Patents by Inventor Richard A. Shimkets

Richard A. Shimkets has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel proteins and nucleic acids encoding same
    Publication number: 20040010118
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: August 15, 2001
    Publication date: January 15, 2004
    Inventors: Bryan D. Zerhusen, Muralidhara Padigaru, Kimberly Spytek, Steven Spaderna, Esha A. Gangolli, Luca Rastelli, Catherine E. Burgess, Kumud Majumder, Richard Shimkets, Vishnu Mishra, Corine Vernet, Edward S. Szekeres, William M. Grosse, John P. Alsobrook, Xiaohong Liu, Valerie L. Gerlach, Karen Ellerman, Glennda Smithson, John Peyman, David Stone, John MacDougall
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040010119
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: February 12, 2002
    Publication date: January 15, 2004
    Inventors: Xiaojia Guo, Elma Fernandes, Li Li, Ramesh Kekuda, Yi Liu, Mario Leite, Kimberly A. Spytek, Weizhen Ji, Stacie J. Casman, Ference L. Boldog, Meera Patturajan, Corine A. M. Vernet, Robert A. Ballinger, Uriel M. Malyankar, Velizar T. Tchernev, Angela D. Blalock, Vladimir Y. Gusev, Luca Rastelli, Peter D. Mezes, Karen Ellerman, Melvyn Heyes, John L. Herrmann, Richard A. Shimkets, Noelle Ioime, Carol E. A. Pena, Suresh G. Shenoy, Raymond J. Taupier, Valerie Gerlach, Linda Gorman
  • Novel human polynucleotides and polypeptides encoded thereby
    Publication number: 20040009474
    Abstract: The present invention provides ORFX, a novel isolated polypeptide, as well as a polynucleotide encoding ORFX and antibodies that immunospecifically bind to ORFX or any derivative, variant, mutant, or fragment of the ORFX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the ORFX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to others uses.
    Type: Application
    Filed: May 24, 2001
    Publication date: January 15, 2004
    Inventors: Martin D. Leach, Richard A. Shimkets
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040009480
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: June 3, 2002
    Publication date: January 15, 2004
    Inventors: David W. Anderson, Jason C. Baumgartner, Ferenc L. Boldog, Stacie J. Casman, Shlomit R. Edinger, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Xiaojia Sasha Guo, Tord Hjalt, Ramesh Kekuda, Li Li, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Richard A. Shimkets, David J. Stone, Kimberly A. Spytek, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen
  • Proteins, polynucleotides ecoding them and methods of using the same
    Publication number: 20040005558
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 18, 2002
    Publication date: January 8, 2004
    Inventors: David W. Anderson, Catherine E. Burgess, Stacie J. Casman, Steven D. Colman, Shlomit R. Edinger, Karen Ellerman, Valerie Gerlach, Erik Gunther, Ramesh Kekuda, John R. MacDougall, Fuad Mehraban, Meera Patturajan, Mark Rothenberg, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Corine A.M. Vernet, Bryan D. Zerhusen
  • Proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20040005557
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 16, 2002
    Publication date: January 8, 2004
    Inventors: Muralidhara Padigaru, John P. Alsobrook, Steven D. Colman, Kimberly A. Spytek, Ferenc L. Boldog, Corine A.M. Vernet, Li Li, Suresh G. Shenoy, Stacie J. Casman, Xiaojia (Sasha) Guo, Shlomit R. Edinger, John R. MacDougall, Uriel M. Malyankar, Meera Patturajan, Richard A. Shimkets, Carol E. A. Pena, Velizar T. Tchernev, Bryan D. Zerhusen, Isabelle Millet, Charles E. Miller, Denise M. Lepley, Glennda Smithson, Jason C. Baumgartner, John L. Herrmann, John A. Peyman, Linda Gorman, Peter D. Mezes, Ramesh Kekuda, Raymond J. Taupier, Valerie Gerlach, William M. Grosse, Xiaohong Liu, Karen Ellerman, Mark Rothenberg, David J. Stone, Catherine E. Burgess
  • Proteins and nucleic acids encoding same
    Publication number: 20040005576
    Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: August 30, 2002
    Publication date: January 8, 2004
    Inventors: Xiaojia (Sasha) Guo, Li Li, Meera Patturajan, Richard A. Shimkets, Stacie J. Casman, Uriel M. Malyankar, Velizar T. Tchernev, Corine A. Vernet, Kimberly A. Spytek, Suresh G. Shenoy, John P. Alsobrook, Schlomit Edinger, John A. Peyman, David J. Stone, Karen Ellerman, Esha A. Gangolli, Ferenc L. Boldog, Steven D. Colman, Andrew Eisen, Xiaohong Liu, Muralidhara Padigaru, Steven K. Spaderna, Bryan D. Zerhusen
  • Treatment of inflammatory bowel disease using growth factors
    Publication number: 20040006015
    Abstract: The present invention is based upon methods of treating inflammatory conditions in the intestinal tract of mammals using growth factor related polypeptides. The invention includes methods of reducing the mortality rate or delaying mortality in a subject suffering from an inflammatory pathology. Methods of using fibroblast growth factor-CX (FGF-CX) polynucleotides sequences and the FGF-CX polypeptides encoded by such nucleic acid sequence, or variants, fragments and homologs thereof, are claimed in the invention. Similarly, methods of using FCTRX polynucleotide sequences and the FCTRX polypeptides encoded by such nucleic acid sequences, or variants, fragments and homologs thereof, alone or in combination, are also claimed in the invention. FCTRX collectively refers to any of six variant FCTRX sequences, variously designated FCTR1, FCTR2, FCTR3, FCTR4, FCTR5 and FCTR6.
