Abstract: A stent comprises a framework that includes a sequence of cells that each occupy a discrete segment of the stent length, and each of the cells includes a plurality of struts with ends connected at respective vertices. In some forms the framework includes T-bars that connect adjacent cells, where the T-bars have a column that has a minimum width perpendicular to the long axis that is wider than a maximum width of each of the struts, and the column defines at least one slot. In other forms, the framework exhibits geometries that facilitate a high packing density for the framework when the stent is in a compressed tube or loading configuration.

Abstract: A stent comprises a framework that includes a sequence of cells that each occupy a discrete segment of the stent length, and each of the cells includes a plurality of struts with ends connected at respective vertices. An adjacent pair of the cells are attached to one another by a plurality of T-bars that each include a column defining a long axis that extends parallel to the stent axis, and a top bar attached to one end of the column. An opposite end of the column is attached to a first cell, and the top bar is attached at opposite ends to a second cell of the adjacent pair of cells. The column has a minimum width perpendicular to the long axis that is wider than a maximum width of each of the struts, and the column defines at least one slot. The top bar includes a curved edge on an opposite side from the column, and the curved edge straddles the long axis.

Abstract: A stent comprises a framework that includes a sequence of cells that each occupy a discrete segment of the stent length, and each of the cells includes a plurality of struts with ends connected at respective vertices. An adjacent pair of the cells are attached to one another by a plurality of T-bars that each include a column defining a long axis that extends parallel to the stent axis, and a top bar attached to one end of the column. An opposite end of the column is attached to a first cell, and the top bar is attached at opposite ends to a second cell of the adjacent pair of cells. The column has a minimum width perpendicular to the long axis that is wider than a maximum width of each of the struts, and the column defines at least one slot. The top bar includes a curved edge on an opposite side from the column, and the curved edge straddles the long axis.

Abstract: A stent comprises a framework that includes a sequence of cells that each occupy a discrete segment of the stent length, and each of the cells includes a plurality of struts with ends connected at respective vertices. In some forms the hollow cylindrical shape of the framework is moveable among a loading diameter that is smaller than a tube diameter, which is smaller than an expanded diameter, and every strut of the framework is oriented parallel to the stent axis when the hollow cylindrical shape is at the tube diameter. In other forms the framework includes T-bars that connect adjacent cells, where the T-bars have a column that has a minimum width perpendicular to the long axis that is wider than a maximum width of each of the struts, and the column defines at least one slot. In still other forms, the framework exhibits geometries that facilitate a high packing density for the framework when the stent is in a compressed tube or loading configuration.

Abstract: A stent comprises a framework that includes a sequence of cells that each occupy a discrete segment of the stent length, and each of the cells includes a plurality of struts with ends connected at respective vertices. An adjacent pair of the cells are attached to one another by a plurality of T-bars that each include a column defining a long axis that extends parallel to the stent axis, and a top bar attached to one end of the column. An opposite end of the column is attached to a first cell, and the top bar is attached at opposite ends to a second cell of the adjacent pair of cells. The column has a minimum width perpendicular to the long axis that is wider than a maximum width of each of the struts, and the column defines at least one slot. The top bar includes a curved edge on an opposite side from the column, and the curved edge straddles the long axis.

Abstract: The present disclosure describes intraluminal support devices having high radial stiffness regions with smaller diameter and low radial stiffness regions with larger diameter. When deployed to the vasculature of a patient in need of treatment, the high radial stiffness region is sized such that it has approximately the diameter of the vessel in need of treatment, so that it produces substantially zero chronic radial force when the vessel is not being subjected to external compression. The low radial stiffness regions anchor the device to the vessel wall and provide a less-abrupt transition from the high radial stiffness structure. Methods of making and using such devices are also described.

Abstract: Examples of a stent are provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.

Abstract: A prosthesis is disclosed including an expandable frame having a first region and a second region coupled to one another. The first region includes a transition segment and a flex segment. The stent members of the transition segment have proximal and distal apices arranged in a peak-to-peak relationship with one another. At least a portion of proximal and distal apices of the transition segment remains uncoupled to one another. The flex segment includes a stent member having proximal and distal apices arranged in a peak-to-valley relationship with the transition segment. Longitudinal tie bars are intermittently coupled between apices the flex segment and the transition segment at coupling joints. The coupling joint is located where the proximal and distal apices of the stent members of the transition segment remain uncoupled to one another. The transition and flex segments may form an alternating pattern. A flareable proximal portion may be included.

