Patents by Inventor Richard A. Ewin

Richard A. Ewin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Endoparasitic depsipeptides
    Patent number: 11786575
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: October 17, 2023
    Assignee: Zoetis Services LLC
    Inventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christopher S Knauer, Rajendran Vairagoundar
  • Endoparasitic depsipeptides
    Patent number: 11771738
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2 are as defined herein. The present invention also contemplates compositions, methods of treatment, and uses as a medicament to treat an animal for an endoparasitic infection with a Formula (1) compound.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: October 3, 2023
    Assignee: Zoetis Services LLC
    Inventors: Todd Maddux, Matthew W. Bedore, Paul D. Johnson, Tomasz Respondek, Susan M. K. Sheehan, Graham M. Kyne, Richard A. Ewin, Rajendran Vairagoundar, Michael P. Curtis
  • SEROTONIN 5-HT2B INHIBITORY COMPOUNDS
    Publication number: 20230071039
    Abstract: The invention describes novel serotonin c5-HT2B receptor antagonists of Formula (1), and pharmaceutically acceptable salts thereof; wherein Ring A, L, X, X?, R3, R4, m and n are as defined herein. Also described are compositions comprising a Formula (1) compound, or a pharmaceutically acceptable salt thereof; and methods of using the compounds, or a pharmaceutically acceptable salt thereof, for the treatment of myxomatous mitral valve disease (MMVD), congestive heart failure (CHF) and/or asymptomatic heart failure in animals, preferably is a canine.
    Type: Application
    Filed: July 22, 2022
    Publication date: March 9, 2023
    Inventors: Richard A. Ewin, Ashley E. Fenwick, Govindan Subramanian
  • Endoparasitic Depsipeptides
    Publication number: 20220323540
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2 are as defined herein. The present invention also contemplates compositions, methods of treatment, and uses as a medicament to treat an animal for an endoparasitic infection with a Formula (1) compound.
    Type: Application
    Filed: May 7, 2019
    Publication date: October 13, 2022
    Inventors: Todd Maddux, Matthew W. Bedore, Paul D. Johnson, Tomasz Respondek, Susan M.K. Sheehan, Graham M. Kyne, Richard A. Ewin, Rajendran Vairagoundar, Michael P. Curtis
  • Endoparasitic Depsipeptides
    Publication number: 20220211802
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.
    Type: Application
    Filed: March 17, 2022
    Publication date: July 7, 2022
    Inventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christopher S. Knauer, Rajendran Vairagoundar
  • Endoparasitic depsipeptides
    Patent number: 11331369
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: May 17, 2022
    Assignee: Zoetis Services LLC
    Inventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christoper S. Knauer, Rajendran Vairagoundar
  • Endoparasitic Depsipeptides
    Publication number: 20200282016
    Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.
    Type: Application
    Filed: November 28, 2018
    Publication date: September 10, 2020
    Inventors: Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christoper S. Knauer, Rajendran Vairagoundar
  • Phenicol antibacterials
    Patent number: 9428528
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: August 30, 2016
    Assignee: Zoetis Services LLC
    Inventors: Michael Curtis, Richard A Ewin, Timothy Allan Johnson, Susan M. K. Sheehan
  • PHENICOL ANTIBACTERIALS
    Publication number: 20160194342
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Application
    Filed: March 16, 2016
    Publication date: July 7, 2016
    Inventors: Michael Curtis, Richard A Ewin, Timothy Allan Johnson, Susan M.K. Sheehan
  • Phenicol antibacterials
    Patent number: 9340564
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: May 17, 2016
    Assignee: Zoetis Services LLC
    Inventors: Richard A. Ewin, Timothy Allan Johnson, Susan M. K. Sheehan
  • PHENICOL ANTIBACTERIALS
    Publication number: 20150266910
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Application
    Filed: June 5, 2015
    Publication date: September 24, 2015
    Inventors: Michael Curtis, Brian A. Duclos, Richard A. Ewin, Paul D. Johnson, Timothy Allan Johnson, Rajendran Vairagoundar, Denis Billen, Richard M. Goodwin, Andrea K. Haber-Stuk, Graham M. Kyne, Susan M. K. Sheehan
  • Phenicol antibacterials
    Patent number: 9073894
    Abstract: The present invention provides novel phenicol derivatives of formula I their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: July 7, 2015
    Assignee: Zoetis Services LLC
    Inventors: Richard A. Ewin, Timothy Allan Johnson, Susan M. K. Sheehan
  • Cephalosporins useful as antibacterial agents
    Patent number: 8722656
    Abstract: The present invention provides novel cephalosporin derivatives of formula I, their analogues, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: May 13, 2014
    Assignee: Zoetis LLC
    Inventors: Brian A. Duclos, Edmund L. Ellsworth, Richard A. Ewin, Paul D. Johnson, Timothy A. Johnson, Graham M. Kyne, Susan M. K. Sheehan, Rajendran Vairagoundar
  • PHENICOL ANTIBACTERIALS
    Publication number: 20130237502
    Abstract: The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Application
    Filed: March 5, 2013
    Publication date: September 12, 2013
    Inventors: Michael Curtis, Brian A. Duclos, Richard A. Ewin, Paul D. Johnson, Timothy Allen Johnson, Rajendran Vairagoundar, Denis Billen, Richard M. Goodwin, Andrea K. Haber-Stuk, Graham M. Kyne, Susan M. K. Sheehan
  • NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS
    Publication number: 20120283237
    Abstract: The present invention provides novel cephalosporin derivatives of formula I, their analogues, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
    Type: Application
    Filed: April 30, 2012
    Publication date: November 8, 2012
    Applicant: PFIZER INC.
    Inventors: Brian A. Duclos, Edmund L. Ellsworth, Richard A. Ewin, Paul D. Johnson, Timothy A. Johnson, Graham M. Kyne, Susan M. K. Sheehan, Rajendran Vairagoundar