Abstract: A device for the quantification of cellular and non-cellular components in a blood sample including detection electrodes including a first electrode connected with a first input to receive a first signal in input and a second electrode, reference electrodes including a first electrode connected with a second input configured to receive a second signal in input of opposite polarity to the first input signal and a second electrode connected to the second electrode of said detection electrodes, in a common point wherefrom an output signal is picked up, a ferromagnetic concentrator that cooperates with an external magnetic field external to effectuate concentration of said components on said detection electrodes, a substrate configured to house said detection electrodes, reference electrodes, and concentrator; a support configured to collect a blood sample, and a spacer element to confine in the substrate plane the blood sample and to distance said substrate from said support.

Abstract: A device for sensing a magnetic field, comprising a closed superconducting loop configured to collect a magnetic field to be sensed, hereinafter external magnetic field, the closed superconducting loop having a path width (wp) and being provided with a constriction having a width (wc) narrower than the path width, the constriction generating a non-uniform magnetic field, hereinafter internal magnetic field, in response to the external magnetic field, a vibrating mechanical oscillator coupled to, or formed by the constriction and responsive to the internal magnetic field, and a detector configured to detect deflection or vibration of the mechanical oscillator and providing a signal indicative of the deflection or vibration.

Abstract: An opto-magnetic device includes an integrated optical circuit having an input for an input optical radiation and at least one output for an output optical radiation. The optical circuit defines an area sensible to the variations of a local refraction index probed by the optical radiation, destined to come in contact with the sample. A plurality of probe molecules are included to anchor to the sensible area, and a plurality of magnetic particles are included to anchor to molecules of the analyte, bound to the probe molecules upon a molecular recognition. A magnetic actuator is configured to generate a variable magnetic field and oscillate the magnetic particles to cause variation of the refraction index probed by the optical radiation in the sensible area, and a variation of at least one characteristic parameter of the output optical radiation correlated to a concentration of the molecules of the analyte.

Abstract: Apparatus (100) for the quantification of biological components (3, 3?, 3?) in a fluid comprising: a measurement cell (1) comprising detection electrodes (4, 4?, 5, 5?, 6, 6?, 34, 34?, 84, 84?, 94, 94?, 184, 184?, 194, 194?) and reference electrodes (7, 7,? 8, 8?, 9, 9?, 37, 37?, 64, 64?, 74, 74?, 164, 164?, 174?); an electronic unit (201) for the generation of input signals, impedimetric measurement, amplification of output signals and communication with a user interface; means for the generation of a magnetic field (101, 102, 103) with an appropriate gradient that can be modulated in time, said means of magnetisation being configured to generate a magnetic field capable of causing, in combination with concentrators (10, 10?, 10?, 14, 14?, 14?, 15) housed in the measurement cell, the separation of the components (3, 3?, 3?) to be quantified from the rest of the solution and their concentration on the detection electrodes (4, 4?, 5, 5?, 6, 6?, 34, 34?, 84, 84?, 94, 94?, 184, 184?, 194, 194?).

Abstract: A device for sensing a magnetic field, comprising a closed superconducting loop configured to collect a magnetic field to be sensed, hereinafter external magnetic field, the closed superconducting loop having a path width (wp) and being provided with a constriction having a width (wc) narrower than the path width, the constriction generating a non-uniform magnetic field, hereinafter internal magnetic field, in response to the external magnetic field, a vibrating mechanical oscillator coupled to, or formed by the constriction and responsive to the internal magnetic field, and a detector configured to detect deflection or vibration of the mechanical oscillator and providing a signal indicative of the deflection or vibration.

Abstract: A device for the quantification of cellular and non-cellular components in a blood sample including detection electrodes including a first electrode connected with a first input to receive a first signal in input and a second electrode, reference electrodes including a first electrode connected with a second input configured to receive a second signal in input of opposite polarity to the first input signal and a second electrode connected to the second electrode of said detection electrodes, in a common point wherefrom an output signal is picked up, a ferromagnetic concentrator that cooperates with an external magnetic field external to effectuate concentration of said components on said detection electrodes, a substrate configured to house said detection electrodes, reference electrodes, and concentrator; a support configured to collect a blood sample, and a spacer element to confine in the substrate plane the blood sample and to distance said substrate from said support.

Abstract: An opto-magnetic device includes an integrated optical circuit having an input for an input optical radiation and at least one output for an output optical radiation. The optical circuit defines an area sensible to the variations of a local refraction index probed by the optical radiation, destined to come in contact with the sample. A plurality of probe molecules are included to anchor to the sensible area, and a plurality of magnetic particles are included to anchor to molecules of the analyte, bound to the probe molecules upon a molecular recognition. A magnetic actuator is configured to generate a variable magnetic field and oscillate the magnetic particles to cause variation of the refraction index probed by the optical radiation in the sensible area, and a variation of at least one characteristic parameter of the output optical radiation correlated to a concentration of the molecules of the analyte.

Abstract: Method for magnetic nanopatterning of a substrate 10, said substrate comprising a first ferromagnetic or ferrimagnetic phase FM and a second antiferromagnetic phase AF, said FM and AF phases being coupled by exchange bias in such a way to form an exchange bias system; said method comprising submitting said substrate to a magnetic field Hw so as to set the magnetization of said first phase FM in the direction of said magnetic field Hw, while heating predefined portions of said antiferromagnetic phase AF up to a writing temperature TW at which the exchange bias can be influenced, equipment for carrying out said method and substrate nanopatterned according to said method.

Abstract: A sensor is described for detecting the presence of a magnetic nanoparticle (N). The sensor is arranged on a support (1), on which a plurality of non-magnetic contacts (Iin, GND, V1, V2) electrically conductively connected to the sensor is disposed. The contacts are adapted to be connected to means for measuring magnetoresistance. The sensor includes a planar ferromagnetic nanostructure (3), comprising a detection area (31) shaped as a strip bent to form a corner. The detection area is adapted to selectively assume, as a response to an applied magnetic field, a first spin configuration comprising a transverse “head-to-head” domain wall (TW), and a second spin configuration, wherein such domain wall (TW) is absent. The transition from the first configuration to the second configuration is affected by the proximity of a magnetic nanoparticle (N) to the detection area.

Abstract: A sensor is described for detecting the presence of a magnetic nanoparticle (N). The sensor is arranged on a support (1), on which a plurality of non-magnetic contacts (Iin, GND, V1, V2) electrically conductively connected to the sensor is disposed. The contacts are adapted to be connected to means for measuring magnetoresistance. The sensor includes a planar ferromagnetic nanostructure (3), comprising a detection area (31) shaped as a strip bent to form a corner. The detection area is adapted to selectively assume, as a response to an applied magnetic field, a first spin configuration comprising a transverse “head-to-head” domain wall (TW), and a second spin configuration, wherein such domain wall (TW) is absent. The transition from the first configuration to the second configuration is affected by the proximity of a magnetic nanoparticle (N) to the detection area.