Patents by Inventor Ricardo Filipe Antunes Pinheiro

Ricardo Filipe Antunes Pinheiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening method for compounds that reduce ER stress
    Patent number: 8236490
    Abstract: The present invention relates to a cell comprising an Endoplasmic Reticulum (ER) stress element operably linked to a reporter element and an exogenous gene encoding a protein that induces ER stress. Methods of screening using the modified cell, constructs used in the modified cell, the candidate agents identified by the screen and uses thereof are also part of the invention.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: August 7, 2012
    Assignee: EM Biotecnologia S.A.
    Inventors: Christophe Francois Aime Roca, José Manuel Bernardo Sousa, Marta Isabel Heitor Cerejo, Alexandra Maria Barros Dos Santos, Cátia Santana Reverendo Rodrigues, Ricardo Filipe Antunes Pinheiro, Patricia Ramalhete Mendes da Silva Calado, Sukalyan Chatterjee, Helena Margarida Moreira de Oliveira Vieira
  • USE OF COMPOUNDS IN THE TREATMENT OF TAU-INDUCED CYTOTOXICITIES
    Publication number: 20110294741
    Abstract: The present invention relates to derivatives of L-Tyrosyl-L-Arginine and the use of said derivatives in the prevention and/or treatment of a tau-induced cytotoxicity.
    Type: Application
    Filed: April 1, 2009
    Publication date: December 1, 2011
    Applicant: Bioalvo-Servicos, Investigacao e Desenvolvimento em Biotecnologia S.A.
    Inventors: Alexandra Maria Barros Dos Santos, Catia Santana Reverendo Rodrigues, Christophe Francois Aime Roca, Helena Margarida Moreira de Oliveira Vieira, Jose Manuel Bernardo de Sousa, Marta Isabel Heitor Cerejo, Patricia Ramalhete Mendes da Silva Calado, Ricardo Filipe Antunes Pinheiro, Sukalyan Chatterjee, Marta Maria Batista Ribeiro, Miguel Augusto Rico Botas Castanho, Eduard Bardaji Rodriguez, Montserrat Heras Corominas, Isaura Ferreira Tavares, Marta Sofia Carvalho Teixeira Pinto
  • SCREENING METHOD FOR COMPOUNDS THAT REDUCE ER STRESS
    Publication number: 20100215641
    Abstract: The present invention relates to a cell comprising an Endoplasmic Reticulum (ER) stress element operably linked to a reporter element and an exogenous gene encoding a protein that induces ER stress. Methods of screening using the modified cell, constructs used in the modified cell, the candidate agents identified by the screen and uses thereof are also part of the invention.
    Type: Application
    Filed: June 6, 2008
    Publication date: August 26, 2010
    Applicant: Bioalvo-Servicos, Investigacao e Desenvolvirmento em Biotecnologis S.A.
    Inventors: Christophe Francois Aime Roca, Jose Manuel Bernardo Sousa, Marta Isabel Heitor Cerejo, Alexandra Maria Barros Dos Santos, Catia Santana Reverendo Rodrigues, Ricardo Filipe Antunes Pinheiro, Patricia Ramalhete Mendes da Silva Calado, Sukalyan Chatterjee, Helena Margarida Moreira de Oliveira Vieira
  • YEAST PLATFORM CONSTRUCTION AND SCREENING METHODS
    Publication number: 20100081699
    Abstract: The present invention relates to a cell which is suitable for screening a candidate agent as being an inhibitor of the metabolism of tryptophan to NAD+ and/or a modulator of NAD+ levels, which cell comprises functional genes of a pathway enabling the metabolism of tryptophan to NAD+ and wherein the cell includes a copy of an exogenous gene of said pathway, from the same or different species as the cell, which exogenous gene is under the control of an inducible or constitutive promoter and wherein any endogenous copy of the gene having the same function as the exogenous gene is a non functioning gene. The present invention also relates to populations of such cells and to methods of screening candidate agents with such cells.
    Type: Application
    Filed: December 19, 2007
    Publication date: April 1, 2010
    Applicant: Bioalvo-Servicos ,Investigacao e Desenvolvimento em Biotlecnologia S.A.
    Inventors: Christophe Francois Aimé Roca, José Manuel Bernardo Sousa, Marta Isabel Heitor Cerejo, Alexandra Maria Barros Dos Santos, Cátia Santana Reverendo Rodrigues, Ricardo Filipe Antunes Pinheiro, Johannes Sam, Patricia Ramalhete Mendes da Silva Calado, Sukalyan Chatterjee, Helena Margarida Moreira de Oliveira Vieira