Abstract: Among other things, calibration of a signal processing system is disclosed to minimize vector mismatch between signals frequency-translated from an RF signal and conveyed along a plurality of signal paths of the signal processing system. A calibration signal having a plurality of tones is coupled to the signal processing system such that it is frequency translated. The frequency-translated calibration signal is sampled along a first signal path of the signal processing system to obtain a first set of observed samples. It is also sampled along a second signal path of the system to obtain a second set of observed samples. The first set of observed samples is filtered with an adaptive filter having a set of adaptable coefficients to obtain a set of filtered samples. The coefficients are adapted to minimize undesired deviations between the set of filtered samples and the second set of observed samples.