Patents by Inventor Richard A. Clark
Richard A. Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10254246Abstract: A method is provided for measuring an electrolytically-active species concentration in an aqueous or non-aqueous solution for use in providing control of the concentration of the species in a source solution thereof based on the measurements. In the method, a sample containing an electrolytically-active species is added into a measurement cell that has a working electrode and an auxiliary electrode, and a constant current is applied to the measurement cell while the working and auxiliary electrodes are in contact with the sample with monitoring of voltage difference across the electrodes until a change in the voltage difference is detected. A feedback signal is generated based on a parameter of the change in the voltage difference that is directly proportional to the amount of the electrolytically-active species in the sample, which can be used for process control. An apparatus is also described.Type: GrantFiled: April 26, 2013Date of Patent: April 9, 2019Assignee: Buckman Laboratories International, Inc.Inventors: Thomas E. McNeel, Richard A. Clark, Richard D. Lusk, Jr., Chamindu Liyanapatirana
-
Patent number: 9630847Abstract: A method of controlling an exothermic or endothermic chemical reaction is provided. The method involves measuring a temperature of a first reactant flowing at a first flow rate, contacting the first reactant with a second reactant flowing at a second flow rate to form a reaction product, measuring the temperature of the reaction product, and determining the temperature difference between the temperature of the first reactant and the temperature of the reaction product. The method can further involve adjusting the flow rate of at least one of the first reactant and the second reactant, or shutting down flow, based on the temperature difference. An apparatus to carry out the method is also provided. The method and apparatus can be useful in controlling many different reactions, including the reaction of sodium hypochlorite and ammonia to form monochloramine.Type: GrantFiled: September 24, 2013Date of Patent: April 25, 2017Assignee: Buckman Laboratories International, Inc.Inventors: Thomas E. McNeel, Richard A. Clark, Richard D. Lusk, Jr.
-
Patent number: 9389643Abstract: A mobile computer workstation for use with a computer network is disclosed. The workstation can include a wheeled chassis having a vertical beam that supports a horizontal work surface. An input device tray is located at a front side of the work surface and a bracket located at a rear side of the work surface mounts a display screen to the workstation above and off the work surface. A power unit including a battery charger and a battery is mounted to the chassis and supplies power to the display screen.Type: GrantFiled: February 18, 2015Date of Patent: July 12, 2016Assignee: InterMetro Industries CorporationInventors: Richard A. Clark, Michael R. Jacobs, Steven B. Flemig, Fouad Geries Abu-Akel, Darin Janoschka, Keith Washington
-
Patent number: 9347928Abstract: A method and composition is described for controlling the growth of fouling materials, such as scale, in aqueous systems using a tagged (fluorescent) polymer. The tagged polymer can be a fluorescent polymer which has at least one fluorescent monomeric unit derived from a fluorophore which has at least one terminal end comprising an olefinic group. The method of controlling the growth of at least one fouling material in an aqueous system can include the steps of adding the tagged polymer to the aqueous system to be treated, fluorometrically monitoring the concentration of the tagged polymer, and adjusting, as needed, the concentration of the tagged polymer and proportionally used water treatment compound or compounds effective to control the growth of at least one fouling material. The adjustment of pH before determination of the fluorescence signal can be employed to increase sensitivity of the fluorophore and minimize background interference.Type: GrantFiled: July 30, 2012Date of Patent: May 24, 2016Assignee: Buckman Laboratories International, Inc.Inventors: Thomas E. McNeel, Marilyn S. Whittemore, Richard A. Clark, Jadwiga J. Grabowicz
-
Patent number: 9078436Abstract: The present invention provides a method of treating an aqueous system for biocide control, by adding an acidified solution that includes monoalkyldithiocarbamate salt and alkyl isothiocyanate to an aqueous system. A biocide feed system is also provided that is configured to generate a reproducible level of alkyl isothiocyanate. The method and system provide effective levels of alkyl isothiocyanate for rapid biocidal activity, along with levels of monoalkyldithiocarbamate salt which can decompose to form additional alkyl isothiocyanate and provide longer-term biocidal activity.Type: GrantFiled: September 10, 2013Date of Patent: July 14, 2015Assignee: Buckman Laboratories International, Inc.Inventors: Thomas E. McNeel, Richard A. Clark, William C. Ganus, Richard D. Lusk, Jr., Graciela H. Vunk, Luis A. Zugno
-
Publication number: 20150118726Abstract: Methods for controlling the growth of bacteria in ethanol fermentation systems with antibiotic alternatives, which can be nonoxidizing biocides, stabilized oxidizers, or any combinations thereof, are described. As an option, a process or composition of the present invention can include one or more polycyclic antibacterial peptides. The methods can provide improvements, such as increased ethanol yields with minimal carryover of biocide into co-products of the processes.Type: ApplicationFiled: December 30, 2014Publication date: April 30, 2015Applicant: BUCKMAN LABORATORIES INTERNATIONAL, INC.Inventors: Christopher L. Wiatr, Michael L. Corcoran, Thomas E. McNeel, Richard A. Clark, Rita de Cassia Bortoto Porto, David Oppong, Philip Hoekstra
