Patents by Inventor Richard Allen HOUGHTEN

Richard Allen HOUGHTEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein acyl transferase inhibitors and methods of treatment
    Patent number: 10085981
    Abstract: Embodiments of the present disclosure include compositions and pharmaceutical compositions that include protein acyl transferases (PAT) inhibitors, methods of treating a condition or disease, methods of treating autopalmitoylation activity, and the like.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: October 2, 2018
    Assignees: University of South Florida, Torrey Pines Institute for Molecular Studies
    Inventors: Robert Joseph Deschenes, Marcello Angelo Giulianotti, Richard Allen Houghten, David Allen Mitchell, Laura Dawn Hamel
  • Bis-cyclic guanidine compound compositions, methods of use and treatment thereof
    Patent number: 10052309
    Abstract: The present disclosure provides compositions including a bis-cyclic guanidine compound, pharmaceutical compositions including a bis-cyclic guanidine compound, methods of treatment of a condition (e.g., bacterial infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: August 21, 2018
    Assignees: University of South Florida, Torrey Pines Institute for Molecular Studies
    Inventors: Lindsey Neil Shaw, Renee Marie Fleeman, Richard Allen Houghten, Marcello Angelo Giulianotti, Radleigh G. Santos, Adel Nefzi
  • PROTEIN ACYL TRANSFERASE INHIBITORS AND METHODS OF TREATMENT
    Publication number: 20180200250
    Abstract: Embodiments of the present disclosure include compositions and pharmaceutical compositions that include protein acyl transferases (PAT) inhibitors, methods of treating a condition or disease, methods of treating autopalmitoylation activity, and the like.
    Type: Application
    Filed: July 13, 2016
    Publication date: July 19, 2018
    Applicants: University of South Florida, TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
    Inventors: ROBERT JOSEPH DESCHENES, MARCELLO ANGELO GIULIANOTTI, RICHARD ALLEN HOUGHTEN, DAVID ALLEN MITCHELL, LAURA DAWN HAMEL
  • Bacterial topoisomerase inhibitors and use thereof
    Patent number: 9988341
    Abstract: The present invention provides novel compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: June 5, 2018
    Assignees: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES, TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
    Inventors: Yuk-Ching Tse-Dinh, Marcello Angelo Giulianotti, Richard Allen Houghten
  • BIS-CYCLIC GUANIDINE COMPOUND COMPOSITIONS, METHODS OF USE AND TREATMENT THEREOF
    Publication number: 20180036286
    Abstract: The present disclosure provides compositions including a bis-cyclic guanidine compound, pharmaceutical compositions including a bis-cyclic guanidine compound, methods of treatment of a condition (e.g., bacterial infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: August 31, 2017
    Publication date: February 8, 2018
    Inventors: Lindsey Neil Shaw, Renee Marie Fleeman, Richard Allen Houghten, Marcello Angelo Giulianotti, Radleigh G. Santos, Adel Nefzi
  • BACTERIAL TOPOISOMERASE INHIBITORS AND USE THEREOF
    Publication number: 20170298004
    Abstract: The present invention provides novel compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
    Type: Application
    Filed: April 19, 2017
    Publication date: October 19, 2017
    Applicant: The Florida International University Board of Trustees
    Inventors: Yuk-Ching TSE-DINH, Marcello Angelo GIULIANOTTI, Richard Allen HOUGHTEN
  • BIS-cyclic guanidine compound compositions, methods of use and treatment thereof
    Patent number: 9782388
    Abstract: The present disclosure provides compositions including a bis-cyclic guanidine compound, pharmaceutical compositions including a bis-cyclic guanidine compound, methods of treatment of a condition {e.g., bacterial infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: October 10, 2017
    Assignees: University of South Florida, Torrey Pines Institute for Molecular Studies
    Inventors: Lindsey Neil Shaw, Renee Marie Fleeman, Richard Allen Houghten, Marcello Angelo Giulianotti, Radleigh G. Santos, Adel Nefzi
  • BIS-CYCLIC GUANIDINE COMPOUND COMPOSITIONS, METHODS OF USE AND TREATMENT THEREOF
    Publication number: 20170065564
    Abstract: The present disclosure provides compositions including a bis-cyclic guanidine compound, pharmaceutical compositions including a bis-cyclic guanidine compound, methods of treatment of a condition {e.g., bacterial infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: February 19, 2015
    Publication date: March 9, 2017
    Inventors: Lindsey Neil SHAW, Renee Marie FLEEMAN, Richard Allen HOUGHTEN, Marcello Angelo GIULIANOTTI, Radleigh G. SANTOS, Adel NEFZI