Abstract: A neural prosthetic micro system includes an electrode array coupled to an integrated circuit (IC) which may include signal conditioning and processing circuitry. The IC may include a high pass filter that passes signals representative of local field potential (LFP) activity in a subject's brain.

Abstract: In an embodiment, neural activity of a subject may be measured with an implant in the sensory motor cortex of the subject and used to predict an intended movement. The measured neural activity may be the local field potential (LFP) at an electrode or single unit (SU) activity. The spectral structure of the LFP and the SU activity may be estimated using spectral analysis techniques. The estimated LFP and SU responses may be used to predict and intended movement by the subject.

Abstract: The present invention provides a processed neural signal that encodes a reach plan, comprising the target location of the planned encoded relative to an eye-centered reference frame. The present invention also provides methods for generating and decoding the processed neural signal.

Abstract: In an embodiment, neural activity of a subject may be measured with an implant in the sensory motor cortex of the subject and used to predict an intended movement. The measured neural activity may be the local field potential (LFP) at an electrode or single unit (SU) activity. The spectral structure of the LFP and the SU activity may be estimated using spectral analysis techniques. The estimated LFP and SU responses may be used to predict and intended movement by the subject.

Abstract: The present invention provides a processed neural signal that encodes a reach plan, comprising the target location of the planned reach encoded relative to an eye-centered reference frame. The present invention also provides methods for generating and decoding the processed neural signal.

Abstract: A prosthetic system may use a decoder to predict an intended action, such as a reach, from processed signals generated from measured neural activity. The decoder may included a cognitive state machine, which transitions between cognitive states based on transition rules.

Abstract: In an embodiment, neural activity of a subject may be measured with an implant in the sensory motor cortex of the subject and used to predict an intended movement. The measured neural activity may be the local field potential (LFP) at an electrode or single unit (SU) activity. The spectral structure of the LFP and the SU activity may be estimated using spectral analysis techniques. The estimated LFP and SU responses may be used to predict and intended movement by the subject.

Abstract: A chronic chamber microdrive (“CCMD”) for neural recording. In one implementation, a CCMD for neural recording from a target site of neural tissue exposed by an opening in a skull of a subject, includes: an outer cylinder, having a longitudinal axis, positioned within the opening and rotatable within the opening; an inner cylinder positioned within the outer cylinder, such that the longitudinal axis of the outer cylinder is within a circumference of the inner cylinder and the inner cylinder rotates within the rotatable outer cylinder; at least one fine leadscrew, positioned longitudinally in the inner cylinder; at least one electrode for neural recording, where at least one of said electrodes is coupled to a corresponding one of said fine leadscrews, where said electrodes are positioned horizontally by rotating the outer cylinder and separately rotating the inner cylinder, and where said electrodes are positioned vertically by rotating said fine leadscrews.