-
Publication number: 20150087597Abstract: Described herein are fragments of fibronectin and vitronectin and variants thereof that have certain activities, including growth factor-binding activity. Also described are fragments of growth factors that bind to fibronectin and inhibit binding of full-length growth factors to fibronectin. Compositions containing such fragments are useful in cosmetic treatments (e.g., the treatment of wrinkles or UV photodamage of skin), and the treatment of wounds and cancer.Type: ApplicationFiled: May 1, 2014Publication date: March 26, 2015Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORKInventor: Richard A. Clark
-
Patent number: 8951960Abstract: Methods for controlling the growth of bacteria in ethanol fermentation systems with antibiotic alternatives, which can be nonoxidizing biocides, stabilized oxidizers, or any combinations thereof, are described. As an option, a process or composition of the present invention can include one or more polycyclic antibacterial peptides. The methods can provide improvements, such as increased ethanol yields with minimal carryover of biocide into co-products of the processes.Type: GrantFiled: March 16, 2011Date of Patent: February 10, 2015Assignee: Buckman Laboratories International, Inc.Inventors: Christopher L. Wiatr, Michael L. Corcoran, Thomas E. McNeel, Richard A. Clark, Rita de Cassia Bortoto Porto, David Oppong
-
Patent number: 8759300Abstract: Described herein are fragments of fibronectin and vitronectin and variants thereof that have certain activities, including growth factor-binding activity. Also described are fragments of growth factors that bind to fibronectin and inhibit binding of full-length growth factors to fibronectin. Compositions containing such fragments are useful in cosmetic treatments (e.g., the treatment of wrinkles or UV photodamage of skin), and the treatment of wounds and cancer.Type: GrantFiled: June 16, 2008Date of Patent: June 24, 2014Assignee: The Research Foundation for the State University of New YorkInventor: Richard A. Clark
-
Publication number: 20140105808Abstract: A method of controlling an exothermic or endothermic chemical reaction is provided. The method involves measuring a temperature of a first reactant flowing at a first flow rate, contacting the first reactant with a second reactant flowing at a second flow rate to form a reaction product, measuring the temperature of the reaction product, and determining the temperature difference between the temperature of the first reactant and the temperature of the reaction product. The method can further involve adjusting the flow rate of at least one of the first reactant and the second reactant, or shutting down flow, based on the temperature difference. An apparatus to carry out the method is also provided. The method and apparatus can be useful in controlling many different reactions, including the reaction of sodium hypochlorite and ammonia to form monochloramine.Type: ApplicationFiled: September 24, 2013Publication date: April 17, 2014Applicant: Buckman Laboratories International, Inc.Inventors: Thomas E. McNeel, Richard A. Clark, Richard D. Lusk, JR.
-
Patent number: 8691944Abstract: Described herein are fragments of fibronectin and variants thereof that bind growth factors. Compositions containing such a fragment of fibronectin are therefore useful in sequestering growth factors, and complexes containing both a FN fragment and a bound, active growth factor can be used to deliver growth factors to a patient (e.g., to a wound on the patient's skin).Type: GrantFiled: October 4, 2006Date of Patent: April 8, 2014Assignee: The Research Foundation for the State University of New YorkInventors: Richard A. Clark, Xiang-Dong Ren, Fubao Lin
-
Publication number: 20140088190Abstract: The present invention provides a method of treating an aqueous system for biocide control, by adding an acidified solution that includes monoalkyldithiocarbamate salt and alkyl isothiocyanate to an aqueous system. A biocide feed system is also provided that is configured to generate a reproducible level of alkyl isothiocyanate. The method and system provide effective levels of alkyl isothiocyanate for rapid biocidal activity, along with levels of monoalkyldithiocarbamate salt which can decompose to form additional alkyl isothiocyanate and provide longer-term biocidal activity.Type: ApplicationFiled: September 10, 2013Publication date: March 27, 2014Applicant: Buckman Laboratories International, Inc.Inventors: Thomas E. McNeel, Richard A. Clark, William C. Ganus, Richard D. Lusk, JR., Graciela H. Vunk, Luis A. Zugno
-
Publication number: 20130322002Abstract: A mobile computer workstation for use with a computer network is disclosed. The workstation can include a wheeled chassis having a vertical beam that supports a horizontal work surface. An input device tray is located at a front side of the work surface and a bracket located at a rear side of the work surface mounts a display screen to the workstation above and off the work surface. A power unit including a battery charger and a battery is mounted to the chassis and supplies power to the display screen.Type: ApplicationFiled: August 9, 2013Publication date: December 5, 2013Applicant: InterMetro Industries CorporationInventors: Richard A. Clark, Michael R. Jacobs, Steven B. Flemig, Fouad Geries Abu-Akel, Darin Janoschka, Keith Washington
-
