Patents by Inventor Richard A. Graff

Richard A. Graff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110280963
    Abstract: The present invention provides methods of sensitizing lung cancer cells to cisplatin and inhibiting the growth of lung cancer tumors by employing a modified eIF-4E antisense oligonucleotide and cisplatin in combination.
    Type: Application
    Filed: November 17, 2009
    Publication date: November 17, 2011
    Applicant: Isis Pharmaceuticals, Inc.
    Inventor: Jeremy Richard Graff
  • Publication number: 20110246243
    Abstract: Machine for controlling a system changing electrical signals to separately value components temporally decomposed from residential property, the computer apparatus including: a computer system, arranged for receiving information into a memory, the data representing the residential property, the computer system further comprising: logic means controlling the computer system to change the data to produce modified signals representing a separate valuation of each of a plurality of components temporally decomposed from the residential property, the components including a residential estate for years interest and a residential remainder interest; and an output device connected to convert the modified signals into documentation including the respective valuation of each of the components.
    Type: Application
    Filed: November 19, 2004
    Publication date: October 6, 2011
    Inventor: Richard A. Graff
  • Patent number: 7908202
    Abstract: An electronic system, the system for selling fixed income instruments, the system including a second computer having an output device and at least one buyer's computer having an electrically coupled input device and a monitor, the buyer's computer and the second computer being respectively located, the computers being used in cooperation in a multiple computer system in electronically communicating data between the computers.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: March 15, 2011
    Assignee: Graff/Ross Holdings, LLP
    Inventor: Richard A. Graff
  • Patent number: 7865416
    Abstract: Illustratively, there can be a securitization system that is comprised of a computer or computers using a network, and a process, for the conversion of assets into marketable securities. In one embodiment, the securitization system includes a distribution system to distribute at least some of the marketable securities generated by the securitization system to one or more buyers. The process may utilize a new definition of securitization that expands the universe of securitizable assets, the universe of asset securitization methodologies, and the universe of securities that can be designed and generated thereby.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: January 4, 2011
    Assignee: Ross/Graff Holdings LLC
    Inventors: Richard A. Graff, James M. McKevitt
  • Publication number: 20100241594
    Abstract: An apparatus and process, including an electronic system, the system for generating output in selling fixed income instruments, the system including a first computer system having an output device and at least one other computer system having an input device, the first computer system and the other computer system being respectively located, the computer systems being used in cooperation in a multiple computer system in electronically communicating data between the computer systems.
    Type: Application
    Filed: June 2, 2010
    Publication date: September 23, 2010
    Applicant: GRAFF/ROSS HOLDINGS, LLP
    Inventor: Richard A. Graff
  • Publication number: 20100130589
    Abstract: Oligomeric compounds, compositions and methods are provided for modulating the expression of eIF4E. The antisense compounds may be single- or double-stranded and are targeted to nucleic acid encoding eIF4E. Methods of using these compounds for modulation of eIF4E expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E are provided.
    Type: Application
    Filed: August 31, 2009
    Publication date: May 27, 2010
    Inventors: Susan M. Freier, Kenneth Dobie, Eric G. Marcusson, Eric E. Swayze, Balkrishen Bhat, Jeremy Richard Graff, Bruce William Konicek
  • Patent number: 7685053
    Abstract: An electronic system, the system for selling fixed income instruments, the system including a second computer having an output device and at least one buyer's computer having an electrically coupled input device and a monitor, the buyer's computer and the second computer being respectively located, the computers being used in cooperation in a multiple computer system in electronically communicating data between the computers.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: March 23, 2010
    Assignee: Graff/Ross Holdings, LLP
    Inventor: Richard A. Graff
  • Patent number: 7601700
    Abstract: Oligomeric compounds, compositions and methods are provided for modulating the expression of eIF4E. The antisense compounds may be single- or double-stranded and are targeted to nucleic acid encoding eIF4E. Methods of using these compounds for modulation of eIF4E expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E are provided.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: October 13, 2009
    Assignees: Eli Lilly and Company, ISIS Pharmaceuticals, Inc.
    Inventors: Kenneth Dobie, Eric G. Marcusson, Eric E. Swayze, Balkrishen Bhat, Jeremy Richard Graff
  • Publication number: 20090192106
    Abstract: Oligomeric compounds, compositions and methods are provided for modulating the expression of eIF4E. The antisense compounds may be single- or double-stranded and are targeted to nucleic acid encoding eIF4E. Methods of using these compounds for modulation of eIF4E expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E are provided.
    Type: Application
    Filed: August 1, 2008
    Publication date: July 30, 2009
    Inventors: Kenneth Dobie, Eric G. Marcusson, Eric E. Swayze, Balkrishen Bhat, Jeremy Richard Graff
  • Patent number: 7505934
    Abstract: Computer machine, manufacture, methods of making and using the same, and product produced thereby, each pertaining to valuing, trading, and/or documenting securities that produce mostly tax-exempt income. A method includes making a second financial analysis output having a second computed valuation for property, the financial analysis output being made by steps including: controlling a computer in generating as output a valuation for an income-producing security, the security not a tax-exempt security, most of the income produced by the security being tax-exempt; communicating some of the output to a second computer for generating the second valuation; and generating the second financial analysis output, including the second valuation, at the second computer.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: March 17, 2009
    Assignee: Graff/Ross Holdings LLP
    Inventor: Richard A. Graff
  • Publication number: 20080235120
    Abstract: An electronic system, the system for selling fixed income instruments, the system including a second computer having an output device and at least one buyer's computer having an electrically coupled input device and a monitor, the buyer's computer and the second computer being respectively located, the computers being used in cooperation in a multiple computer system in electronically communicating data between the computers.
