Abstract: A method for inhibitory and bactericidal activities against human pathogens by n-alkyl chain length of modified sophorolipid n-alkyl esters, and preferred n-alkyl chain lengths to enhance sophorolipid n-alkyl ester inhibitory and bactericidal activities against human pathogens.

Abstract: A method for the development of a library of modified sophorolipids using a wide-range of chemical and enzyme catalyst tools to identify modified sophorolipids that can be used in pure form, as mixtures with other modified sophorolipids, as mixtures with natural sophorolipids, as mixtures with modified and natural sophorolipids, and as mixtures with other compounds known by one skilled in the art for use in the dispersion, solubilization or emulsification of various oil types and nutraceuticals, and modified sophorolipids for use in dispersion, solubilization or emulsification processes.

Abstract: A flex hinge closure with a drain-back channel includes a base portion having a dispensing aperture, a raised pour lip formed along a perimeter of the dispensing aperture, a raised rib forming a closed shape surrounding the raised pour lip, and a drain-back channel defined by a space between the raised pour lip and the raised rib. The drain-back channel collects excess material dispensed via the dispensing aperture and drains the excess material back to a receptacle. The closure further includes a cap portion hingedly connected to the base portion. The cap portion rotates relative to the base portion about the hinged connection between a closed position in which the cap portion covers the dispensing aperture and an open position in which the cap portion uncovers the dispensing aperture.

Abstract: A method for producing sophorolipids having protein inducer and/or repressor activities having the steps of synthesizing the sophorolipid by fermentation of Candida bombicola in a fermentation media to form a natural mixture of lactonic sophorolipids and non-lactonic sophorolipids and then utilizing the natural mixture as a protein inducing agent, utilizing the natural mixture as a protein repressing agent, and/or utilizing the natural mixture as a combined protein induction/repressor agent. An application of the sophorolipid compound produced according to the method as a microbial media component.

Abstract: A flex hinge closure with a drain-back channel is provided. The closure includes a base portion having a dispensing aperture, a raised pour lip formed along a perimeter of the dispensing aperture, a raised rib forming a closed shape surrounding the raised pour lip, and a drain-back channel defined by a space between the raised pour lip and the raised rib. The drain-back channel is configured to collect excess material dispensed via the dispensing aperture and to drain the excess material back to a receptacle. The closure further includes a cap portion hingedly connected to the base portion. The cap portion is configured to rotate relative to the base portion about the hinged connection between a closed position in which the cap portion covers the dispensing aperture and an open position in which the cap portion uncovers the dispensing aperture.

Abstract: A composition of matter comprising sophorolipids as antimicrobial agents, antifungal agents, biopesticides, for uses as drugs to treat HIV, septic shock, cancer, asthma, dermatological conditions, as spermicidal agents, as anti-inflammatory drugs, as ingredients in cosmetics and building blocks for monomers and polymers and self-assembled templates for further chemical elaboration.

Abstract: A method for producing sophorolipids having protein inducer and/or repressor activities having the steps of synthesizing the sophorolipid by fermentation of Candida bombicola in a fermentation media to form a natural mixture of lactonic sophorolipids and non-lactonic sophorolipids and then utilizing the natural mixture as a protein inducing agent, utilizing the natural mixture as a protein repressing agent, and/or utilizing the natural mixture as a combined protein induction/repressor agent. An application of the sophorolipid compound produced according to the method as a microbial media component.

Abstract: 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octa-decenoate, lactonic and open ring 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, methyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, ethyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, hexyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, ethyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate-6?-acetate and ethyl 17-L-[(2?-O-?-D-glucopyranosyl-?-D-glucopyranosyl)-oxy]-cis-9-octadecenoate-6?,6?-diacetate sophorolipids and uses thereof as antifungal agents.

Abstract: A container provides sealed storage for contents. The container includes a composite top member formed of a panel and a frame. The panel includes an opening for providing access to the contents of the package. The frame includes a closure member that is molded in an open position, and which can be moved to a closed position for closing the opening in the panel. The container is formed of a container body in the form of a tubular member formed to a desired shape. The container body is closed using the top member that closes a top opening of the container body, and a bottom member that closes a bottom opening of the container body.

Abstract: A composition of matter comprising sophorolipids as antimicrobial agents, antifungal agents, biopesticides, for uses as drugs to treat HIV, septic shock, cancer, asthma, dermatological conditions, as spermicidal agents, as anti-inflammatory drugs, as ingredients in cosmetics and building blocks for monomers and polymers and self-assembled templates for further chemical elaboration.

Abstract: The present invention relates to aliphatic or aliphatic-aromatic polyesters and copolyesters comprised of biobased ?-hydroxyfatty acids or derivatives thereof, processes for the preparation thereof, and compositions thereof having improved properties. The copolyesters of the present invention may also contain additional components that can be selected from aliphatic or aromatic diacids, diols and hydroxyacids obtained from synthetic and natural sources. The biobased ?-hydroxyfatty acids that comprise the polyesters and copolyesters of the present invention are made using a fermentation process from pure fatty acids, fatty acid mixtures, pure fatty acid ester, mixtures of fatty acid esters, and triglycerides from various sources. The polyesters of the present invention may contain various amounts and types of ?-carboxyfatty acids depending on the engineered yeast strain used for the bioconversion as well as the feedstock(s) used.

