Patents by Inventor Ri Jin KANG

Ri Jin KANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition comprising ibrutinib as effective ingredient for preventing or treating degenerative brain disease
    Patent number: 11826368
    Abstract: The present disclosure relates to a pharmaceutical composition comprising ibrutinib as an effective ingredient for preventing or treating neurodegenerative brain disease. Ibrutinib according to the present disclosure inhibits LPS-induced proinflammatory cytokine levels and BV2 microglial cell migration. In addition, ibrutinib treatment significantly reduced LPS-mediated microglial and astroglial activation. Ibrutinib treatment significantly diminished AP plaque numbers, tau hyperphosphorylation, and tau kinase CDK5 phosphorylation. Moreover, ibrutinib treatment enhances memory and thus can be used as a therapeutic agent for prevention or treatment of neurodegenerative brain disease.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 28, 2023
    Assignee: DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyang Sook Hoe, Jeoung Yeon Kim, Hye Yeon Nam, Ju Young Lee, Young Pyo Nam, Ri Jin Kang, Hyun Ju Lee
  • PHARMACEUTICAL COMPOSITION COMPRISING IBRUTINIB AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING DEGENERATIVE BRAIN DISEASE
    Publication number: 20210322419
    Abstract: The present invention relates to a pharmaceutical composition comprising ibrutinib as an effective ingredient for preventing or treating degenerative brain disease.
    Type: Application
    Filed: April 26, 2019
    Publication date: October 21, 2021
    Inventors: Hyang Sook HOE, Jeoung Yeon KIM, Hye Yeon NAM, Ju Young LEE, Young Pyo NAM, Ri Jin KANG, Hyun Ju LEE