Patents by Inventor Richard A. Uhlig

Richard A. Uhlig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959140
    Abstract: A method for evaluating or monitoring metabolic effects of exercise or injury by detecting and/or quantifying microR-NAs in saliva. Compositions and methods of treatment based on detection of microRNAs.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: April 16, 2024
    Assignees: QUADRANT BIOSCIENCES INC., PENN STATE RESEARCH FOUNDATION, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Richard Uhlig, Steven D. Hicks, Frank A. Middleton
  • Patent number: 11914902
    Abstract: Shared memory access in a distributed system, including: receiving a memory access request associated with a time value; determining, based on the time value, an entry in a translation lookaside buffer (TLB); and determining, based on the entry, whether to allow the memory access request.
    Type: Grant
    Filed: February 28, 2023
    Date of Patent: February 27, 2024
    Assignee: GHOST AUTONOMY INC.
    Inventors: John Hayes, Volkmar Uhlig, Richard A. Swetz, Daniel P. Potts, Aaron Carroll
  • Patent number: 11829789
    Abstract: In the present disclosure, functions associated with the central office of an evolved packet core network are co-located onto a computer platform or sub-components through virtualized function instances. This reduces and/or eliminates the physical interfaces between equipment and permits functional operation of the evolved packet core to occur at a network edge.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: November 28, 2023
    Assignee: Intel Corporation
    Inventors: Ashok Sunder Rajan, Richard A. Uhlig, Rajendra S. Yavatkar, Tsung-Yuan C. Tai, Christian Maciocco, Jeffrey R. Jackson, Daniel J. Dahle
  • Patent number: 11453914
    Abstract: Provided are methods for detecting or diagnosing a traumatic brain injury or TBI by detecting concentration levels miRNAs associated with TBI in saliva. Methods for controlled and normalized comparisons of salivary miRNA concentration levels are further provided. Assay kits comprising salivary miRNAs, probes and/or primers for detecting salivary miRNAs are also provided.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: September 27, 2022
    Assignees: QUADRANT BIOSCIENCES INC., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, PENN STATE RESEARCH FOUNDATION
    Inventors: Steven D. Hicks, Frank A. Middleton, Richard Uhlig
  • Publication number: 20220171643
    Abstract: In the present disclosure, functions associated with the central office of an evolved packet core network are co-located onto a computer platform or sub-components through virtualized function instances. This reduces and/or eliminates the physical interfaces between equipment and permits functional operation of the evolved packet core to occur at a network edge.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 2, 2022
    Applicant: Intel Corporation
    Inventors: Ashok Sunder Rajan, Richard A. Uhlig, Rajendra S. Yavatkar, Tsung-Yuan C. Tai, Christian Maciocco, Jeffrey R. Jackson, Daniel J. Dahle
  • Patent number: 11301275
    Abstract: In the present disclosure, functions associated with the central office of an evolved packet core network are co-located onto a computer platform or sub-components through virtualized function instances. This reduces and/or eliminates the physical interfaces between equipment and permits functional operation of the evolved packet core to occur at a network edge.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: April 12, 2022
    Assignee: Intel Corporation
    Inventors: Ashok Sunder Rajan, Richard A. Uhlig, Rajendra S. Yavatkar, Tsung-Yuan C. Tai, Christian Maciocco, Jeffrey R. Jackson, Daniel J. Dahle
  • Publication number: 20220042099
    Abstract: A method and composition for detecting, diagnosing, prognosing or monitoring a subject suspected of having or having Parkinson's disease by detecting miRNAs and microbial RNAs in saliva.