Abstract: Disclosed herein is an intraluminal support device including a closed cell design on at least one end of the device. In such a device, the closed cell structure is formed by connecting all peaks of an ultimate ring to all peaks of a penultimate ring, and all valleys of the ultimate ring to all valleys of the ultimate ring. The support device expands evenly due to this structure.

Abstract: The present disclosure describes intraluminal support devices having high radial stiffness regions with smaller diameter and low radial stiffness regions with larger diameter. When deployed to the vasculature of a patient in need of treatment, the high radial stiffness region is sized such that it has approximately the diameter of the vessel in need of treatment, so that it produces substantially zero chronic radial force when the vessel is not being subjected to external compression. The low radial stiffness regions anchor the device to the vessel wall and provide a less-abrupt transition from the high radial stiffness structure. Methods of making and using such devices are also described.

Abstract: The present disclosure describes intraluminal support devices having high radial stiffness regions with smaller diameter and low radial stiffness regions with larger diameter. When deployed to the vasculature of a patient in need of treatment, the high radial stiffness region is sized such that it has approximately the diameter of the vessel in need of treatment, so that it produces substantially zero chronic radial force when the vessel is not being subjected to external compression. The low radial stiffness regions anchor the device to the vessel wall and provide a less-abrupt transition from the high radial stiffness structure. Methods of making and using such devices are also described.

Abstract: A perfusion device and a delivery system for repair of a damaged portion of a body vessel. Perfusion device can include a tubular body that is self-expandable, having a proximal portion, a distal portion, and an intermediate portion. One or more series of barbs can be disposed circumferentially along the intermediate portion. Barbs are capable of penetrating into the tunica intima and tunica media of said vessel wall upon insertion of said device into said body vessel, and not into said tunica adventitia. A graft can be associated with the tubular body. Graft has a proximal end and a distal end, and preferably extends entirely along a luminal wall of the tubular body. Graft may also extend along an exterior surface of the tubular body at the proximal and distal portions. Delivery devices for the perfusion implant and methods of delivering the perfusion implant are also provided.

Abstract: Examples of a stent is provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain circumferential and axial engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. The length of mating elements may be sized as large as the strut width. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.

Abstract: Examples of a stent are provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.

Abstract: Disclosed herein is a delivery system and method for delivering a plurality of separate intraluminal support devices with predictable spacing. The intraluminal support devices may be self-expanding devices mounted over an inflatable balloon of a balloon catheter and adhered thereto by an adhesive. The intraluminal support devices may optionally have a flattened tip region.

Abstract: Disclosed herein is an intraluminal support device including a closed cell design on at least one end of the device. In such a device, the closed cell structure is formed by connecting all peaks of an ultimate ring to all peaks of a penultimate ring, and all valleys of the ultimate ring to all valleys of the ultimate ring. The support device expands evenly due to this structure.

Abstract: A prosthesis is disclosed including an expandable frame having a first region and a second region coupled to one another. The first region includes a transition segment and a flex segment. The stent members of the transition segment have proximal and distal apices arranged in a peak-to-peak relationship with one another. At least a portion of proximal and distal apices of the transition segment remains uncoupled to one another. The flex segment includes a stent member having proximal and distal apices arranged in a peak-to-valley relationship with the transition segment. Longitudinal tie bars are intermittently coupled between apices the flex segment and the transition segment at coupling joints. The coupling joint is located where the proximal and distal apices of the stent members of the transition segment remain uncoupled to one another. The transition and flex segments may form an alternating pattern. A flareable proximal portion may be included.

Abstract: Examples of a stent is provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain circumferential and axial engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. The length of mating elements may be sized as large as the strut width. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.

Abstract: Medical devices and methods are provided. In some aspects, devices useful for applying therapy locally within a body vessel are disclosed, the devices having a stent graft with flared end regions with a catheter providing fluid communication to the outer side of the narrower, intermediate region of the stent graft. Kits and systems including the same devices and methods are also disclosed.

Abstract: A stent graft (40) for treating Type-A dissections in the ascending aorta (22) is provided with a plurality of diameter-reducing suture loops (56-60) operable to constrain the stent graft during deployment thereof in a patient's aorta. The diameter-reducing loops (56-60) allow the stent graft (40) to be partially deployed, in such a manner that its location can be precisely adjusted in the patient's lumen. In this manner, the stent graft can be placed just by the coronary arteries (26, 28) with confidence that these will not be blocked. The stent graft (40) is also provided with proximal and distal bare stents (44,52) for anchoring purposes.