Patents by Inventor Richard A. Stone

Richard A. Stone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5637604
    Abstract: A composition for the inhibition of the abnormal postnatal axial growth of the eye of a maturing animal which comprises a pharmaceutically effective amount of a muscarinic pharmacological antagonist relatively selective for blocking the cholinergic receptors in cells of the brain, neural tissue and/or neural ganglia but less selective for blocking the cholinergic receptors of the cells of smooth muscles at the front of the eye, said antagonist present in a carrier or diluent suitable for ocular administration. A suitable antagonist is pirenzepine. Other suitable antagonists are telenzepine and o-methoxy-sila-hexocyclium.
    Type: Grant
    Filed: June 29, 1994
    Date of Patent: June 10, 1997
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Alan M. Laties, Richard A. Stone
  • Patent number: 5571823
    Abstract: A method of controlling the abnormal postnatal growth of the eye of a maturing animal which comprises the ocular administration of therapeutically effective amounts of a dopamine antagonist.
    Type: Grant
    Filed: June 22, 1993
    Date of Patent: November 5, 1996
    Assignees: The Trustees of the University of Pennsylvania, Emory University
    Inventors: Richard A. Stone, Alan M. Laties, Paul M. Iuvone
  • Patent number: 5567731
    Abstract: A composition for the inhibition of the abnormal postnatal axial growth of the eye of a maturing animal which comprises a pharmaceutically effective amount of a gamma aminobutyric acid antagonist relatively selective for GABA.sub.B receptors in the cells of the eye, said antagonist present in a carrier or diluent suitable for ocular administration. A suitable antagonist is 2-OH saclofen.
    Type: Grant
    Filed: September 27, 1994
    Date of Patent: October 22, 1996
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Alan M. Laties, Richard A. Stone
  • Patent number: 5461052
    Abstract: A composition for the inhibition of the abnormal postnatal axial growth of the eye of a maturing animal which comprises a pharmaceutically effective amount of a tricyclic compound, said tricyclic compound present in a carrier or diluent suitable for ocular administration. Suitable tricyclics are tertiary amines, secondary amines, and other active metabolites of tricyclic compounds.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: October 24, 1995
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Richard A. Stone, Alan M. Laties
  • Patent number: 5385939
    Abstract: A composition for the inhibition of the abnormal postnatal axial growth of the eye of a maturing animal which comprises a pharmaceutically effective amount of a gamma aminobutyric acid antagonist relatively selective for GABA.sub.B receptors in the cells of the eye, said antagonist present in a carrier or diluent suitable for ocular administration. A suitable antagonist is 2-OH saclofen.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: January 31, 1995
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Alan M. Laties, Richard A. Stone
  • Patent number: 5360801
    Abstract: A method of inducing axial elongation of an eye of an animal comprising contacting a first open animal eye with a cholinergic agonist, detecting the change in axial growth of the first eye, applying a known control agent in a second open animal eye, observing the results of the control agent on the second eye, and comparing the change in axial growth of the first eye with the change in axial growth of the second eye.
    Type: Grant
    Filed: January 14, 1993
    Date of Patent: November 1, 1994
    Assignee: The Trustees of The University of Pennsylvania
    Inventors: Alan M. Laties, Richard A. Stone
  • Patent number: 5356892
    Abstract: A composition for the inhibition of the abnormal postnatal axial growth of the eye of a maturing animal which comprises a pharmaceutically effective amount of a muscarinic pharmacological antagonist relatively selective for blocking the cholinergic receptors in cells of the brain, neural tissue and/or neural ganglia but less selective for blocking the cholinergic receptors of the cells of smooth muscles at the front of the eye, said antagonist present in a carrier or diluent suitable for ocular administration. A suitable antagonist is pirenzepine. Other suitable antagonists are telenzepine and o-methoxy-sila-hexocyclium.
