Abstract: A computer-implemented method, computer program product and prototyping platform creates a design blueprint for a substrate-based microfluidic device. A design and prototyping platform receives at least one blueprint parameter and at least one constraint associated with a proposed substrate-based microfluidic device including a hydrophilic material and arrangement of a pattern of a hydrophobic material. The platform determines an arrangement of a plurality of microfluidic device elements as candidates for implementation of the proposed substrate-based microfluidic device and outputs a design blueprint of the proposed substrate-based microfluidic device.

Abstract: A multiplexed lateral flow assay device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir and divides a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable paper top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable paper top cover.

Abstract: A multiplexed lateral flow device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir. The fluid distributor pad includes a paper based microfluidic element having a pattern of a hydrophobic material to distribute a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays.

Abstract: A rechargeable power source in an autonomous vehicle (AV) adapted to traverse within a pipe network is charged, the charging using mechanical power derived from a flow of material within the pipe network. A sensor in the AV is powered from the charged rechargeable power source. Using power from the rechargeable power source, the AV is caused to traverse within the pipe network.

Abstract: Fabricating a fluid testing device includes receiving a substrate, and applying a pattern of hydrophobic material to the substrate. The substrate is positioned between layers of a thermally reflective material. Heat and pressure is applied to the substrate and thermally reflective material to reflow the pattern of hydrophobic material. A protective coating is applied over a portion of the substrate to form the fluid testing device.

Abstract: In response to receiving an input of a user criteria for operating a system, one or more predictive models are selected in dependence on the user criteria. The predictive models predict behavior of the system and are stored in the memory with one or more system performance models that control operation of the system. The selected performance model(s) is implemented to select a subset of sensors that monitor physical conditions of the system and/or environmental parameters thereof, and is also used to select one or more of the system performance models that conform to the user criteria. One or more actuators associated with the system are controlled according to inputs received from the selected subset of sensors and the selected performance model(s). The same concepts are valid for other areas rather than maintenance, like optimization in the area of the internet of things, dynamic system reconfiguration, preventive healthcare.

Abstract: A computer-implemented method for medical procedure assessment and evaluation is provided. The method receives, by a processor, a claim record and stores the claim record as a claim. The method classifies, by the processor, the claim using an intelligent system including an inference engine and knowledge base and classifies, by the processor, a probability of a diagnostic using the intelligent system. The method calculates, by the processor, using the probability of the diagnostic and the claim a probability of consistency of the diagnostic using the intelligent system and presents, by the processor, the probability of consistency of the diagnostic to a user.

Abstract: A method for image capture for colorimetric analysis includes inserting a colorimetric sample into a slot formed in a base of a device. The device includes a lid surrounding and covering the base. The lid includes a central opening, and a plurality of lights are within the lid and surrounding the opening. The method also includes selecting one or more wavelengths and intensities for illuminating the sample within the device, illuminating the sample within the device with the selected one or more wavelengths and intensities by selectively activating one or more of the plurality of lights, adjusting a height of a camera over the sample to focus the sample in the camera, and capturing at least one image of the sample using the camera.

Abstract: A target sample to be chemically analyzed is received at a microfluidic device which is part of an analysis card. The microfluidic device includes at least one input layer configured to receive the target sample, at least one intermediary layer, and at least one readout layer configured to present one or more color attributes at one or more readout regions in response to one or more colorimetric reactions to the target sample. An image of the readout layer of the microfluidic device is obtained. A calibration file that corresponds to the analysis card is obtained. The calibration file includes a calibrated model of at least one color attribute based on data from at least one known chemical attribute of at least one standard sample processed by a calibration card.

Abstract: A method for image capture for colorimetric analysis includes inserting a colorimetric sample into a slot formed in a base of a device. The device includes a lid surrounding and covering the base. The lid includes a central opening, and a plurality of lights are within the lid and surrounding the opening. The method also includes selecting one or more wavelengths and intensities for illuminating the sample within the device, illuminating the sample within the device with the selected one or more wavelengths and intensities by selectively activating one or more of the plurality of lights, adjusting a height of a camera over the sample to focus the sample in the camera, and capturing at least one image of the sample using the camera.

Abstract: A microfluidic device, including a controllable shape-changing micropillar where a shape of the shape-changing micropillar is changed by a fluid.

Abstract: A microfluidic device, including a matrix array of controllable shape-changing micropillars where a shape of the shape-changing micropillars is changed by a fluid.

Abstract: A microfluidic device, including a matrix array of controllable shape-changing micropillars where a shape of the shape-changing micropillars is changed by a fluid.

Abstract: A microfluidic device, including a substrate including a microchannel, an activation setup disposed in the microchannel, and a matrix array of controllable shape-changing micropillars connected to the activation setup. A shape of the controllable shape-changing micropillars changes based on an activation of the activation setup.

Abstract: A microfluidic device, including a substrate including a microchannel, an activation setup disposed in the microchannel, and a matrix array of controllable shape-changing micropillars connected to the activation setup. A shape of the controllable shape-changing micropillars changes based on an activation of the activation setup.

Abstract: Sensor data is detected from at least one sensor selected and installed for detecting operating conditions of at least one equipment. The sensor data includes an operating condition of at least one equipment. The sensor is selected dependent on indications of a user restriction and a predictive model. A sensor data signal is generated dependent on the sensor data. The sensor data signal is transmitted to a network device for collecting the sensor data and transforming the collected sensor data into a formatted transmission signal having a format for transmission over a network to a network server. The network server receives the formatted transmission signal for performing on-demand service of at least one of analysis, reporting and visualization dependent on the operating condition.

Abstract: In response to receiving an input of a user criteria for operating a system, one or more predictive models are selected in dependence on the user criteria. The predictive models predict behavior of the system and are stored in the memory with one or more system performance models that control operation of the system. The selected o model(s) is implemented to select a subset of sensors that monitor physical conditions of the system and/or environmental parameters thereof, and is also used to select one or more of the system performance models that conform to the user criteria. One or more actuators associated with the system are controlled according to inputs received from the selected subset of sensors and the selected performance model(s). The same concepts are valid for other areas rather than maintenance, like optimization in the area of the internet of things, dynamic system reconfiguration, preventive healthcare.

Abstract: A system for manipulating electric fields within a microscopic fluid channel includes a fluid channel with an inlet and an outlet to support fluid flow, at least one controllable electric field producer that applies a non-uniform and adjustable electric field to one or more regions of the fluid channel, one or more sensors that measure one or more parameters of a fluid flowing through the fluid channel, and a controller with hardware and software components that receives signals from the one or more sensors representative of values of the one or more parameters and, based on the parameter values, drives one or more actuators to adjust the electric field produced by the plurality of electric field producers.