Patents by Inventor Riccardo SABATINI

Riccardo SABATINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS MODULATING PROTEIN RECRUITMENT AND/OR DEGRADATION
    Publication number: 20230111853
    Abstract: The invention provides cereblon binders for the degradation of proteins by the ubiquitin proteasome pathway for therapeutic applications.
    Type: Application
    Filed: December 16, 2020
    Publication date: April 13, 2023
    Inventors: Nikolai KLEY, Riccardo SABATINI, Edward SUH
  • BIFUNCTIONAL AGENTS FOR PROTEIN RECRUITMENT AND/OR DEGRADATION
    Publication number: 20230099031
    Abstract: The disclosure relates to new compounds, including bifunctional compounds, to be used as modulators of ubiquitination for targeted protein degradation.
    Type: Application
    Filed: December 16, 2020
    Publication date: March 30, 2023
    Inventors: Nikolai KLEY, Riccardo SABATINI, Edward SUH
  • MODULATION OF PROTEIN DEGRADATION
    Publication number: 20230020607
    Abstract: Methods of assessing the efficacy of an agent in treating a disease or disorder are provided that include determining whether the agent causes, or inhibits, direct or indirect recruitment and/or ubiquitination and/or degradation of argininosuccinate synthetase 1 (ASS1).
    Type: Application
    Filed: December 15, 2020
    Publication date: January 19, 2023
    Inventors: Nikolai KLEY, Samuel LIEVENS, Riccardo SABATINI
  • PARTICLE BASED SMALL MOLECULE-PROTEIN COMPLEX TRAP
    Publication number: 20220026439
    Abstract: The present invention relates to the use of a particle, including a virus-like particle (VLP), for the discovery and analysis of protein-protein interactions that are modulated by small molecules.
    Type: Application
    Filed: December 19, 2019
    Publication date: January 27, 2022
    Inventors: Nikolai KLEY, Samuel LIEVENS, Riccardo SABATINI
  • IDENTIFICATION OF INDIVIDUALS BY TRAIT PREDICTION FROM THE GENOME
    Publication number: 20190259473
    Abstract: Described are methods and systems for identifying phenotypic traits of an individual from nucleotide sequence data. The methods and systems are useful even when the identity of the individual or phenotypic traits of the individual is unknown.
    Type: Application
    Filed: August 7, 2017
    Publication date: August 22, 2019
    Inventors: Franz J. OCH, M. Cyrus MAHER, Victor LAVRENKO, Christoph LIPPERT, David HECKERMAN, David SHUTE, Okan ARIKAN, Riccardo SABATINI, Eun Young KANG, Peter GARST, Axel BERNAL, Mingfu ZHU, Alena HARLEY, Theodore WONG, Seunghak LEE