt thereof. The present disclosure also provides a medical use of a compound according to the present disclosure, a salt thereof, and a composition comprising the same for the treatment or prophylaxis of AR-related diseases. The present disclosure also provides a method for treating or preventing an AR-related disease comprising administering to a subject in need thereof an effective amount of a compound according to the present disclosure, a salt thereof, or a composition comprising the same.

Abstract: A display device includes: a base substrate including an opening area, an opening peripheral area, and a display area at least partially surrounding the opening peripheral area, wherein the opening peripheral area is a non-display area at least partially surrounding the opening area; a thin film transistor disposed on the base substrate in the display area; a via insulating layer disposed on the thin film transistor and having a first opening surrounding the opening area, wherein the first opening is in the opening peripheral area; a pixel defining layer disposed on the via insulating layer and having a first opening which overlaps the first opening of the via insulating layer; a transparent filler disposed on the base substrate in the opening area; and a sealing substrate disposed on the transparent filler.

Abstract: A display apparatus including a display panel, a light source configured to emit light, and a light guide disposed on the light source and covering a side of the light source, the light source including a substrate, a light emitter including a light emitting stacked layer and disposed on the substrate, a light blocking layer disposed on a side surface of the light emitting stacked layer, and a reflector disposed between the substrate and the light guide, in which the light emitter has a first length direction and a second length direction, wherein orientation angles of the light emitter in the first and second length directions are different from each other, the substrate includes a first pad electrode and second pad electrode electrically connected to the light emitter, and the first and second pad electrodes are spaced apart from each other by at least 50 µm.

Abstract: A display apparatus including a display panel, a light source unit configured to provide light to the display panel, and a light guide member disposed between the display panel and the light source unit and covering the light source unit such that the light source unit is buried in the light guide member, the light guide member having a surface roughness on an upper surface thereof to diffuse light and including a substrate, and a light emitting device disposed on the substrate and including a blocking pattern to have an intensity of light emitted in an upward direction to be equal to or less than about 80% of a maximum light intensity of the light emitting device.

Abstract: Provided are a biomarker for diagnosing of the level of senescence, a composition and kit for diagnosing of the level of senescence to detect the biomarker, and a method of diagnosing the same. According to the composition and kit for the diagnosis of the level of senescence and the method of diagnosing senescence, the level of senescence of a subject is easily diagnosed, the health conditions of the subject are monitored, and a senescence-associated disease is prevented or diagnosed.

Abstract: A light emitting module unit includes a circuit board and a light emitting device. The light emitting device includes a plurality of light emitting elements electrically coupled through the circuit board, one or more electrodes arranged on a first surface of the plurality of light emitting elements, a surface barrier formed on a second surface of one or more of the plurality of light emitting elements, and an encapsulation portion disposed above a third surface of the plurality of light emitting elements. The surface barrier is disposed between the encapsulation portion and the second surface of one or more of the plurality of light emitting elements.

Abstract: The present invention relates to an artificially engineered CRISPR/Cas9 system. More particularly, the present invention relates to an artificially engineered CRISPR enzyme having enhanced target specificity and a use of an artificially engineered CRISPR/Cas9 system including the same enzyme in genome and/or epigenome manipulation or modification, genome targeting, genome editing, and in vitro diagnosis, etc.

Abstract: A light emitting diode package includes an upper housing and a lower housing. The upper housing includes a first light emitting diode (LED) chip arranged therein, a second LED chip arranged to be spaced apart from the first LED chip in a first direction, two light discharge structures, first electrodes formed on a lower surface of the first LED chip, and second electrodes formed on a lower surface of the second LED chip. The lower housing includes at least three grooves at a lower surface thereof. The lower housing further includes three or more pads. The first pair of via-holes are arranged to connect the first electrodes to one or more of the pads in a second direction perpendicular to the first direction. The second pair of via-holes are arranged to connect the second electrodes to one or more of the pads in the second direction.

Abstract: Provided are search methods and apparatuses capable of defining a search result screen in a simple and easy way. According to an aspect of the present disclosure, there is provided a search method performed by a computing device. The search method comprises receiving a search term and automatically displaying a first graphic user interface (GUI) object configured to receive a search result screen configuration scheme in response to a first user input for the received search term without an additional user input after the first user input. The first unit input is a user input other than a user input editing the search term.

Abstract: Disclosed is a training system performing training on a plurality of neural network models in parallel. The training system includes a first job proxy that receives a training request for a first neural network model and partitions a first training job corresponding to the first neural network model into first microservices, a second job proxy that receives a training request for a second neural network model and partitions a second training job corresponding to the second neural network model into second microservices, a scheduler that dynamically schedules the first microservices and the second microservices so as to be executed by heterogeneous processing units, a cluster that includes the heterogeneous processing units, sequentially executes the first microservices and sequentially executes the second microservices, and a distributed in-memory database that stores parameters generated in response to the execution of the first microservices and the second micro services.

Abstract: A display apparatus including a display panel, a light source unit configured to provide light to the display panel, and a light guide member disposed between the display panel and the light source unit and covering the light source unit such that the light source unit is buried in the light guide member, the light guide member having a surface roughness on an upper surface thereof to diffuse light and including a substrate, and a light emitting device disposed on the substrate and including a blocking pattern to have an intensity of light emitted in an upward direction to be equal to or less than about 80% of a maximum light intensity of the light emitting device.