    Type: Grant
    Filed: March 24, 1992
    Date of Patent: October 18, 1994
    Assignee: The Trustees of The University of Pennsylvania
    Inventors: Alan M. Laties, Richard A. Stone
  • Patent number: 5331683
    Abstract: A protective body armor garment shell is disclosed which has a front panel and a back panel made of a lightweight material and having features simulating a uniform shirt such that the garment shell can be worn over or in place of a standard uniform shirt and maintain a professional appearance while concealing the fact that body armor is being worn. The back panel is attached to the body utilizing a belt which firmly retains the garment to the body even when the front panel is loosely draped across the chest. The drapable feature allows a person wearing the garment to loosen the front panel to provide ventilation while maintaining the garment on the body, to maximize comfort.
    Type: Grant
    Filed: November 13, 1991
    Date of Patent: July 26, 1994
    Assignee: Point Blank Body Armor, Inc.
    Inventors: Richard Stone, David R. Hand
  • Patent number: 5284843
    Abstract: A method of inhibiting the abnormal postnatal axial growth of the eye of a maturing animal during conditions ordinarily leading to said abnormal growth, which comprises (1) determining the neurochemical present in the retina of said eye, eg., dopamine, the concentrations of which is reduced during said conditions, and (2) administering to said eye during post natal maturation effective amounts of said neurochemical, its agonist or its antagonist.
    Type: Grant
    Filed: April 10, 1991
    Date of Patent: February 8, 1994
    Assignees: Trustees of the University of Penna., Emory University
    Inventors: Richard A. Stone, Alan M. Laties, Paul M. Iuvone
  • Patent number: 5143598
    Abstract: Methods for the recovery of bitumen from tar sands comprising the steps of mixing tar sand, solvent and a displacing amount of aqueous medium to form a mixture, followed by separating a bitumen-rich solvent phase from the mixture and recovering bitumen from the bitumen-rich solvent phase are disclosed.
    Type: Grant
    Filed: January 14, 1988
    Date of Patent: September 1, 1992
    Assignee: Amoco Corporation
    Inventors: Robert J. Graham, John J. Helstrom, Lawrence B. Peck, Richard A. Stone, Edward J. Bernier, Jr.
  • Patent number: 5122522
    Abstract: A composition for the inhibition of the abnormal postnatal axial growth of the eye of a maturing animal which comprises a pharmaceutically effective amount of a muscarinic pharmacological antagonist relatively selective for blocking the cholinergic receptors in cells of the brain, neural tissue and/or neural ganglia but less selective for blocking the cholinergic receptors of the cells of smooth muscles at the front of the eye, said antagonist present in a carrier or diluent suitable for ocular administration. A suitable antagonist is pirenzepine. Other suitable antagonists are telenzepine and o-methoxy-sila-hexocyclium.
    Type: Grant
    Filed: May 11, 1990
    Date of Patent: June 16, 1992
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Alan M. Laties, Richard A. Stone
  • Patent number: 5073985
    Abstract: A protective body armor garment shell is disclosed which has a front panel and a back panel made of a lightweight material and having features simulating a uniform shirt such that the garment shell can be worn over or in place of a standard uniform shirt and maintain a professional appearance while concealing the fact that body armor is being worn. The back panel is attached to the body utilizing a belt which firmly retains the garment to the body even when the front panel is loosely draped across the chest. The drapable feature allows a person wearing the garment to loosen the front panel to provide ventilation while maintaining the garment on the body, to maximize comfort.
    Type: Grant
    Filed: October 22, 1990
    Date of Patent: December 24, 1991
    Assignee: Point Blank Body Armor, Inc.
    Inventors: Richard Stone, David R. Hand
  • Patent number: 5055302
    Abstract: A method and composition for inhibition of abnormal postnatal ocular growth are disclosed. The composition comprises vasoactive intestinal peptide (VIP), PHI or a analogue of these peptides. The method for inhibition of abnormal postnatal ocular growth comprises administering to the eye of an animal effective amount of VIP, PHI or analogue of these peptides.
