Patents by Inventor Richard Andrew Castledine

Richard Andrew Castledine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for synthesis and purification of (2R,6R)-hydroxynorketamine
    Patent number: 11186539
    Abstract: A process for the preparation of (2R,6R)-hydroxynorketamine is provided. The process requires no chromatography purification and affords the (2R,6R)-hydroxynorketamine in eight steps with a 26% overall yield and greater than 97% purity.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: November 30, 2021
    Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Craig J. Thomas, Patrick Joseph Morris, Richard Andrew Castledine, Samuel Lawrence Bourne
  • PROCESS FOR SYNTHESIS AND PURIFICATION OF (2R,6R)-HYDROXYNORKETAMINE
    Publication number: 20210246099
    Abstract: A process for the preparation of (2R, 6R)-hydroxynorketamine is provided. The process requires no chromatography purification and affords the (2R, 6R)-hydroxynorketamine in eight steps with a 26% overall yield and greater than 97% purity.
    Type: Application
    Filed: June 4, 2020
    Publication date: August 12, 2021
    Inventors: Craig J. Thomas, Patrick Joseph Morris, Richard Andrew Castledine, Samuel Lawrence Bourne