Abstract: The present disclosure relates to methods and systems for assessing the risk of a human subject for developing a disease such as coronary artery disease, atrial fibrillation or Type 2 diabetes. These methods may be combined with the subjects clinical risk to improve risk analysis. Such methods may be used to assist decision making about appropriate therapeutic and monitoring regimens.

Abstract: The present disclosure relates to methods and systems for assessing the risk of a human subject developing a severe response to a Coronavirus infection, such as a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection.

Abstract: The present disclosure relates to methods and systems for assessing the risk of a human subject developing a severe response to a Coronavirus infection, such as a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection.

Abstract: The present disclosure relates to methods and systems for assessing the risk of a human female subject for developing breast cancer. In particular, the present disclosure relates to combining clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: Methods and systems for assessing the risk of a human female subject for developing breast cancer. In particular, the present disclosure relates to combining a first clinical risk assessment, a second clinical assessment based at least on breast density, and a genetic risk assessment, to obtain an improved risk analysis.

Abstract: The present disclosure relates to methods and systems for assessing the risk of a human female subject for developing breast cancer. In particular, the present disclosure relates to combining clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: The present disclosure relates to methods and systems for assessing the risk of a human female subject for developing a breast cancer. In particular, the present disclosure relates to combining simplified clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: The present disclosure relates to methods and systems for assessing the risk of a human female subject for developing breast cancer. In particular, the present disclosure relates to combining clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: The present invention relates to a method of enriching fetal nuclei from a sample. Enriched fetal nuclei can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.

Abstract: The present disclosure relates to methods and systems for assessing the risk of a human female subject for developing breast cancer. In particular, the present disclosure relates to combining clinical risk assessment and genetic risk assessment to improve risk analysis.

Abstract: An apparatus including an acoustic transducer configured to acoustically associate with at least a portion of a fluid cavity. The fluid cavity is configured as a resonator. The acoustic transducer is configured to create an acoustic wave in the at least a portion of the fluid cavity. The acoustic wave is selected to increase the concentration of at least one particulate in a location in the fluid cavity.

Abstract: A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube (4) having a first end (5) adapted for insertion through the external orifice (external os) of said patient's cervix and a second end (6) including a handle means (7) for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end (5) includes a sampling head (9, 14) adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimize the transcervical sampling site.

Abstract: A solar energy collecting panel includes a support substrate and one or more solar energy receiving surface disposed on the support substrate. The panel is mountable to extend in a mounting plane across an underlying structure. The support substrate is configured so that when the panel is mounted to the underlying structure at least a portion of the solar energy receiving surface is at an inclined angle to the mounting plane.

Abstract: A brine discharge assembly includes a discharge pipe having a body that defines an interior passage, a pipe inlet, and a pipe outlet spaced from the pipe inlet. The pipe inlet and pipe outlet are able to be in fluid communication with the interior passage, and the pipe is connectable to a source of brine and configured to convey the brine from the pipe inlet to the pipe outlet. The brine discharge assembly also includes a dilution assembly able to be connected to a source of liquid diluent. The dilution assembly includes one or more injectors and one or more ports, and is coupled to the pipe so that the one or more ports are able to be in fluid communication with the interior passage of the pipe intermediate the pipe inlet and pipe outlet. The one or more injectors are configured to inject the liquid diluent into the interior passage of the pipe through the one or more ports.

Abstract: A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube (4) having a first end (5) adapted for insertion through the external orifice (external os) of said patient's cervix and a second end (6) including a handle means (7) for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end (5) includes a sampling head (9, 14) adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimise the transcervical sampling site.

Abstract: A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube (4) having a first end (5) adapted for insertion through the external orifice (external os) of said patient's cervix and a second end (6) including a handle means (7) for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end (5) includes a sampling head (9, 14) adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimise the transcervical sampling site.

Abstract: The present invention relates to methods of enriching fetal cells from a pregnant female. The present invention relates to removing, from a sample, cells that comprise at least one MHC molecule. The present invention also relates to methods that rely on using telomerase, mRNA encoding components thereof, as well as telomere length, as markers for fetal cells. Enriched fetal cells can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.

Abstract: This application relates to methods for enriching DNA from a first cell type from a sample comprising DNA from the first cell type and DNA from a second cell type, wherein the first cell type methylates DNA to a lesser extent than the second cell type. DNA is enriched by, selecting for fragments by size after digestion of the sample with a methylation-sensitive restriction enzyme. Cell types of interest include fetal cells and cancerous cells. The enriched DNA can be used for a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.

Abstract: Solar energy collecting panels, mounting systems for solar energy collecting panels, and techniques for mounting the solar energy collecting panels are disclosed. A mounting system for solar energy collecting panels includes a base assembly having rails securable to an underlying structure. The rails include panel mountings configured to receive mounting assemblies of the panels for mounting the panels to the rails so that in use each rail has mounted to it multiple panels whilst each panel is mounted to two or more of the rails.

Abstract: The present invention relates to a method of enriching free fetal nucleic acids from a cervical sample. The enriched fetal nucleic acids can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.