Patents by Inventor Richard B. Roth

Richard B. Roth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sample Preparation Device and Methods for Using Same
    Publication number: 20230039793
    Abstract: Aspects of the present disclosure include sample preparation cartridges including a cylindrical structure and one or more covers. The cylindrical structure further includes a top, a bottom, an annular wall, a plurality of cavities in the annular wall that form a plurality of open-sided chambers on the annular wall and one or more interconnections providing fluidic communication between the plurality of chambers. The one or more covers cover the open side of the plurality of chambers. Also provided is a cylinder housing comprising one or more magnets. The sample preparation cartridge is removably disposed into the cylinder housing or adjacent to the cylinder housing. Methods of using the sample preparation device are also provided.
    Type: Application
    Filed: December 23, 2020
    Publication date: February 9, 2023
    Inventors: Austin M. Derfus, Karthikeyan Kumaravadivelu, Neil Quitoviera, Adrian P. Crute, Timothy L. Higby, Richard B. Roth, Aric Joneja, Torsten Gliewe
  • Nicking and extension amplification reaction for the exponential amplification of nucleic acids
    Patent number: 9689031
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Grant
    Filed: July 14, 2007
    Date of Patent: June 27, 2017
    Assignee: Ionian Technologies, Inc.
    Inventors: Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod W. Provins, Richard B Roth, Jeffrey G. Mandell
  • Nicking and extension amplification reaction for the exponential amplification of nucleic acids
    Patent number: 9617586
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: April 11, 2017
    Assignee: Ionian Technologies, Inc.
    Inventors: Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod Provins, Richard B. Roth, Jeffrey Mandell
  • METHODS FOR IDENTIFYING RISK OF BREAST CANCER AND TREATMENTS THEREOF
    Publication number: 20090317816
    Abstract: Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
    Type: Application
    Filed: March 9, 2009
    Publication date: December 24, 2009
    Applicant: Sequenom, Inc.
    Inventors: Richard B. Roth, Matthew Roberts Nelson, Stefan M. Kammerer, Andreas Braun, Rikard Reneland
  • METHODS FOR IDENTIFYING RISK OF BREAST CANCER AND TREATMENTS THEREOF
    Publication number: 20090258344
    Abstract: Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
    Type: Application
    Filed: May 27, 2004
    Publication date: October 15, 2009
    Applicant: SEQUENOM, INC.
    Inventors: Richard B. Roth, Matthew Roberts Nelson, Andreas Braun, Stefan M. Kammerer, Mikhail F. Denissenko, Rikard Reneland, Caridad Rosette, Carolyn R. Hoyal-Wrightson
  • Methods for identifying risk of breast cancer and treatments thereof
    Patent number: 7510835
    Abstract: Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: March 31, 2009
    Assignee: Sequenom, Inc.
    Inventors: Richard B. Roth, Matthew Roberts Nelson, Stefan M. Kammerer, Andreas Braun, Rikard Reneland
  • NICKING AND EXTENSION AMPLIFICATION REACTION FOR THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
    Publication number: 20090081670
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Application
    Filed: July 14, 2008
    Publication date: March 26, 2009
    Applicant: Ionian Technologies, Inc.
    Inventors: Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod Provins, Richard B. Roth, Jeffrey Mandell
  • NICKING AND EXTENSION AMPLIFICATION REACTION FOR THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
    Publication number: 20090017453
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Application
    Filed: July 14, 2007
    Publication date: January 15, 2009
    Inventors: Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod W. Provins, Richard B. Roth, Jeffrey G. Mandell
  • Diagnosing predisposition to fat deposition and therapeutic methods for reducing fat deposition and treatment of associated conditions
    Publication number: 20040018533
    Abstract: Provided herein are methods for prognosing and diagnosing fat deposition and related disorders (e.g., obesity and non-insulin diabetes dependent mellitus (NIDDM)) in a subject, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for reducing fat deposition and related disorders, and therapeutic methods for reducing fat deposition or treating fat deposition related disorders in a subject. These embodiments are based in part upon an analysis of polymorphic variations of the nucleic acid set forth in SEQ ID NO:1.
    Type: Application
    Filed: June 4, 2003
    Publication date: January 29, 2004
    Inventors: Gail Isabel Reid Adam, Maria L. Langdown, Richard B. Roth, Mikhail F. Denissenko, Kevin J. Smylie