    Type: Application
    Filed: December 16, 2002
    Publication date: January 8, 2004
    Inventors: Ferenc L. Boldog, Catherine E. Burgess, Elma R. Fernandes, Michael E. Jeffers, William J. LaRochelle, Henri S. Lichenstein, Jeffrey Peterson, Sudhirdas K. Prayaga, Beth Rittman, Juliette B. Shimkets, Richard A. Shimkets, Meijia Yang
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040006205
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: April 2, 2002
    Publication date: January 8, 2004
    Inventors: Li Li, Valerie Gerlach, Xiaohong Liu, Charles E. Miller, Kimberly A. Spytek, Bryan D. Zerhusen, Carol E. A. Pena, Suresh G. Shenoy, Haihong Zhong, Glennda Smithson, Stacie J. Casman, Ferenc L. Boldog, Edward Z. Voss, Corine A. Vernet, John R. MacDougall, Luca Rastelli, David W. Anderson, Mei Zhong, Peter S. Mezes, Katarzyna Furtak, Meera Patturajan, Catherine E. Burgess, Uriel M. Malyankar, Richard A. Shimkets, Raymond J. Taupier, Schlomit Edinger, Ann Mazur
  • Proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20040002584
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: February 21, 2002
    Publication date: January 1, 2004
    Inventors: Carol E. A. Pena, Richard A. Shimkets, Li Li, Suresh G. Shenoy, Ramesh Kekuda, Kimberly A. Spytek, Corine A.M. Vernet, Uriel M. Malyankar, Xiaojia (Sasha) Guo, Vladimir Y. Gusev, Stacie J. Casman, Ferenc L. Boldog, Katarzyna Furtak, Velizar T. Tchernev, Meera Patturajan, Esha A. Gangolli, Muralidhara Padigaru, Xiaohong Liu, Jason C. Baumgartner, Valerie Gerlach, Steven K. Spaderna, Bryan D. Zerhusen
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040002120
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 7, 2002
    Publication date: January 1, 2004
    Inventors: Ramesh Kekuda, Velizar T. Tchernev, Xiaohong Liu, Kimberly A. Spytek, Meera Patturajan, Catherine E. Burgess, Corine A.M. Vernet, Li Li, Linda Gorman, Uriel M. Malyankar, Ferenc L. Boldog, Xiaojia (Sasha) Guo, Suresh G. Shenoy, Muralidhara Padigaru, Raymond J. Taupier, Charles E. Miller, Stacie J. Casman, Carol E. A. Pena, Esha A. Gangolli, Vladimir Y. Gusev, Glennda Smithson, Bryan D. Zerhusen, Valerie Gerlach, Pascale F-J Pochart, Elma R. Fernandes, Richard A. Shimkets, Luca Rastelli, Steven K. Spaderna, William J. LaRochelle, Mei Zhong, Nikolai V. Khramtsov, Edward Z. Voss, John L. Herrmann
  • Novel nucleic acid sequences encoding human KIAA0768 protein-like and human protein PRO228-like polypeptides
    Publication number: 20040002134
    Abstract: This application is drawn to novel nucleic acid sequences encoding mammalian polypeptides that have sequence similarity to human KIAA0768 protein and human protein PRO228. The nucleic acid sequence is 2862 nucleotides long and contains an open reading frame from nucleotides 508-510 to 2557-9. The novel, encoded polypeptides comprise 683 amino acid residues.
