Patents by Inventor Riccardo Ghidoni

Riccardo Ghidoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating cardiac reperfusion injury
    Patent number: 9925160
    Abstract: The inventors have made the surprising discovery that when ceramide production is upregulated in the infarct and at-risk areas upon reperfusion injury in the heart, such upregulation is effected through the de novo ceramide synthesis pathway. Upon treatment of cardiac tissues subject to reperfusion injury with a specific inhibitor of the novo ceramide synthesis pathway (myriocin), the inventors have determined that the inhibition of such pathway not only reduces the inflammation of the interested area, but most surprisingly reduces infarct size, ameliorates cardiac contractility and activates cell detoxification and survival programs. There is thus provided an inhibitor of de novo ceramide synthesis pathway, particularly myriocin, for the treatment of cardiac reperfusion injury.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: March 27, 2018
    Assignees: UNIVERSITA' DEGLI STUDI DI MILANO, POLICLINICO SAN DONATO S.P.A.
    Inventors: Riccardo Ghidoni, Paola Signorelli, Luigi Anastasia
  • Use of serine palmitoyl transferase inhibitors for preventing and delaying inherited retinal degenerations and compositions thereof
    Patent number: 9114119
    Abstract: The method for preventing and delaying inherited retinal degenerations using serine palmitoyltransferase inhibitors, and compositions which contain them.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: August 25, 2015
    Assignees: Universita' degli Studi di Milano, Consiglio Nazionale delle Ricerche, Universita' degli Studi de Pisa, Nanovactor S.R.L.
    Inventors: Riccardo Ghidoni, Enrica Strettoi, Maria Claudia Gargini, Paolo Gasco
  • SERINE PALMITOYLTRANSFERASE INHIBITORS FOR PREVENTING AND DELAYING RETINITIS PIGMENTOSA
    Publication number: 20120040007
    Abstract: The method for preventing and delaying inherited retinal degenerations using serine palmitoyltransferase inhibitors, and compositions which contain them.
    Type: Application
    Filed: February 23, 2010
    Publication date: February 16, 2012
    Applicants: UNIVERSITA' DEGLI STUDI DI MILANO, NANOVECTOR S.R.L., UNIVERSITA' DEGLI STUDI DL PISA, CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Riccardo Ghidoni, Enrica Strettoi, Maria Claudia Gargini, Paolo Gasco