Patents by Inventor Éric Rhéaume

Éric Rhéaume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Co-culture system and method for in vitro assessment of reverse cholesterol transport
    Patent number: 11840707
    Abstract: The present invention provides a co-culture system and method for assessing cellular cholesterol (Choi) efflux and uptake in vitro. The co-culture system mimics in vivo Choi efflux and uptake in the context of mammalian physiology. The methods and systems provided can be used in some embodiments to evaluate the effect of a pharmacological agent on cellular Choi efflux and uptake or for diagnostic purposes.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: December 12, 2023
    Assignee: INSTITUT DE CARDIOLOGIE DE MONTREAL
    Inventors: David Rhainds, Éric Rhéaume, David Busseuil, Jean-Claude Tardif
  • METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS
    Publication number: 20210290623
    Abstract: The invention provides compositions and methods useful for treating or preventing cardiovascular disorders and lowering risk of cardiovascular events.
    Type: Application
    Filed: June 1, 2021
    Publication date: September 23, 2021
    Inventors: Marie-Pierre DUBÉ, Jean-Claude TARDIF, Eric RHÉAUME
  • METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS
    Publication number: 20200222406
    Abstract: The invention provides compositions and methods useful for treating or preventing cardiovascular disorders and lowering risk of cardiovascular events.
    Type: Application
    Filed: January 13, 2020
    Publication date: July 16, 2020
    Inventors: Marie-Pierre DUBÉ, Jean-Claude TARDIF, Eric RHÉAUME
  • A CO-CULTURE SYSTEM AND METHOD FOR IN VITRO ASSESSMENT OF REVERSE CHOLESTEROL TRANSPORT
    Publication number: 20190284527
    Abstract: The present invention provides a co-culture system and method for assessing cellular cholesterol (Choi) efflux and uptake in vitro. The co-culture system mimics in vivo Choi efflux and uptake in the context of mammalian physiology. The methods and systems provided can be used in some embodiments to evaluate the effect of a pharmacological agent on cellular Choi efflux and uptake or for diagnostic purposes.
    Type: Application
    Filed: May 30, 2017
    Publication date: September 19, 2019
    Inventors: David RHAINDS, Éric RHÉAUME, David BUSSEUIL, Jean-Claude TARDIF
  • METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS
    Publication number: 20190070178
    Abstract: The invention provides compositions and methods useful for treating or preventing cardiovascular disorders and lowering risk of cardiovascular events.
    Type: Application
    Filed: August 28, 2018
    Publication date: March 7, 2019
    Inventors: Marie-Pierre DUBÉ, Jean-Claude TARDIF, Eric RHÉAUME
  • PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION COMPRISING AN APOLIPOPROTEIN PEPTIDE/PHOSPHOLIPID COMPLEX
    Publication number: 20150374675
    Abstract: The present invention features pharmaceutical compositions and methods of using pharmaceutical compositions for treating left ventricular diastolic dysfunction. In particular, the pharmaceutical compositions include an apolipoprotein complex comprising a lipid fraction and a protein fraction.
    Type: Application
    Filed: September 14, 2015
    Publication date: December 31, 2015
    Inventors: Jean-Claude TARDIF, David BUSSEUIL, Eric RHÉAUME
  • PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION COMPRISING AN APOLIPOPROTEIN PEPTIDE/PHOSPHOLIPID COMPLEX
    Publication number: 20140309426
    Abstract: The present invention features pharmaceutical compositions and methods of using pharmaceutical compositions for treating left ventricular diastolic dysfunction. In particular, the pharmaceutical compositions include an apolipoprotein complex comprising a lipid fraction and a protein fraction.
    Type: Application
    Filed: June 23, 2014
    Publication date: October 16, 2014
    Inventors: Jean-Claude TARDIF, David Busseuil, Eric Rhéaume
  • PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION COMPRISING AN APOLIPOPROTEIN PEPTIDE/PHOSPHOLIPID COMPLEX
    Publication number: 20130197226
    Abstract: The present invention features pharmaceutical compositions and methods of using the pharmaceutical compositions for treating left ventricular diastolic dysfunction. In particular, the pharmaceutical compositions include an apolipoprotein complex comprising a lipid fraction and a protein fraction.
    Type: Application
    Filed: July 19, 2011
    Publication date: August 1, 2013
    Inventors: Jean-Claude Tardif, David Busseuil, Éric Rhéaume
  • PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION
    Publication number: 20120021982
    Abstract: The present invention features pharmaceutical compositions and methods of using the pharmaceutical compositions for treating left ventricular diastolic dysfunction. In particular, the pharmaceutical compositions include an apolipoprotein complex comprising a lipid fraction and a protein fraction.
    Type: Application
    Filed: July 19, 2011
    Publication date: January 26, 2012
    Inventors: Jean-Claude Tardif, David Busseuil, Eric Rheaume
  • Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction
    Publication number: 20110288072
    Abstract: Use of ivabradine, or 3-{3-[{[(7S)-3,4-dimethoxybicyclo [4.2.0]octa-1,3,5-trien-7-yl]-methyl }-(methyl)-amino]-propyl}-7,8-dimethoxy-1,3,4,5 -tetrahydro-2H-3-benzazepin-2-one, its addition salts with a pharmaceutically acceptable acid and their hydrates, for obtaining a medicament intended for the treatment of endothelial dysfunction.
    Type: Application
    Filed: July 21, 2011
    Publication date: November 24, 2011
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Vidal Benatar, Guy Lerebours-Pigeonniere, Jean-Claude Tardif, Eric Thorin, Eric Rheaume
  • Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction
    Publication number: 20080200450
    Abstract: Use of ivabradine, or 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-methyl}-(methyl)-amino]-propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one, its addition salts with a pharmaceutically acceptable acid and their hydrates, for obtaining a medicament intended for the treatment of endothelial dysfunction.
    Type: Application
    Filed: January 11, 2008
    Publication date: August 21, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Vidal Benatar, Guy Lerebours-Pigeonniere, Jean-Claude Tardif, Eric Thorin, Eric Rheaume