Abstract: The invention pertains to methods and devices for the long term, in vitroculture of hematopoietic progenitor cells in the absence of exogenously added hematopoietic growth factors, improved methods for the introduction of foreign genetic material into cells of hematopoietic origin, and to apparatus for performing these methods. The hematopoietic progenitor cells are cultured on a three-dimensional porous biomaterial. The three-dimensional porous biomaterial enhances hematopoietic progenitor cell survival and leads to an expansion of progenitor cell numbers and/or functionality, while maintaining progenitor cell pluripotency in the absence of exogenous growth factors. In addition, the three-dimensional porous biomaterial supports high level transduction on cells cultured upon such environment.

Abstract: An apparatus and method for performing a surgical procedure on first and second adjacent circular portions of mucosa of tubular tissue wherein a first supporting member supports the first circular portion of mucosa, a second supporting member supports the second adjacent circular portion of mucosa and with a body tubular tissue holder positioned on the first or second supporting members. The body tubular tissue holder has a plurality of holding members oriented to hold the first or second adjacent circular portions of mucosa to secure the first and second adjacent portions of mucosa to provide for attachment of the first circular portion of mucosa to the adjacent second circular portion of mucosa.

Abstract: The invention pertains to methods and devices for the long term, in vitroculture of hematopoietic progenitor cells in the absence of exogenously added hematopoietic growth factors, improved methods for the introduction of foreign genetic material into cells of hematopoietic origin, and to apparatus for performing these methods. The hematopoietic progenitor cells are cultured on a three-dimensional porous biomaterial. The three-dimensional porous biomaterial enhances hematopoietic progenitor cell survival and leads to an expansion of progenitor cell numbers and/or functionality, while maintaining progenitor cell pluripotency in the absence of exogenous growth factors. In addition, the three-dimensional porous biomaterial supports high level transduction on cells cultured upon such environment.

Abstract: The invention pertains to methods and devices for the long term, in vitroculture of hematopoietic progenitor cells in the absence of exogenously added hematopoietic growth factors, improved methods for the introduction of foreign genetic material into cells of hematopoietic origin, and to apparatus for performing these methods. The hematopoietic progenitor cells are cultured on a three-dimensional porous biomaterial. The three-dimensional porous biomaterial enhances hematopoietic progenitor cell survival and leads to an expansion of progenitor cell numbers and/or functionality, while maintaining progenitor cell pluripotency in the absence of exogenous growth factors. In addition, the three-dimensional porous biomaterial supports high level transduction on cells cultured upon such environment.

Abstract: The invention pertains to methods and devices for the long term, in vitro culture of hematopoietic progenitor cells in the absence of exogenously added hematopoietic growth factors, improved methods for the introduction of foreign genetic material into cells of hematopoietic origin, and to apparatus for performing these methods. The hematopoietic progenitor cells are cultured on a three-dimensional porous biomaterial. The three-dimensional porous biomaterial enhances hematopoietic progenitor cell survival and leads to an expansion of progenitor cell numbers and/or functionality, while maintaining progenitor cell pluripotency in the absence of exogenous growth factors. In addition, the three-dimensional porous biomaterial supports high level transduction on cells cultured upon such environment.

Abstract: A refractory composite structure is formed which comprises a ductile refractory metallic layer with a roughened surface which is tightly bonded to a refractory composite structural shell. The roughened surface is preferably dendritic in form and produced by chemical vapor deposition techniques. The refractory composite structural shell is preferably a carbon-carbon composite formed by applying a carbon filament preform to the roughened surface, infiltrating the preform with a carbon matrix precursor, and carbonizing the precursor.

Abstract: A refractory composite structure comprising a ductile refractory metallic layer with a roughened surface which is tightly bonded to a refractory composite structural shell. The roughened surface is dendritic in form and is produced by chemical vapor deposition techniques.

Abstract: An airbag assembly including an inflatable airbag, an ignitable propellant charge for generating inflating gas and a filter between the interior of the airbag and the propellant charge. The filter comprising a porous carbon foam substrate coated substantially throughout with a thermally and structurally stable material which has been formed in situ by chemical vapor deposition techniques.

Abstract: A high temperature resistant structure which is capable of withstanding temperatures well in excess of 2500 degrees Fahrenheit in oxidizing environments for periods of at least several hours. A high temperature resistant substrate such as carbon carbon composite is coated in situ with very thin alternate layers of silicon carbide and a carbide formed from hafnium or zirconium. The coating is preferably formed using chemical vapor deposition procedures.

Abstract: A tantalum open cell structure is formed by chemical vapor deposition onto a reticulated carbon foam substrate. Tantalum has a long history of use as an implant material, in both bone and soft tissue. This lightweight, strong, porous structure, mimicking the microstructure of natural cancellous bone, acts as a matrix for the incorporation of bone, providing optimal permeability and a high surface area to encourage new bone ingrowth.

Abstract: A high temperature resistant reticulated porous foam structure for use as a diesel emission particulate trap. A reticulated porous foam substrate which is capable of maintaining its structural integrity at temperatures in excess of approximately 2500, and preferably 2700, degrees Fahrenheit is coated with a formed in situ oxidation resistant coating which extends substantially throughout the interstices of the porous foam structure. The coating comprises very thin alternate layers of silicon carbide and a carbide formed from a Group IVA metal which has a melting point in excess of approximately 1850 degrees Centigrade.

Abstract: A sphere particularly suitable for ball point pens having a core capable of withstanding temperature in excess of 800.degree. C. and a chemically vapor deposited coating on the core, the combined diameter of core and coating ranging from approximately 0.5 to approximately 1 mm in diameter. For example, the core may consist of a metal such as tungsten, nickel, copper or molybdenum; or alternatively the core may consist of a ceramic such as aluminum oxide or graphite. The vapor deposited coating may consist of a metal carbide such as tungsten carbide, titanium carbide, tantalum carbide or niobium carbide. Alternatively the coating may consist of a metal boride such as titanium diboride.

Abstract: A heat radiating coating of rhenium for a refractory core which may be used for a rotating X-ray anode, power tube or the like. The coating is characterized by a multiplicity of needle-like radiation-reflecting elements disposed adjacent to each other. The needles have such steep angles that incoming radiation is substantially absorbed thereby by repeated reflection. Since the coating has a high radiation absorption coefficient it has a corresponding high emissivity on the order of 0.9 at elevated temperatures. A process is disclosed for depositing such a heat radiating coating of rhenium by chemical vapor deposition.

Abstract: A sphere particularly suitable for ball point pens having a core capable of withstanding temperature in excess of 800.degree. C. and a chemically vapor deposited coating on the core, the combined diameter of core and coating ranging from approximately 0.5 to approximately 1 mm in diameter. For example, the core may consist of a metal such as tungsten, nickel, copper or molybdenum; or alternatively the core may consist of a ceramic such as aluminum oxide or graphite. The vapor deposited coating may consist of a metal carbide such as tungsten carbide, titanium carbide, tantalum carbide or niobium carbide. Alternatively the coating may consist of a metal boride such as titanium diboride.