    Type: Grant
    Filed: February 22, 1990
    Date of Patent: October 8, 1991
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Alan M. Laties, Richard A. Stone
  • Patent number: 4906355
    Abstract: A process for removing fines from a tar sands extract is provided. The tar sands extract is contacted with a specific solvent to form agglomerates and a substantial portion of the agglomerates are separated from the balance of the extract prior to any substantial attrition of the agglomerates.
    Type: Grant
    Filed: March 16, 1989
    Date of Patent: March 6, 1990
    Assignee: Amoco Corporation
    Inventors: William J. Lechnick, Richard A. Stone
  • Patent number: 4853375
    Abstract: A method of lowering intraocular pressure in the eye of a human or an animal, the method involving administering to the eye, an agent comprising an amount of tetracycline or a tetracycline related compound, such as demeclocycline, sufficient to achieve a significant lowering of intraocular pressure.
    Type: Grant
    Filed: September 16, 1987
    Date of Patent: August 1, 1989
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Theodore Krupin, Richard A. Stone
  • Patent number: 4722782
    Abstract: A method for the recovery of bitumen from tar sand comprises slurrying tar sand with about 0.5 to about 4.0 pound of a organic solvent per pound of tar sand, then adding greater than about 0.50 pound water per pound of tar sand, and separating a bitumen rich solvent phase. The method has the advantage of permitting separation of sand from the bitumen rich solvent extract without formation of a stable emulsion.
    Type: Grant
    Filed: October 31, 1983
    Date of Patent: February 2, 1988
    Assignee: Standard Oil Company
    Inventors: Robert J. Graham, John J. Helstrom, Lawrence B. Peck, Richard A. Stone
  • Patent number: 4539097
    Abstract: A method for filtering spent tar sands from a bitumen and organic solvent solution comprises separating the solution into two streams wherein the bulk of the coarser spent tar sand is in a first stream and has an average particle size of about 10 to about 100 mesh and the bulk of the finer spent tar sand is in a second stream; producing a filter cake by filtering the coarser spent tar sand from the first stream; and filtering the finer spent tar sand from the second stream with the filter cake. The method is particularly useful for filtering solutions of bitumen extracted from bitumen containing diatomite, spent diatomite and organic solvent.
    Type: Grant
    Filed: February 29, 1984
    Date of Patent: September 3, 1985
    Assignee: Standard Oil Company (Indiana)
    Inventors: Jeffrey C. Kelterborn, Richard A. Stone
  • Patent number: 4350676
    Abstract: A method of using carboxyfluorescein in ophthalmic studies comprising applying of the eye an effective amount of at least one active isomer of carboxyfluorescein.
    Type: Grant
    Filed: May 21, 1981
    Date of Patent: September 21, 1982
    Inventors: Alan M. Laties, Richard A. Stone
  • Patent number: 4208814
    Abstract: An extension device for an excavating bucket for increasing the cutting width and capacity of the bucket includes a container of generally the same cross-sectional configuration as the bucket and having attachment means for removably attaching the device on the side of the bucket and cutting edges and tines for cutting and tearing through the soil.
    Type: Grant
    Filed: August 11, 1978
    Date of Patent: June 24, 1980
    Inventor: Richard Stone
  • Patent number: 3982413
    Abstract: This is a lock which can be quickly and easily attached to the locking groove of the king pin of a trailer to block entrance of the king pin into the attaching slot of the "fifth wheel" of a tractor, the lock having a pair of pivotally connected pin-surrounding locking segments with a snap-in lock element to hold the segments in closed position and also incorporating a safety warning sign to indicate the presence of the lock on the king pin and prevent inadvertent damage to the lock or the tractor unit.
    Type: Grant
    Filed: March 17, 1975
    Date of Patent: September 28, 1976
    Inventors: Richard A. Stone, Mathias H. Riesgraf