    Type: Application
    Filed: October 18, 2019
    Publication date: February 10, 2022
    Applicants: QUADRANT BIOSCIENCES INC., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Frank A. MIDDLETON, Richard UHLIG
  • Patent number: 11242563
    Abstract: This application provides methods to differentiate between subjects with autism spectrum disorder (ASD) and typically developing (TD) or developmentally delayed (DD) subjects using miRNA and/or microbiome levels detected in saliva samples and patient information. The method can be used to monitor the progress of ASD and guide its treatment. RNA-seq, qPCR, or other methods determine counts and abundance of miRNA or microbiomes. MicroRNA and/or microbiome sequencing data are refined by normalization to expression levels or abundance of time-invariant miRNAs and/or microbial RN As to control for time of sample collection or to compensate for circadian fluctuations in these levels. Multivariate logistic regression and nonlinear classification techniques are further used to select a panel of miRNAs and microbiomes that accurately differentiate between subjects with ASD, DD, and TD in subjects with an unknown ASD status. These panels of miRNAs and microbiomes may be developed into a RNA assay kit.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: February 8, 2022
    Assignees: QUADRANT BIOSCIENCES INC., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, PENN STATE RESEARCH FOUNDATION
    Inventors: Steven D. Hicks, Frank A. Middleton, Richard Uhlig, Alexander Rajan
  • Patent number: 11048588
    Abstract: Embodiments of an invention for monitoring the operation of a processor are disclosed. In one embodiment, a system includes a processor and a hardware agent external to the processor. The processor includes virtualization logic to provide for the processor to operate in a root mode and in a non-root mode. The hardware agent is to verify operation of the processor in the non-root mode based on tracing information to be collected by a software agent to be executed by the processor in the root mode.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: June 29, 2021
    Assignee: Intel Corporation
    Inventors: Gilbert Neiger, Andrew V. Anderson, Richard A. Uhlig, David M. Durham, Ronak Singhal, Xiangbin Wu, Sailesh Kottapalli
  • Publication number: 20210130897
    Abstract: A method for detecting a risk of, diagnosing, prognosing, or monitoring anorexia nervosa or another eating disorder or for distinguishing a healthy subject from one with anorexia, an eating disorder, or an anxiety disorder comprising detecting at least one abnormal or altered pattern of miRNA and/or microbial RNA in biological sample compared to a control value from one or more normal subjects or healthy controls, and selecting a subject having at least one abnormal or altered pattern of miRNA and/or microbial RNA correlated with anorexia nervosa or another eating disorder. Probe and/or primer compositions for identifying miRNAs or microbial RNAs; compositions containing miRNAs or microbial RNAs, their mimics or agents that target miRNAs or microbial RNAs; and methods of treatment for AN and other eating disorders.
    Type: Application
    Filed: April 15, 2019
    Publication date: May 6, 2021
    Applicants: QUADRANT BIOSCIENCES INC., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, PENN STATE RESEARCH FOUNDATION
    Inventors: Steven D. HICKS, Frank A. MIDDLETON, Richard UHLIG
  • Publication number: 20200407795
    Abstract: A method for evaluating or monitoring metabolic effects of exercise or injury by detecting and/or quantifying microR-NAs in saliva. Compositions and methods of treatment based on detection of microRNAs.
    Type: Application
    Filed: February 27, 2019
    Publication date: December 31, 2020
    Applicants: QUADRANT BIOSCIENCES INC., PENN STATE RESEARCH FOUDATION, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Richard UHLIG, Steven D. HICKS, Frank A. MIDDLETION
  • Publication number: 20200341921
    Abstract: Embodiments of processors, methods, and systems for virtualizing interrupt prioritization and delivery are disclosed. In one embodiment, a processor includes instruction hardware and execution hardware. The instruction hardware is to receive a plurality of instructions, including a first instruction to transfer the processor from a root mode to a non-root mode for executing guest software in a virtual machine, wherein the processor is to return to the root mode upon the detection of any of a plurality of virtual machine exit events. The execution hardware is to execute the first instruction, execution of the first instruction to include determining a first virtual processor-priority value and storing the first virtual processor-priority value in a virtual copy of a processor-priority field, where the virtual copy of the processor-priority field is a virtual resource corresponding to a physical resource associated with an interrupt controller.
    Type: Application
    Filed: May 14, 2020
    Publication date: October 29, 2020
    Applicant: Intel Corporation
    Inventors: Gilbert Neiger, Rajesh Sankaran, Gideon Gerzon, Richard Uhlig, Sergiu Ghetie, Michael Neve de Mevergnies, Adil Karrar
  • Publication number: 20200277676
    Abstract: Provided are methods for detecting or diagnosing a traumatic brain injury or TBI by detecting concentration levels miRNAs associated with TBI in saliva. Methods for controlled and normalized comparisons of salivary miRNA concentration levels are further provided. Assay kits comprising salivary miRNAs, probes and/or primers for detecting salivary miRNAs are also provided.
    Type: Application
    Filed: March 23, 2018
    Publication date: September 3, 2020
    Applicants: QUADRANT BIOSCIENCES INC., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, PENN STATE RESEARCH FOUNDATION
    Inventors: Steven D. HICKS, Frank A. MIDDLETON, Richard UHLIG
  • Patent number: 10747682
    Abstract: A processor including logic to execute an instruction to synchronize a mapping from a physical address of a guest of a virtualization based system (guest physical address) to a physical address of the host of the virtualization based system (host physical address), and stored in a translation lookaside buffer (TLB), with a corresponding mapping stored in an extended paging table (EPT) of the virtualization based system.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: August 18, 2020
    Assignee: Intel Corporation
    Inventors: Steven M. Bennett, Andrew V. Anderson, Gilbert Neiger, Richard Uhlig, Scott Dion Rodgers, Rajesh M. Sankaran, Camron Rust, Sebastian Schoenberg
  • Publication number: 20200257609
    Abstract: Embodiments of an invention for monitoring the operation of a processor are disclosed. In one embodiment, a system includes a processor and a hardware agent external to the processor. The processor includes virtualization logic to provide for the processor to operate in a root mode and in a non-root mode. The hardware agent is to verify operation of the processor in the non-root mode based on tracing information to be collected by a software agent to be executed by the processor in the root mode.
