Patents by Inventor Richard A. Reitz

Richard A. Reitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quantitation of insulin-like growth factor-I and insulin-like growth factor-II with high-resolution mass spectrometry
    Patent number: 11953507
    Abstract: Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.
    Type: Grant
    Filed: September 21, 2022
    Date of Patent: April 9, 2024
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Cory Bystrom, Shijun Sheng, Nigel Clarke, Richard Reitz
  • QUANTITATION OF INSULIN-LIKE GROWTH FACTOR-I AND INSULIN-LIKE GROWTH FACTOR-II WITH HIGH-RESOLUTION MASS SPECTROMETRY
    Publication number: 20230324414
    Abstract: Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution / high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution / high accuracy mass spectrometry.
    Type: Application
    Filed: April 7, 2023
    Publication date: October 12, 2023
    Applicant: Quest Diagnostics Investments Incorporated
    Inventors: Cory Bystrom, Shijun Sheng, Nigel Clarke, Richard Reitz
  • QUANTITATION OF INSULIN-LIKE GROWTH FACTOR-I AND INSULIN-LIKE GROWTH FACTOR-II WITH HIGH-RESOLUTION MASS SPECTROMETRY
    Publication number: 20230039315
    Abstract: Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.
    Type: Application
    Filed: September 21, 2022
    Publication date: February 9, 2023
    Inventors: Cory Bystrom, Shijun Sheng, Nigel Clarke, Richard Reitz
  • Mass spectrometry method for measuring vitamin B6 in body fluids
    Patent number: 9234901
    Abstract: Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5?-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: January 12, 2016
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Qibo Jiang, Sum Chan, Richard Reitz
  • Methods for detecting dihydrotestosterone by mass spectrometry
    Patent number: 8410428
    Abstract: Provided are methods for determining the amount of dihydrotestosterone (DHT) in a sample using mass spectrometry. The methods generally involve ionizing DHT in a sample and detecting and quantifying the amount of the ion to determine the amount of DHT in the sample.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: April 2, 2013
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Amit Ghoshal, Nigel J. Clarke, Richard Reitz
  • Methods for detecting vitamin C by mass spectrometry
    Patent number: 8338778
    Abstract: Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample.
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: December 25, 2012
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Qibo Jiang, Richard Reitz, Sum Chan
  • METHODS FOR DETECTING DIHYDROTESTOSTERONE BY MASS SPECTROMETRY
    Publication number: 20120175517
    Abstract: Provided are methods for determining the amount of dihydrotestosterone (DHT) in a sample using mass spectrometry. The methods generally involve ionizing DHT in a sample and detecting and quantifying the amount of the ion to determine the amount of DHT in the sample.
    Type: Application
    Filed: March 21, 2012
    Publication date: July 12, 2012
    Inventors: Amit Ghoshal, Nigel J. Clarke, Richard Reitz
  • Methods for detecting dihydrotestosterone by mass spectrometry
    Patent number: 8158931
    Abstract: Provided are methods for determining the amount of dihydrotestosterone (DHT) in a sample using mass spectrometry. The methods generally involve ionizing DHT in a sample and detecting and quantifying the amount of the ion to determine the amount of DHT in the sample.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: April 17, 2012
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Amit Ghoshal, Nigel J. Clarke, Richard Reitz
  • MASS SPECTROMETRY METHOD FOR MEASURING VITAMIN B6 IN BODY FLUIDS
    Publication number: 20110297825
    Abstract: Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5?-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography.
    Type: Application
    Filed: August 11, 2011
    Publication date: December 8, 2011
    Inventors: Qibo Jiang, Sum Chan, Richard Reitz
  • Mass spectrometry method for measuring vitamin B6 in body fluid
    Patent number: 8017403
    Abstract: Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5?-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography.
    Type: Grant
    Filed: June 14, 2007
    Date of Patent: September 13, 2011
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Qibo Jiang, Sum Chan, Richard Reitz
  • METHODS FOR DETECTING VITAMIN C BY MASS SPECTROMETRY
    Publication number: 20110179855
    Abstract: Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample.
