Abstract: An implantable endoluminal prosthesis is described for use in the treatment of aneurysm involving branches. The prosthesis has a multilayer configuration, including a self-expandable braided framework extending along an axis and able to expand from a radially compressed state in a delivery configuration to a radially expanded state. The self-expandable braided framework is formed by wires, is devoid of any impermeable cover layer, includes a plurality of layers of wires made of biocompatible material, and forms a wall of the endoluminal prosthesis. Each layer forms a mesh, the meshes forming a lattice and being interlocked, the wires being integrated in the mesh of at least one of the adjacent layers. The self-expandable braided framework has a cylindrical lumen. The ratio of the surface coverage ratio of the outer layer to the surface coverage ratio of the inner layer is at least 1.5.

Abstract: The illumination optic is a collimator lens having a solid monolithic structure that includes spaced-apart and longitudinally-extending side lobed segments laterally disposed around a central core section. Each lobed segment has a TIR inner peripheral surface extending from a rear side towards a front side of the collimator lens and has a light exit surface generally facing the front side. Also disclosed is an illumination device including the collimator lens and a diffusion lens that is coaxially positioned next to its front side to redirect light coming out of the light exit surfaces. The diffusion lens has spaced-apart outlying optical regions disposed around a central optical axis, at least one for each light exit surface, to be selectively positioned in or out of alignment with a corresponding one of the light exit surfaces depending on a relative angular position between the collimator lens and the diffusion lens.

Abstract: A lens for a light-emitting diode (LED) provides an even light pattern over a desired throw of light. An indentation on the top of the lens and a lens collector on the bottom are configured for a desired spread angle of light refracted an LED positioned on a circuit board below the light collector of the lens. One or more lenses may be formed in a lens unit for assembly with a circuit boards and molding into an LED module. The module may be used in sign cabinet and other lighting applications where LEDs are used as light sources.

Abstract: A lens for a light-emitting diode (LED) provides an even light pattern over a desired throw of light. An indentation on the top of the lens and a lens collector on the bottom are configured for a desired spread angle of light refracted an LED positioned on a circuit board below the light collector of the lens. One or more lenses may be formed in a lens unit for assembly with a circuit boards and molding into an LED module. The module may be used in sign cabinet and other lighting applications where LEDs are used as light sources.

Abstract: A medical device for the delivery of treatment fluid to body vessels is described. The device has a distal (21) and a proximal (20) end with a self-expanding, hollow tubular member (9) and a delivery catheter (10) suitable for deploying a self-expanding, tubular member (9). The tubular member (9) is configured to expand radially to form a central part (11) flanked by two annular ridges, which creates, in situ, an annular lumen that can apply treatment fluid locally to a vessel and a passageway that can maintain the flow of blood through the vessel. The device is particularly suited for minimally invasive and repeatable organ perfusion. A method for organ perfusion is also disclosed.

Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Apparatus and methods are also provided for use at a vessel branching. The present invention further involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.

Abstract: An optical system having a solid state light source, such as an LED of any spectrum, includes a lens that provides an output illumination pattern of uniform distribution over a remote and larger target. The lens does not have an axis of revolution. The lens has a generally non-circular outer shape in cross section and on top views, where the outer optical surfaces are angled one relative to another. The lens includes refractive and reflective active optical surfaces to split, direct and shape the incoming beam from the light source towards the target in the form of several angled beams of prescribed energies calculated as a function of the shape of the target and distance to the target. The lens has an inner primary and partially open optical cavity of a polygonal cross section facing the light source.

Abstract: The present invention involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.

Abstract: The present invention involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.

Abstract: An optical system having a solid state light source, such as an LED of any spectrum, includes a lens that provides an output illumination pattern of uniform distribution over a remote and larger target. The lens does not have an axis of revolution. The lens has a generally non-circular outer shape in cross section and on top views, where the outer optical surfaces are angled one relative to another. The lens includes refractive and reflective active optical surfaces to split, direct and shape the incoming beam from the light source towards the target in the form of several angled beams of prescribed energies calculated as a function of the shape of the target and distance to the target. The lens has an inner primary and partially open optical cavity of a polygonal cross section facing the light source.

Abstract: A medical device for the delivery of treatment fluid to body vessels is described. The device has a distal (21) and a proximal (20) end with a self-expanding, hollow tubular member (9) and a delivery catheter (10) suitable for deploying a self-expanding, tubular member (9). The tubular member (9) is configured to expand radially to form a central part (11) flanked by two annular ridges, which creates, in situ, an annular lumen that can apply treatment fluid locally to a vessel and a passageway that can maintain the flow of blood through the vessel. The device is particularly suited for minimally invasive and repeatable organ perfusion. A method for organ perfusion is also disclosed.

Abstract: The present invention involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.