Patents by Inventor Richard B. Marchase

Richard B. Marchase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucose-6-phosphate uptake inhibitors and novel uses thereof
    Patent number: 5643883
    Abstract: The present invention provides a composition of matter comprising an inhibitor of glucose-6-phosphate uptake. Also provided is a method of inhibiting the import of glucose-6-phosphate into the endoplasmic reticulum of a cell, comprising the step of adminstering a pharmacologically effective dose of a glucose analogue to said cell. Further provided is a method of inhibiting intracellular endoplasmic reticular concentrations of calcium, comprising the step of administering to a cell a pharmacologically effective dose of a glucose-6-phosphate uptake inhibitor.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: July 1, 1997
    Assignee: UAB Research Foundation
    Inventors: Richard B. Marchase, Sudha Darbha