Patents by Inventor Richard B. Bankert

Richard B. Bankert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHOSPHATIDYLSERINE BINDING MOLECULES BLOCK IMMUNE SUPPRESSION OF TUMOR ASSOCIATED EXOSOMES
    Publication number: 20220305025
    Abstract: The present disclosure provides compounds that bind phosphatidylserine (PS). Also provided are compositions comprising the compounds and methods of using the compounds and/or compositions. The compounds and compositions may be used to treat an individual having or suspected of having cancer(s), infectious disease(s), chronic inflammation, and/or autoimmune condition(s).
    Type: Application
    Filed: August 17, 2020
    Publication date: September 29, 2022
    Inventors: Richard B. BANKERT, Koon Yan PAK, Brian D. GRAY, Sathy V. BALU-IYER, Raymond KELLEHER, Gautam SHENOY, Maulasri BHATTA
  • Compositions and methods of preparation of liposomal microparticulate IL-12
    Patent number: 7662405
    Abstract: This invention provides methods and compositions for localized delivery of IL-12 to a desired site. The composition comprises liposomes carrying IL-12. The liposomes comprise phosphatidyl choline, phosphatidyl glycerol and cholesterol. The size and composition of the liposomes is such that there is minimal leakage into the systemic circulation. These compositions can be used for delivery of IL-12 to selected sites such as tumors.
    Type: Grant
    Filed: August 9, 2006
    Date of Patent: February 16, 2010
    Assignee: The Research Foundation of State University of New York
    Inventors: Sathy V. Balu-Iyer, Richard B. Bankert, Vivek S. Purohit
  • Method of enhancing immunogenicity by covalent linkage of antigens to proteins on the surface of dendritic cells
    Publication number: 20030118569
    Abstract: A method is provided to increase the immunogenicity of an antigen. This method involves the covalent coupling of the antigen to proteins or glycoproteins present on the surface of dendritic cells by a mild biochemical modification which minimizes the denaturation of the antigen and preserving cell viability. Dendritic cells with covalently linked antigen on their surface can be used for generating a specific response to the antigen. The present method can be used for both therapeutic and preventive purposes.
    Type: Application
    Filed: December 18, 2002
    Publication date: June 26, 2003
    Inventors: Richard B. Bankert, Nejat Egilmez
  • Methods and products for tumor immunotherapy using cytokines
    Publication number: 20020110538
    Abstract: The invention relates to methods and products for preventing and treating tumors. In particular the invention relates to the use of slow release microparticles containing cytokines, which are directly injected into a tumor, in order to treat the tumor, e.g., cause tumor regression or to prevent tumor growth or metastasis.
    Type: Application
    Filed: December 27, 2000
    Publication date: August 15, 2002
    Applicant: Health Research, Inc.
    Inventors: Edith Mathiowitz, Yong S. Jong, Nejat K. Egilmez, Richard B. Bankert, Jules S. Jacob
  • Methods and products for tumor immunotherapy
    Publication number: 20010043914
    Abstract: The invention relates to methods and products for preventing and treating tumors. In particular the invention relates to the use of slow release microparticles containing IL-12, which are directly injected into a tumor, in order to treat the tumor or to prevent tumor growth or metastasis.
    Type: Application
    Filed: December 27, 2000
    Publication date: November 22, 2001
    Inventors: Edith Mathiowitz, Yong S. Jong, Jules S. Jacob, Nejat K. Egilmez, Richard B. Bankert
  • Microflotation devices used for immunoassays and cell/molecular fractionation
    Patent number: 5017472
    Abstract: This invention relates to a flotation immunoassay employing a novel buoyant matrix to which an antigen or antibody is coupled and which separates the bound and free products of the assay by floating to the surface of the reaction liquid. The novel flotation device which makes it possible to detect and to quantitate either antigen or antibody can also be used to fractionate cells and molecules.
    Type: Grant
    Filed: September 9, 1987
    Date of Patent: May 21, 1991
    Inventors: Richard B. Bankert, Elizabeth A. Repasky
  • Use of milk globules as carriers for drugs
    Patent number: 4994496
    Abstract: This invention relates to a carrier for the transport of drugs in a mammalian system comprising milk fat globules.
    Type: Grant
    Filed: September 9, 1987
    Date of Patent: February 19, 1991
    Inventors: Elizabeth A. Repasky, Richard B. Bankert
  • Coated cells and their use
    Patent number: 4529712
    Abstract: Heterobifunctional reagents are used to conjugate molecules or macromolecular structures (e.g., antigens or antibodies) to membranes of non-nucleated or nucleated cells, or to liposomes, these cells being useful in highly sensitive hemolytic or immunocytoadherence assays to detect picogram quantities of antibodies or antigens.
    Type: Grant
    Filed: September 18, 1981
    Date of Patent: July 16, 1985
    Assignee: Research Corporation
    Inventors: Yi-Her Jou, Richard B. Bankert