    Type: Application
    Filed: April 1, 2011
    Publication date: July 28, 2011
    Inventors: Qibo Jiang, Richard Reitz, Sum Chan
  • Methods for detecting vitamin C by mass spectrometry
    Patent number: 7952067
    Abstract: Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample.
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: May 31, 2011
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Qibo Jiang, Richard Reitz, Sum Chan
  • QUANTITATION OF INSULIN-LIKE GROWTH FACTOR-I AND INSULIN-LIKE GROWTH FACTOR-II WITH HIGH-RESOLUTION MASS SPECTROMETRY
    Publication number: 20110111512
    Abstract: Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.
    Type: Application
    Filed: November 4, 2010
    Publication date: May 12, 2011
    Inventors: Cory Bystrom, Shijun Sheng, Nigel Clarke, Richard Reitz
  • METHODS FOR DETECTING DIHYDROTESTOSTERONE BY MASS SPECTROMETRY
    Publication number: 20110006197
    Abstract: Provided are methods for determining the amount of dihydrotestosterone (DHT) in a sample using mass spectrometry. The methods generally involve ionizing DHT in a sample and detecting and quantifying the amount of the ion to determine the amount of DHT in the sample.
    Type: Application
    Filed: August 5, 2010
    Publication date: January 13, 2011
    Inventors: Amit Ghoshal, Nigel J. Clarke, Richard Reitz
  • Methods for detecting dihydrotestosterone by mass spectrometry
    Patent number: 7804063
    Abstract: Provided are methods for determining the amount of dihydrotestosterone (DHT) in a sample using mass spectrometry. The methods generally involve ionizing DHT in a sample and detecting and quantifying the amount of the ion to determine the amount of DHT in the sample.
    Type: Grant
    Filed: November 17, 2008
    Date of Patent: September 28, 2010
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Amit Ghoshal, Nigel J. Clarke, Richard Reitz
  • Methods for Detecting Vitamin C by Mass Spectrometry
    Publication number: 20100084545
    Abstract: Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample.
    Type: Application
    Filed: November 12, 2008
    Publication date: April 8, 2010
    Inventors: Qibo Jiang, Richard Reitz, Sum Chan
  • METHODS FOR DETECTING DIHYDROTESTOSTERONE BY MASS SPECTROMETRY
    Publication number: 20100084546
    Abstract: Provided are methods for determining the amount of dihydrotestosterone (DHT) in a sample using mass spectrometry. The methods generally involve ionizing DHT in a sample and detecting and quantifying the amount of the ion to determine the amount of DHT in the sample.
    Type: Application
    Filed: November 17, 2008
    Publication date: April 8, 2010
    Inventors: Amit Ghoshal, Nigel J. Clarke, Richard Reitz
  • MASS SPECTROMETRY METHOD FOR MEASURING THIAMINE IN BODY FLUID
    Publication number: 20090093009
    Abstract: Provided are methods for determining the amount of total thiamine in a body fluid sample using liquid chromatography and mass spectrometry. Total thiamine is converted to free thiamine by treatment with an acid phosphatase prior to thiamine separation and quantification.
    Type: Application
    Filed: October 9, 2007
    Publication date: April 9, 2009
    Inventors: Sum Chan, Qibo Jiang, Richard Reitz
  • Mass Spectrometry Method for Measuring Vitamin B6 in Body Fluid
    Publication number: 20080311671
    Abstract: Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5?-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography.
    Type: Application
    Filed: June 14, 2007
    Publication date: December 18, 2008
    Inventors: Qibo Jiang, Sum Chan, Richard Reitz
  • Methods for detecting vitamin D metabolites
    Publication number: 20060228808
    Abstract: Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.
    Type: Application
    Filed: April 6, 2005
    Publication date: October 12, 2006
    Inventors: Nigel Clarke, Brett Holmquist, Kwang-Ja Lee, Richard Reitz