Publication number: 20130292267Abstract: A method is provided for measuring an electrolytically-active species concentration in an aqueous or non-aqueous solution for use in providing control of the concentration of the species in a source solution thereof based on the measurements. In the method, a sample containing an electrolytically-active species is added into a measurement cell that has a working electrode and an auxiliary electrode, and a constant current is applied to the measurement cell while the working and auxiliary electrodes are in contact with the sample with monitoring of voltage difference across the electrodes until a change in the voltage difference is detected. A feedback signal is generated based on a parameter of the change in the voltage difference that is directly proportional to the amount of the electrolytically-active species in the sample, which can be used for process control. An apparatus is also described.Type: ApplicationFiled: April 26, 2013Publication date: November 7, 2013Applicant: Buckman Laboratories International, Inc.Inventors: Thomas E. McNeel, Richard A. Clark, Richard D. Lusk, JR., Chamindu Liyanapatirana
-
Patent number: 8526176Abstract: A mobile computer workstation for use with a computer network is disclosed. The workstation can include a wheeled chassis having a vertical beam that supports a horizontal work surface. An input device tray is located at a front side of the work surface and a bracket located at a rear side of the work surface mounts a display screen to the workstation above and off the work surface. A power unit including a battery charger and a battery is mounted to the chassis and supplies power to the display screen.Type: GrantFiled: July 26, 2011Date of Patent: September 3, 2013Assignee: InterMetro Industries CorporationInventors: Richard A. Clark, Michael R. Jacobs, Steven B. Flemig, Fouad Geries Abu-Akel, Darin Janoschka, Keith Washington
-
Publication number: 20130043194Abstract: A method and composition is described for controlling the growth of fouling materials, such as scale, in aqueous systems using a tagged (fluorescent) polymer. The tagged polymer can be a fluorescent polymer which has at least one fluorescent monomeric unit derived from a fluorophore which has at least one terminal end comprising an olefinic group. The method of controlling the growth of at least one fouling material in an aqueous system can include the steps of adding the tagged polymer to the aqueous system to be treated, fluorometrically monitoring the concentration of the tagged polymer, and adjusting, as needed, the concentration of the tagged polymer and proportionally used water treatment compound or compounds effective to control the growth of at least one fouling material. The adjustment of pH before determination of the fluorescence signal can be employed to increase sensitivity of the fluorophore and minimize background interference.Type: ApplicationFiled: July 30, 2012Publication date: February 21, 2013Applicant: BUCKMAN LABORATORIES INTERNATIONAL, INC.Inventors: Thomas E. McNeel, Marilyn S. Whittemore, Richard A. Clark, Jadwiga J. Grabowicz
-
Publication number: 20130005824Abstract: The present invention features methods of treating patient for ischemic tissue damage. The methods can be carried out by administering (e.g., intravenously administering) a curcuminoid or a pharmaceutically active salt, metabolite, or analog thereof at low doses.Type: ApplicationFiled: October 15, 2010Publication date: January 3, 2013Applicant: The Research Foundation of State University of New YorkInventors: Richard A. Clark, Adam Singer, Mary Frame McMahon
-
Publication number: 20110279958Abstract: A mobile computer workstation for use with a computer network is disclosed. The workstation can include a wheeled chassis having a vertical beam that supports a horizontal work surface. An input device tray is located at a front side of the work surface and a bracket located at a rear side of the work surface mounts a display screen to the workstation above and off the work surface. A power unit including a battery charger and a battery is mounted to the chassis and supplies power to the display screen.Type: ApplicationFiled: July 26, 2011Publication date: November 17, 2011Applicant: INTERMETRO INDUSTRIES CORPORATIONInventors: Richard A. Clark, Michael R. Jacobs, Steven B. Flemig, Fouad Abu-Akel, Darin Janoschka, Keith Washington
-
Publication number: 20110230394Abstract: Methods for controlling the growth of bacteria in ethanol fermentation systems with antibiotic alternatives, which can be nonoxidizing biocides, stabilized oxidizers, or any combinations thereof, are described. As an option, a process or composition of the present invention can include one or more polycyclic antibacterial peptides. The methods can provide improvements, such as increased ethanol yields with minimal carryover of biocide into co-products of the processes.Type: ApplicationFiled: March 16, 2011Publication date: September 22, 2011Applicant: BUCKMAN LABORATORIES INTERNATIONAL, INC.Inventors: Christopher L. Wiatr, Michael L. Corcoran, Thomas E. McNeel, Richard A. Clark, Rita de Cassia Bortoto Porto, David Oppong
-
Patent number: 7990691Abstract: A mobile workstation for use with a computer network. The mobile workstation may include a medical monitoring device, a radio transceiver in communication with the medical monitoring device operable for receiving and sending data to the computer network, a display screen, and a wheeled chassis for mounting the medical monitoring device, the radio transceiver and the display screen.Type: GrantFiled: August 6, 2010Date of Patent: August 2, 2011Assignee: InterMetro Industries CorporationInventors: Richard A. Clark, Michael R. Jacobs, Steven B. Flemig, Fouad Geries Abu-Akel, Darin Janoschka, Keith Washington