Patents by Inventor Richard Antonius Janssen

Richard Antonius Janssen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGET SEQUENCES AND METHODS TO IDENTIFY THE SAME, USEFUL IN TREATMENT OF NEURODEGENERATIVE DISEASES
    Publication number: 20110105587
    Abstract: The present invention relates to methods and assays for identifying agents capable of inhibiting the mutant huntingtin protein, inhibiting or reducing cell death, in particular cell death associated with polyglutamine-induced protein aggregation, which inhibition is useful in the prevention, amelioration and/or treatment of neurodegenerative diseases, and Huntington's disease more generally. In particular, the present invention provides methods and assays for identifying agents for use in the prevention and/or treatment of Huntingtons disease. The invention provides polypeptide and nucleic acid TARGETs and siRNA sequences based on these TARGETS.
    Type: Application
    Filed: February 3, 2009
    Publication date: May 5, 2011
    Inventors: David Frederik Fishcher, Richard Antonius Janssen, Remko De Pril, Desiré Maria Petronella Catharina Van Steenhoven, Seung Kwak, David S. Howland, Ethan Signer