    Type: Application
    Filed: March 24, 2005
    Publication date: September 25, 2008
    Applicant: Graff/Ross Holdings, LLP
    Inventor: Richard Graff
  • Patent number: 7425544
    Abstract: Oligomeric compounds, compositions and methods are provided for modulating the expression of eIF4E. The antisense compounds may be single- or double-stranded and are targeted to nucleic acid encoding eIF4E. Methods of using these compounds for modulation of eIF4E expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E are provided.
    Type: Grant
    Filed: September 17, 2004
    Date of Patent: September 16, 2008
    Assignees: Eli Lilly and Company, ISIS Pharmaceuticals, Inc.
    Inventors: Kenneth Dobie, Eric G. Marcusson, Eric E. Swayze, Balkrishen Bhat, Jeremy Richard Graff
  • Publication number: 20080120247
    Abstract: An electronic system, the system for selling fixed income instruments, the system including a second computer having an output device and at least one buyer's computer having an electrically coupled input device and a monitor, the buyer's computer and the second computer being respectively located, the computers being used in cooperation in a multiple computer system in electronically communicating data between the computers.
    Type: Application
    Filed: November 14, 2006
    Publication date: May 22, 2008
    Inventor: Richard A. Graff
  • Publication number: 20080091476
    Abstract: Machine for controlling a system changing electrical signals to separately value components temporally decomposed from residential property, the computer apparatus including: a computer system, arranged for receiving information into a memory, the data representing the residential property, the computer system further comprising: logic means controlling the computer system to change the data to produce modified signals representing a separate valuation of each of a plurality of components temporally decomposed from the residential property, the components including a residential estate for years interest and a residential remainder interest; and an output device connected to convert the modified signals into documentation including the respective valuation of each of the components.
    Type: Application
    Filed: November 19, 2004
    Publication date: April 17, 2008
    Inventor: Richard A. Graff
  • Patent number: 7295987
    Abstract: A computer system for changing signals to separately value components temporally decomposed from residential property, the computer system including: an input device operable for converting input data representing the residential property into input signals representing the input data; a computer having a processor, the processor connected to the input to receive the input computer signals, the processor programmed to change the input signals to produce modified signals representing a separate market-based valuation of each of a plurality of components temporally decomposed from the property, the components including a residential estate for years interest and a residential remainder interest; and an output device connected to the processor to convert the modified signals into an illustration including the respective valuation of each of the components.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: November 13, 2007
    Assignee: Graff/Ross Holdings LLP
    Inventor: Richard A. Graff
  • Patent number: 7203661
    Abstract: A computer system, and methods for making and using it, for manipulating digital electrical signals to produce an illustration of a decomposition of property into separately valued components. The computer system includes a digital electrical computer controlled by a processor. There is a first logic means controlling the processor in manipulating digital electrical signals representing input data to the computer, the input data characterizing at least two components decomposed from the property, the manipulating including transforming the digital electrical signals into modified digital electrical signals representing respective values for each of the components, the values being computed to reflect taxation for the components. Input means is coupled to the computer and operable for converting the input data into the digital electrical signals and communicating the digital electrical signals to the computer.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: April 10, 2007
    Assignee: Graff/Ross Holdings
    Inventor: Richard A. Graff
  • Patent number: 7152044
    Abstract: An electronic system, the system for selling fixed income instruments, the system including a second computer having an output device and at least one buyer's computer having an electrically coupled input device and a monitor, the buyer's computer and the second computer being respectively located, the computers being used in cooperation in a multiple computer system in electronically communicating data between the computers.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: December 19, 2006
    Assignee: Graff/Ross Holdings
    Inventor: Richard A. Graff
  • Patent number: 7107239
    Abstract: A computer and methods for valuing components temporally decomposed from property, and for producing documentation, including tax and insurance. In one variation, there is a separate market-based valuation of each of a plurality of components temporally decomposed from the property, the components including an estate for years interest and a remainder interest.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: September 12, 2006
    Assignee: Graff-Ross Holdings
    Inventor: Richard A. Graff
  • Patent number: 7044052
    Abstract: The present invention disclosed herein provides a transportable recycling center (10) that has a container (12) and a partition (18) within the container (12). The partition (18) separates a work area (20) from a storage area (22). An attendant may accept recyclable materials from consumers in the work area (20) and store the recyclable material in the storage area (22). After the container (12) has been filled with recyclable material, doors (14, 16) on the container (12) may be secured and the container (12) may be loaded onto a truck and transported to a recycling facility.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: May 16, 2006
    Assignee: Nexcycle, Inc.
    Inventors: Hans Van Der Touw, Mathew Millhiser, Richard Graff
  • Publication number: 20050222930
    Abstract: An electronic system, the system for selling fixed income instruments, the system including a second computer having an output device and at least one buyer's computer having an electrically coupled input device and a monitor, the buyer's computer and the second computer being respectively located, the computers being used in cooperation in a multiple computer system in electronically communicating data between the computers.
    Type: Application
    Filed: March 24, 2005
    Publication date: October 6, 2005
    Inventor: Richard Graff