Abstract: A method for neutralizing or inactivating a virus, and neutralizing or inactivating HIV using sophorolipids having antiviral properties produced by synthesizing the sophorolipid by fermentation of Candida bombicola in a fermentation media to form a natural mixture of lactonic sophorolipids compounds and non-lactonic sophorolipids compounds and utilizing the natural mixture as an antiviral agent, and/or separating the lactonic sophorolipids from the natural mixture to form a lactonic fraction and mixing all remaining fractions to form a non-lactonic fraction and utilizing the lactonic fraction and/or the non-lactonic fraction as an antiviral agent, and sophorolipid compounds for use as antiviral agents.

Abstract: Cap can include a cap body mountable to a container. A main bore is disposed in the cap body. A movable component holder has a lower end, an upper end, and a space sized and configured to contain a dispensable component. At least a first seal provides sealing between an inner surface of the cap body and an outer surface of the component holder. The first seal at least one of is disposed on a generally circumferential wall and is located axially above an annular upper wall of the cap body, is arranged on a generally circumferential wall that can deflect slightly radially outwardly, projects from the inner surface of the cap body, is axially fixed to the inner surface of the cap body, is disposed at an upper end of the main bore, is arranged above an uppermost annular surface of the cap body, is slidably engageable with an outer circumferential surface of the component holder, is located adjacent an upper end of an inner tubular section of the cap body.

Abstract: A composition of matter comprising sophorolipids as antimicrobial agents, antifungal agents, biopesticides, for uses as drugs to treat HIV, septic shock, cancer, asthma, dermatological conditions, as spermicidal agents, as anti-inflammatory drugs, as ingredients in cosmetics and building blocks for monomers and polymers and self-assembled templates for further chemical elaboration.

Abstract: A method for the development of a library of modified sophorolipids using a wide-range of chemical and enzyme catalyst tools to identify modified sophorolipids that can be used in pure form, as mixtures with other modified sophorolipids, as mixtures with natural sophorolipids, as mixtures with modified and natural sophorolipids, and as mixtures with other compounds known by one skilled in the art for use in the dispersion, solubilization or emulsification of various oil types and nutraceuticals, and modified sophorolipids for use in dispersion, solubilization or emulsification processes.

Abstract: The present invention relates to polyurethane polymers comprising as part of its polymer backbone biobased ?-hydroxyfatty acids or derivatives thereof, processes for the preparation thereof, and compositions thereof having improved properties. The polyurethanes of the present invention are prepared from copolyester prepolymers comprising the biobased ?-hydroxyfatty acids that may also contain additional components that can be selected from aliphatic or aromatic diacids, diols and hydroxyacids obtained from synthetic and natural sources. The biobased ?-hydroxyfatty acids that comprise the polyurethanes and copolyester prepolymers of the present invention are made using a fermentation process from pure fatty acids, fatty acid mixtures, pure fatty acid ester, mixtures of fatty acid esters, and triglycerides from various sources.

Abstract: A biodegradable material, capable of carrying a bioactive agent, comprising a polymer matrix and an enzyme capable of degrading the polymer matrix to enable the release of the bioactive agent.

Abstract: A container provides sealed storage for contents. The container includes a composite top member formed of a panel and a frame. The panel includes an opening for providing access to the contents of the package. The frame includes a closure member that is molded in an open position, and which can be moved to a closed position for closing the opening in the panel. The container is formed of a container body in the form of a tubular member formed to a desired shape. The container body is closed using the top member that closes a top opening of the container body, and a bottom member that closes a bottom opening of the container body.

Abstract: A process for preparing unique peptide mixtures with a broad range of uses using combinations of natural and non-natural amino acid alkyl ester monomers and specific combinations of these monomers as dimers, trimers and higher oligomers selected from the large group of structural motifs that lead to useful physical and/or biological properties and that have been or may be identified from solid state peptide synthesis, isolation of peptides from natural sources, and production of peptides by recombinant DNA methods, or identification of peptides by recombinant methods such as phage display, the method of peptide synthesis comprising a) admixing one or more natural and non-natural amino acid alkyl ester monomer, dimer, trimer and higher oligomers with one or more proteases in a reaction medium; b) heating the mixture to between about 5° C. to about 90° C. for between 5 minutes and 24 hours; and c) recovering the formed oligopeptide.

Abstract: A method for neutralizing or inactivating a virus, and neutralizing or inactivating HIV using sophorolipids having antiviral properties produced by synthesizing the sophorolipid by fermentation of Candida bombicola in a fermentation media to form a natural mixture of lactonic sophorolipids compounds and non-lactonic sophorolipids compounds and utilizing the natural mixture as an antiviral agent, and/or separating the lactonic sophorolipids from the natural mixture to form a lactonic fraction and mixing all remaining fractions to form a non-lactonic fraction and utilizing the lactonic fraction and/or the non-lactonic fraction as an antiviral agent, and sophorolipid compounds for use as antiviral agents.