    Type: Application
    Filed: February 11, 2020
    Publication date: August 13, 2020
    Applicant: Intel Corporation
    Inventors: Gilbert Neiger, Andrew V. Anderson, Richard A. Uhlig, David M. Durham, Ronak Singhal, Xiangbin Wu, Sailesh Kottapalli
  • Patent number: 10740249
    Abstract: In one embodiment of the present invention, a method includes switching between a first address space and a second address space, determining if the second address space exists in a list of address spaces; and maintaining entries of the first address space in a translation buffer after the switching. In such manner, overhead associated with such a context switch may be reduced.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: August 11, 2020
    Assignee: Intel Corporation
    Inventors: Jason W. Brandt, Sanjoy K. Mondal, Richard A. Uhlig, Gilbert Neiger, Robert T. George
  • Publication number: 20200174811
    Abstract: In the present disclosure, functions associated with the central office of an evolved packet core network are co-located onto a computer platform or sub-components through virtualized function instances. This reduces and/or eliminates the physical interfaces between equipment and permits functional operation of the evolved packet core to occur at a network edge.
    Type: Application
    Filed: February 10, 2020
    Publication date: June 4, 2020
    Applicant: Intel Corporation
    Inventors: Ashok Sunder Rajan, Richard A. Uhlig, Rajendra S. Yavatkar, Tsung-Yuan C. Tai, Christian Maciocco, Jeffrey R. Jackson, Daniel J. Dahle
  • Publication number: 20200157625
    Abstract: This application provides methods to differentiate between subjects with autism spectrum disorder (ASD) and typically developing (TD) or developmentally delayed (DD) subjects using miRNA and/or microbiome levels detected in saliva samples and patient information. The method can be used to monitor the progress of ASD and guide its treatment. RNA-seq, qPCR, or other methods determine counts and abundance of miRNA or microbiomes. MicroRNA and/or microbiome sequencing data are refined by normalization to expression levels or abundance of time-invariant miRNAs and/or microbial RN As to control for time of sample collection or to compensate for circadian fluctuations in these levels. Multivariate logistic regression and nonlinear classification techniques are further used to select a panel of miRNAs and microbiomes that accurately differentiate between subjects with ASD, DD, and TD in subjects with an unknown ASD status. These panels of miRNAs and microbiomes may be developed into a RNA assay kit.
    Type: Application
    Filed: March 22, 2018
    Publication date: May 21, 2020
    Applicants: Quadrant Biosciences Inc., The Research Foundation for the State University of New York, Penn State Research Foundation
    Inventors: Steven D. HICKS, Frank A. MIDDLETON, Richard UHLIG, Alexander RAJAN
  • Publication number: 20200157626
    Abstract: Methods for diagnosing or monitoring a condition, disorder or disease associated with circadian, diurnal or other temporal rhythms by detecting circa-miRNAs and circa-microbiomes associated with said condition, disorder or disease. Methods for correcting or normalizing sequence data to correct for diurnal or circadian fluctuations in quantities of circa-miRNAs and/or circa-microbiomes by adjusting or normalizing values based on the time of day when a saliva sample containing these RNAs was collected.
    Type: Application
    Filed: March 20, 2018
    Publication date: May 21, 2020
    Applicants: Quadrant Biosciences Inc., The Research Foundation for the State University of New York, Penn State Research Foundation
    Inventors: Steven D. HICKS, Frank A. MIDDLETON, Richard UHLIG
  • Patent number: 10599455
    Abstract: Embodiments of apparatuses and methods for processing virtualization events in a layered virtualization architecture are disclosed. In one embodiment, an apparatus includes a hardware processor including event circuit to recognize a virtualization event, and evaluation circuit to determine whether to transfer control of the apparatus from a child guest to a parent guest in response to the virtualization event, wherein the child guest and the parent guest each include a bit per virtualization event to indicate whether the parent guest is to gain control when the virtualization event occurs.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: March 24, 2020
    Assignee: Intel Corporation
    Inventors: Steven M. Bennett, Andrew V. Anderson, Gilbert Neiger, Dion Rodgers, Richard A. Uhlig, Lawrence O. Smith, Barry E. Huntley