    Type: Application
    Filed: October 15, 2001
    Publication date: January 1, 2004
    Applicant: CuraGen Corporation
    Inventors: Richard A. Shimkets, Elma R. Fernandes, John L. Herrman, Corine A.M. Vernet
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040002453
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 2, 2002
    Publication date: January 1, 2004
    Inventors: John P. Alsobrook, David W. Anderson, Catherine E. Burgess, Shlomit R. Edinger, Linda Gorman, Xiaojia (Sasha) Guo, Weizhen Ji, Li Li, Meera Patturajan, Carol E. A. Pena, Daniel K. Rieger, Suresh G. Shenoy, Richard A. Shimkets, Kimberly A. Spytek, Raymond J. Taupier, Mei Zhong
  • Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
    Patent number: 6670464
    Abstract: The invention provides nucleic acids containing single-nucleotide polymorphisms identified for transcribed human sequences, as well as methods of using the nucleic acids.
    Type: Grant
    Filed: November 16, 1999
    Date of Patent: December 30, 2003
    Assignee: Curagen Corporation
    Inventors: Richard A. Shimkets, Martin Leach
  • Proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030236389
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 14, 2001
    Publication date: December 25, 2003
    Inventors: Richard A. Shimkets, Steven D. Colman, Kimberly A. Spytek, Robert A. Ballinger, Xiaojia (Sasha) Guo, Velizar T. Tchernev, Suresh G. Shenoy, Li Li, Karen Ellerman, Bryan D. Zerhusen, Meera Patturajan, Stacie J. Casman, Ferenc Boldog, Vladimir Y. Gusev, Catherine E. Burgess, Shlomit R. Edinger, Esha A. Gangolli, Uriel M. Malyankar, Erik Gunther, Glennda Smithson, Isabelle Millet, Valerie Gerlach
  • Novel nucleic acids and polypeptides and methods of use thereof
    Publication number: 20030235882
    Abstract: Disclosed are novel polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: December 19, 2001
    Publication date: December 25, 2003
    Inventors: Richard A. Shimkets, Meera Patturajan, Corine A.M. Vernet, Stacie J. Casman, Uriel M. Malyankar, Suresh G. Shenoy, Kimberly A. Spytek, Esha A. Gangolli, Charles E. Miller, Ferenc L. Boldog, Li Li, Raymond J. Taupier, Ramesh Kekuda, Glennda Smithson, Bryan D. Zerhusen, Xiaohong Liu, Steven D. Colman, Velizar T. Tchernev, Jingsheng Si, Shlomit R. Edinger, David J. Stone, Paul Sciore, Isabelle Millet, Mark E. Rothenberg
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20030232347
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: August 1, 2002
    Publication date: December 18, 2003
    Inventors: David W. Anderson, John P. Alsobrook, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Shlomit R. Edinger, Esha A. Gangolli, Linda Gorman, Xiaojia Sasha Guo, Nikolai V. Khramtsov, Denise M. Lepley, John R. MacDougall, Carol E. A. Pena, John A. Peyman, Meera Patturajan, Daniel K. Rieger, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, Corine A.M. Vernet, Edward Z. Voss, Mei Zhong
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030232331
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 4, 2001
    Publication date: December 18, 2003
    Inventors: Stacie J. Casman, Muralidhara Padigaru, Catherine E. Burgess, Richard A. Shimkets, Kimberly A. Spytek, Jennifer A. Gilbert, Jane E. Mayotte, Jason C. Baumgartner, Vishnu Mishra, Corine A.M. Vernet, Kevin S. Dickinson, Robert A. Ballinger, Adam R. Wolenc, Shlomit R. Edinger, John R. MacDougall, Glennda Smithson, Karen Ellerman, David J. Stone, Erik Gunther, Valerie Gerlach
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030228301
    Abstract: Disclosed are novel polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: October 24, 2001
    Publication date: December 11, 2003
    Inventors: Li Li, Katarzyna Furtak, Amanda Perna, Meera Patturajan, Richard A. Shimkets, Xiaojia Sasha Guo, Stacie J. Casman, Catherine E. Burgess, Uriel M. Malyankar, Velizar T. Tchernev, Corine A. Vernet, Kimberly A. Spytek, Michele Agee, Luca Rastelli, Suresh G. Shenoy, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Valerie Gerlach, Schlomit R. Edinger, John R. MacDougall, John A. Peyman, Erik Gunther, David J. Stone, Karen Ellerman, Esha A. Gangolli
  • Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
    Publication number: 20030224413
    Abstract: The invention provides nucleic acids containing single-nucleotide polymorphisms identified for transcribed human sequences, as well as methods of using the nucleic acids.
    Type: Application
    Filed: March 20, 2003
    Publication date: December 4, 2003
    Inventors: Richard A. Shimkets, Martin Leach