Abstract: In various embodiments method are provided for generating expression cassettes and gene therapy vectors comprising those cassettes that recapitulate the spatiotemporal pattern of expression of the endogenous gene. In certain embodiments the methods comprise (i) selecting a target gene; (ii) identifying putative regulatory elements associated with the target gene; (iii) determining if the regulatory element is a key regulatory element and (iv) providing a list of the key regulatory elements identified in step (iii).

Abstract: A GNSS control system and method are provided for guiding, navigating and controlling a motive component, such as a tractor, and a working component, such as an implement. A vector position/heading sensor is mounted on the motive component and includes multiple antennas connected to a GNSS receiver. The sensor also includes inertial sensors and a direction sensor, which are connected to a microprocessor of a steering control module (SCM). The SCM can be hot swapped among different vehicles and can interface with their respective original, onboard control systems. The implement can be provided with an optional GNSS antenna, receiver or both, and can be guided independently of the motive component. The SCM can be preprogrammed to guide the vehicle over a field in operating modes including straight line, contour, concentric circle and point+direction.

Abstract: An articulated equipment position control system and method are provided for equipment consisting of motive and working components. The components are connected by an articulated connector, such as a pivotal hitch. GPS-derived positional data is utilized for power-articulating the hitch to maintain the working component, such as an implement, on a predetermined course. Operator-inducted course deviations can thus be corrected. The working component can also be positioned to follow the course of the movive component. The system includes a microprocessor control subsystem, which interfaces with a steering guidance system.

Abstract: An articulated equipment position control system and method are provided for equipment consisting of motive and working components. The components are connected by an articulated connector, such as a pivotal hitch. GPS-derived positional data is utilized for power-articulating the hitch to maintain the working component, such as an implement, on a predetermined course. Operator-induced course deviations can thus be corrected. The working component can also be positioned to follow the course of the motive component. The system includes a microprocessor control subsystem, which interfaces with a steering guidance system.

Abstract: An articulated equipment position control system and method are provided for equipment consisting of motive and working components. The components are connected by an articulated connector, such as a pivotal hitch. GPS-derived positional data is utilized for power-articulating the hitch to maintain the working component, such as an implement, on a predetermined course. Operator-induced course deviations can thus be corrected. The working component can also be positioned to follow the course of the motive component. The system includes a microprocessor control subsystem, which interfaces with a steering guidance system.

Abstract: A method for increasing stability of a Coriolis mass flow meter by relieving residual and internal stress within the flow tube and related structures of the meter. The method including the steps of bending the flow tube in the desired form, fixing related flow tube structures onto the flow tube, clamping the flow tube so as to maintain the desired form during subsequent processes, annealing the flow tube, and cryogenically cooling the flow tube. An apparatus to be utilized along with the method of the present invention fixes the flow tube during the annealing and cryogenic cooling treatment processes to maintain the desired shape of the flow tube. The invention also contemplates the flow tube made in accordance with the method of the present invention.